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The map label for this gene is rhtC [C]

Identifier: 15888507

GI number: 15888507

Start: 1164042

End: 1164674

Strand: Direct

Name: rhtC [C]

Synonym: Atu1170

Alternate gene names: 15888507

Gene position: 1164042-1164674 (Clockwise)

Preceding gene: 159184646

Following gene: 15888508

Centisome position: 40.96

GC content: 60.51

Gene sequence:

>633_bases
ATGCCGTCTTTTGAACTGCTGACAGCCTTTTTCATCACCACCGCCCTGTTTGCCTACATTCCCGGCCCAGCCATGCTTTA
TGCGGCGGCGCAGACTATGGCGCGTGGCCGGTTTGCCGGGCTGATGGCGGTGCTCGGCATCCATGTCGGCTGCTATTTTC
ACATTTTCGCGGCGGCTGCGGGCCTCTCGGTATTGTTTCAGGCGGTGCCCTGGCTTTACCTTGCAGTGAAGCTCTGCGGC
GCGCTTTATCTCATCTGGCTTGGGTTTTCGATGCTGCGCAGCAAACTGGAAGGCGAGGCGGTCAATCTGACCATCGAGCC
GAAATCGGCCCGCCGCGCCTTCATCGACAGCATCATCGTTGATGTGCTCAACCCGAAGACCGCGCTGTTCTTTCTGGCCT
TCCTGCCGCAATTCGTCGACCCGGCGGCGGCCTTTCCCGTCTGGCTACAGTTCCTGATCCTCGGCATTGCCGTCAATTTC
ATCTTCTCCTCCGCCGATCTCGTCGGCGTGCTTCTGGCGGGCGCCATGGTCCGGCGTCTGAAACGGTCCAGCGCCGTGCA
GGCTCTCGCCCGACGTGTCGCCGGAACGGTACTGATGGGGCTTGGTGTCCATCTGGCTTTCCAGAAAAGCTGA

Upstream 100 bases:

>100_bases
CGTGCAATTGCTCCGCTTCCTGTCGAACCGGAAAGATTGTAAAGACGTCGTTCTATCGTTTGAAATCGACTGCCAGCGAA
CGGGGTAGGGGAAATACATC

Downstream 100 bases:

>100_bases
TTTTTCAGCCTTGCCGCACAGACATTAAGCCTTGCAGCAGCTGGTGCAAACGGGTCATGCTGCGCGGGCAATGCACGAAA
ATACTTGCCAAGAACGGCCA

Product: RhtB family transporter

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MPSFELLTAFFITTALFAYIPGPAMLYAAAQTMARGRFAGLMAVLGIHVGCYFHIFAAAAGLSVLFQAVPWLYLAVKLCG
ALYLIWLGFSMLRSKLEGEAVNLTIEPKSARRAFIDSIIVDVLNPKTALFFLAFLPQFVDPAAAFPVWLQFLILGIAVNF
IFSSADLVGVLLAGAMVRRLKRSSAVQALARRVAGTVLMGLGVHLAFQKS

Sequences:

>Translated_210_residues
MPSFELLTAFFITTALFAYIPGPAMLYAAAQTMARGRFAGLMAVLGIHVGCYFHIFAAAAGLSVLFQAVPWLYLAVKLCG
ALYLIWLGFSMLRSKLEGEAVNLTIEPKSARRAFIDSIIVDVLNPKTALFFLAFLPQFVDPAAAFPVWLQFLILGIAVNF
IFSSADLVGVLLAGAMVRRLKRSSAVQALARRVAGTVLMGLGVHLAFQKS
>Mature_209_residues
PSFELLTAFFITTALFAYIPGPAMLYAAAQTMARGRFAGLMAVLGIHVGCYFHIFAAAAGLSVLFQAVPWLYLAVKLCGA
LYLIWLGFSMLRSKLEGEAVNLTIEPKSARRAFIDSIIVDVLNPKTALFFLAFLPQFVDPAAAFPVWLQFLILGIAVNFI
FSSADLVGVLLAGAMVRRLKRSSAVQALARRVAGTVLMGLGVHLAFQKS

Specific function: Conducts The Efflux Of Threonine. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=210, Percent_Identity=28.0952380952381, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1788099, Length=182, Percent_Identity=29.1208791208791, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI48994979, Length=156, Percent_Identity=27.5641025641026, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22720; Mature: 22588

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSFELLTAFFITTALFAYIPGPAMLYAAAQTMARGRFAGLMAVLGIHVGCYFHIFAAAA
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLSVLFQAVPWLYLAVKLCGALYLIWLGFSMLRSKLEGEAVNLTIEPKSARRAFIDSIIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHH
DVLNPKTALFFLAFLPQFVDPAAAFPVWLQFLILGIAVNFIFSSADLVGVLLAGAMVRRL
HHHCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRSSAVQALARRVAGTVLMGLGVHLAFQKS
HHHHHHHHHHHHHHHHHHHHHHHHHEEECC
>Mature Secondary Structure 
PSFELLTAFFITTALFAYIPGPAMLYAAAQTMARGRFAGLMAVLGIHVGCYFHIFAAAA
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLSVLFQAVPWLYLAVKLCGALYLIWLGFSMLRSKLEGEAVNLTIEPKSARRAFIDSIIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHH
DVLNPKTALFFLAFLPQFVDPAAAFPVWLQFLILGIAVNFIFSSADLVGVLLAGAMVRRL
HHHCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRSSAVQALARRVAGTVLMGLGVHLAFQKS
HHHHHHHHHHHHHHHHHHHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8169201; 10984043 [H]