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The map label for this gene is purC

Identifier: 15889807

GI number: 15889807

Start: 2519211

End: 2520161

Strand: Direct

Name: purC

Synonym: Atu2548

Alternate gene names: 15889807

Gene position: 2519211-2520161 (Clockwise)

Preceding gene: 159185262

Following gene: 15889808

Centisome position: 88.66

GC content: 56.68

Gene sequence:

>951_bases
GTGCGCATTCTTGATGAAGCCGTCATTCCCGAGCTGCCGAATTATTACCGCGGCAAGGTCCGGGAAAACTATGATCTGCC
CGACGGCAACCGTATCATCATATCCACCGATCGCCTGAGCGCCTTCGACCAAATCCTCACATGCATCCCTTATAAGGGAC
AGGTACTCACCCAGACGGCACGCTACTGGTTCGAACAGACAAAGGATATTTGCCCCAACCATGTGGTCAGCTATCCCGAC
CCGAATGTCGTCATCGGCAAGAGGCTGGATATATTGCCGGTCGAAGTGGTGGTCCGCGGTTATCTGGCTGGCACGACCGG
CACCTCGATCCTCACCCTCTATAAGAAGGGCGAACGGCAGATGTACGGCATGAGCCTACCTGACGGGATGAAGGACAACC
AGATTCTGCCCGAGCCGGTCATCACACCGACAAGCAAAGCCTTTGACGGCGGTCACGACGAGCCGCTGACGCCCTCCGAG
ATCGTGGAGAAGAAACTCCTGACGCAGGAGCAGTGGGATACGCTGTCCCGTTATGCGCTGGCGCTGTTCAGGCACGGTCA
AGAGATTGCGGCAAAGCAGGGTCTTATTCTCGTCGATACGAAATATGAATTCGGCACCGATGAAAATGGCACGATCATTC
TGGCCGACGAAATCCACACACCTGACAGCAGCCGTTACTGGATGGCTGACAGCTATGACGAGAGCTTCCGCGAGGGAAAG
CGGCCGGCGAGCTTCGACAAGGATTTCGTGAGAGCCTGGGTTGGCGAACGCTGCGATCCCTACAAGGACGCCGTTCCCAA
AATTCCTGAGGATCTCGTCCTGCAGACCTCGCAGGTCTATATTGATGCTTATGAACGCATCACCGGACAGCGCTTCGTTC
CCGACGATAGCGGCGAGACGCCGTTGGCGAGAGTACGCCGGAATCTGGAGCCGTTCTTCCCCGGAGTCTGA

Upstream 100 bases:

>100_bases
GACTGGCCCTGCTCCGGGAAACATGCAATAGGAACGGATAGGAGTTTCAGTCAGATCGGGGCGTCCCACGCCCCTTATAA
AGCCAAGAATTGGAGAGCCC

Downstream 100 bases:

>100_bases
CCCGTGAACAAAACGATTGATCAGGTGAGAAAGGGCGACAGGAAAAGTGACCTTCCCGTGCGGCGCCGGCCTCGCCGTTC
CGCCGAGGAAACCCGGCGGG

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase 2

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MRILDEAVIPELPNYYRGKVRENYDLPDGNRIIISTDRLSAFDQILTCIPYKGQVLTQTARYWFEQTKDICPNHVVSYPD
PNVVIGKRLDILPVEVVVRGYLAGTTGTSILTLYKKGERQMYGMSLPDGMKDNQILPEPVITPTSKAFDGGHDEPLTPSE
IVEKKLLTQEQWDTLSRYALALFRHGQEIAAKQGLILVDTKYEFGTDENGTIILADEIHTPDSSRYWMADSYDESFREGK
RPASFDKDFVRAWVGERCDPYKDAVPKIPEDLVLQTSQVYIDAYERITGQRFVPDDSGETPLARVRRNLEPFFPGV

Sequences:

>Translated_316_residues
MRILDEAVIPELPNYYRGKVRENYDLPDGNRIIISTDRLSAFDQILTCIPYKGQVLTQTARYWFEQTKDICPNHVVSYPD
PNVVIGKRLDILPVEVVVRGYLAGTTGTSILTLYKKGERQMYGMSLPDGMKDNQILPEPVITPTSKAFDGGHDEPLTPSE
IVEKKLLTQEQWDTLSRYALALFRHGQEIAAKQGLILVDTKYEFGTDENGTIILADEIHTPDSSRYWMADSYDESFREGK
RPASFDKDFVRAWVGERCDPYKDAVPKIPEDLVLQTSQVYIDAYERITGQRFVPDDSGETPLARVRRNLEPFFPGV
>Mature_316_residues
MRILDEAVIPELPNYYRGKVRENYDLPDGNRIIISTDRLSAFDQILTCIPYKGQVLTQTARYWFEQTKDICPNHVVSYPD
PNVVIGKRLDILPVEVVVRGYLAGTTGTSILTLYKKGERQMYGMSLPDGMKDNQILPEPVITPTSKAFDGGHDEPLTPSE
IVEKKLLTQEQWDTLSRYALALFRHGQEIAAKQGLILVDTKYEFGTDENGTIILADEIHTPDSSRYWMADSYDESFREGK
RPASFDKDFVRAWVGERCDPYKDAVPKIPEDLVLQTSQVYIDAYERITGQRFVPDDSGETPLARVRRNLEPFFPGV

Specific function: Unknown

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=306, Percent_Identity=35.2941176470588, Blast_Score=175, Evalue=8e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PUR72_AGRT5 (Q8UCE7)

Other databases:

- EMBL:   AE007869
- PIR:   AC2889
- PIR:   H97664
- RefSeq:   NP_355488.1
- ProteinModelPortal:   Q8UCE7
- SMR:   Q8UCE7
- STRING:   Q8UCE7
- GeneID:   1134586
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu2548
- eggNOG:   COG0152
- HOGENOM:   HBG555040
- OMA:   LTLMDEV
- PhylomeDB:   Q8UCE7
- ProtClustDB:   PRK12607
- BioCyc:   ATUM176299-1:ATU2548-MONOMER
- HAMAP:   MF_00137
- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236
- Gene3D:   G3DSA:3.30.470.20
- PANTHER:   PTHR11609

Pfam domain/function: PF01259 SAICAR_synt

EC number: =6.3.2.6

Molecular weight: Translated: 35975; Mature: 35975

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS01057 SAICAR_SYNTHETASE_1; PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILDEAVIPELPNYYRGKVRENYDLPDGNRIIISTDRLSAFDQILTCIPYKGQVLTQTA
CCCCHHHHCCCCCHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCHHHHHHH
RYWFEQTKDICPNHVVSYPDPNVVIGKRLDILPVEVVVRGYLAGTTGTSILTLYKKGERQ
HHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCE
MYGMSLPDGMKDNQILPEPVITPTSKAFDGGHDEPLTPSEIVEKKLLTQEQWDTLSRYAL
EECCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ALFRHGQEIAAKQGLILVDTKYEFGTDENGTIILADEIHTPDSSRYWMADSYDESFREGK
HHHHCCHHHHHHCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEEECCCHHHHHHCCC
RPASFDKDFVRAWVGERCDPYKDAVPKIPEDLVLQTSQVYIDAYERITGQRFVPDDSGET
CCCCCCHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PLARVRRNLEPFFPGV
HHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRILDEAVIPELPNYYRGKVRENYDLPDGNRIIISTDRLSAFDQILTCIPYKGQVLTQTA
CCCCHHHHCCCCCHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCHHHHHHH
RYWFEQTKDICPNHVVSYPDPNVVIGKRLDILPVEVVVRGYLAGTTGTSILTLYKKGERQ
HHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCE
MYGMSLPDGMKDNQILPEPVITPTSKAFDGGHDEPLTPSEIVEKKLLTQEQWDTLSRYAL
EECCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ALFRHGQEIAAKQGLILVDTKYEFGTDENGTIILADEIHTPDSSRYWMADSYDESFREGK
HHHHCCHHHHHHCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEEECCCHHHHHHCCC
RPASFDKDFVRAWVGERCDPYKDAVPKIPEDLVLQTSQVYIDAYERITGQRFVPDDSGET
CCCCCCHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PLARVRRNLEPFFPGV
HHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194