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The map label for this gene is ribD* [H]

Identifier: 15888505

GI number: 15888505

Start: 1161893

End: 1163137

Strand: Direct

Name: ribD* [H]

Synonym: Atu8148

Alternate gene names: 15888505

Gene position: 1161893-1163137 (Clockwise)

Preceding gene: 15888504

Following gene: 159184646

Centisome position: 40.89

GC content: 61.69

Gene sequence:

>1245_bases
GTGACGAGCCGCGCCGATGACGAAAAATTCATGGCCCGTGCAATCGAGGTTTCGCTTCGCCACCAGGGCCAGACGCTGAC
CAATCCCTCGGTTGGCTGTGTTCTCGTAAAAGACGGACAAATCATTGCCGAAGCGGTGACCGCCATCGGCGGCCGGCCGC
ACGCCGAACGCCAGGCGCTGGAAATCGCCGGCGAGGCGGCGCGTGGCGCGACTGCCTATGTAACGCTCGAACCCTGTTCC
CACTGGGGCAAAACCCCGCCCTGCGCCAACGCGCTGGTCGAATACGGCGTGGCGCGGGTCGTGGTGGCGGTGGACGATCC
GGATGAGCGTGTTTCCGGCCGTGGTTATACGATTTTACGCGATGCCGGTATTGTTGTGGAAACAGGCCTGCTGCGTGATG
AGGGTAAGCGGGCGCTTGCAGGTTACCTCACACGTCAGATGAAAAAACGCCCGCATGTGATTCTGAAGCTTGCTGTTTCC
GCTGATGGCATGATTGGCCGGGAAGGCGAGGGGCAGGTGGCGATTACCGGGGCGGAGTCGCGCCGTGTGGTGCATGAACT
GCGGGCGCGCTGCGATGGCATTCTTGTCGGTATTCGTACCGCGATTGCGGATGATCCGGAACTGACGGTGCGCATTGCCG
GCATGGAGCGCCGCTCGCCGGTGCGGATCGTGCTGGATCGGCAGTTTGAGTTGCCGCTGATGTCGAAGCTTGTGCGGAGC
GCGCGCGAGGTGCCGGTGATCGTTGCGGCGTTACCCCCCTCTGCCCTGCCGGGCATCTCCCCCTCAAGGGGGGAGATCGG
CGAGGCGCTGTCCGCTCGCTCAAATTTTGAACCCGTTTCTCATTCTCCAGCCGTTGATGTTGGGCAAGACAGTGCCCCAT
CGATCCCCCCCCTTGAGGGGGAGATGCCCGGCAGGGCAGAGGGGGGTAACCCCAACCTCCGACGTCAACTCCTGACCGAC
GCAGGCGTCCAGATCCTCGAAGCATCAACCCTCGAAAACCTCCTCCACATTCTCGCCGAAAGCGGCATTTCGGAACTTCT
GGTCGAAGGCGGCGCTTTTGCCGCAAAATCATTCCTTGAAGCCGGGCTGGTGGACCGTATCATGCTGTTCGAAAGCCCTG
TCGTGATCGGCGAAGGCGGCATTGAAACGCCGCTTCGCCGTGCCGATATCACGGGCGACTATGCTCTTGTCAGCGAAACA
GCCTATGGGCCGGATCGCTGCTTCGATTATGAAAGGCCGATTTGA

Upstream 100 bases:

>100_bases
CTTCGGTCTATCGCGATTTCAGCCATGCCGAGGATTTCGAAAACGTGATTGCCGAAATCAACGCCAAGATCGCCCGAGAT
ACAGACGCCGGAGCATAGCC

Downstream 100 bases:

>100_bases
TGTTTACCGGAATTGTCACCGATGTCGGAACCGTATCCGAGCTGGAAGCGCTGCCGGAGGGTGTTCGCCTGCGCGTGGCG
ACCAATTACGATCCGAAGAC

Product: bifunctional riboflavin deaminase-reductase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MTSRADDEKFMARAIEVSLRHQGQTLTNPSVGCVLVKDGQIIAEAVTAIGGRPHAERQALEIAGEAARGATAYVTLEPCS
HWGKTPPCANALVEYGVARVVVAVDDPDERVSGRGYTILRDAGIVVETGLLRDEGKRALAGYLTRQMKKRPHVILKLAVS
ADGMIGREGEGQVAITGAESRRVVHELRARCDGILVGIRTAIADDPELTVRIAGMERRSPVRIVLDRQFELPLMSKLVRS
AREVPVIVAALPPSALPGISPSRGEIGEALSARSNFEPVSHSPAVDVGQDSAPSIPPLEGEMPGRAEGGNPNLRRQLLTD
AGVQILEASTLENLLHILAESGISELLVEGGAFAAKSFLEAGLVDRIMLFESPVVIGEGGIETPLRRADITGDYALVSET
AYGPDRCFDYERPI

Sequences:

>Translated_414_residues
MTSRADDEKFMARAIEVSLRHQGQTLTNPSVGCVLVKDGQIIAEAVTAIGGRPHAERQALEIAGEAARGATAYVTLEPCS
HWGKTPPCANALVEYGVARVVVAVDDPDERVSGRGYTILRDAGIVVETGLLRDEGKRALAGYLTRQMKKRPHVILKLAVS
ADGMIGREGEGQVAITGAESRRVVHELRARCDGILVGIRTAIADDPELTVRIAGMERRSPVRIVLDRQFELPLMSKLVRS
AREVPVIVAALPPSALPGISPSRGEIGEALSARSNFEPVSHSPAVDVGQDSAPSIPPLEGEMPGRAEGGNPNLRRQLLTD
AGVQILEASTLENLLHILAESGISELLVEGGAFAAKSFLEAGLVDRIMLFESPVVIGEGGIETPLRRADITGDYALVSET
AYGPDRCFDYERPI
>Mature_413_residues
TSRADDEKFMARAIEVSLRHQGQTLTNPSVGCVLVKDGQIIAEAVTAIGGRPHAERQALEIAGEAARGATAYVTLEPCSH
WGKTPPCANALVEYGVARVVVAVDDPDERVSGRGYTILRDAGIVVETGLLRDEGKRALAGYLTRQMKKRPHVILKLAVSA
DGMIGREGEGQVAITGAESRRVVHELRARCDGILVGIRTAIADDPELTVRIAGMERRSPVRIVLDRQFELPLMSKLVRSA
REVPVIVAALPPSALPGISPSRGEIGEALSARSNFEPVSHSPAVDVGQDSAPSIPPLEGEMPGRAEGGNPNLRRQLLTDA
GVQILEASTLENLLHILAESGISELLVEGGAFAAKSFLEAGLVDRIMLFESPVVIGEGGIETPLRRADITGDYALVSETA
YGPDRCFDYERPI

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=251, Percent_Identity=44.6215139442231, Blast_Score=199, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 44204; Mature: 44073

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00903 CYT_DCMP_DEAMINASES ; PS00878 ODR_DC_2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRADDEKFMARAIEVSLRHQGQTLTNPSVGCVLVKDGQIIAEAVTAIGGRPHAERQAL
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHH
EIAGEAARGATAYVTLEPCSHWGKTPPCANALVEYGVARVVVAVDDPDERVSGRGYTILR
HHHHHCCCCCEEEEEECCHHCCCCCCHHHHHHHHCCCEEEEEEECCCHHHHCCCCEEEEE
DAGIVVETGLLRDEGKRALAGYLTRQMKKRPHVILKLAVSADGMIGREGEGQVAITGAES
CCCEEEEECCCHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEECCHH
RRVVHELRARCDGILVGIRTAIADDPELTVRIAGMERRSPVRIVLDRQFELPLMSKLVRS
HHHHHHHHHHHCEEEEEEHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHH
AREVPVIVAALPPSALPGISPSRGEIGEALSARSNFEPVSHSPAVDVGQDSAPSIPPLEG
HCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EMPGRAEGGNPNLRRQLLTDAGVQILEASTLENLLHILAESGISELLVEGGAFAAKSFLE
CCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHH
AGLVDRIMLFESPVVIGEGGIETPLRRADITGDYALVSETAYGPDRCFDYERPI
HHHHHHHHHHCCCEEEECCCCCCCCHHHCCCCCEEEEECCCCCCHHCCCCCCCC
>Mature Secondary Structure 
TSRADDEKFMARAIEVSLRHQGQTLTNPSVGCVLVKDGQIIAEAVTAIGGRPHAERQAL
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHH
EIAGEAARGATAYVTLEPCSHWGKTPPCANALVEYGVARVVVAVDDPDERVSGRGYTILR
HHHHHCCCCCEEEEEECCHHCCCCCCHHHHHHHHCCCEEEEEEECCCHHHHCCCCEEEEE
DAGIVVETGLLRDEGKRALAGYLTRQMKKRPHVILKLAVSADGMIGREGEGQVAITGAES
CCCEEEEECCCHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEECCHH
RRVVHELRARCDGILVGIRTAIADDPELTVRIAGMERRSPVRIVLDRQFELPLMSKLVRS
HHHHHHHHHHHCEEEEEEHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHH
AREVPVIVAALPPSALPGISPSRGEIGEALSARSNFEPVSHSPAVDVGQDSAPSIPPLEG
HCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EMPGRAEGGNPNLRRQLLTDAGVQILEASTLENLLHILAESGISELLVEGGAFAAKSFLE
CCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHH
AGLVDRIMLFESPVVIGEGGIETPLRRADITGDYALVSETAYGPDRCFDYERPI
HHHHHHHHHHCCCEEEECCCCCCCCHHHCCCCCEEEEECCCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]