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The map label for this gene is dppC [H]

Identifier: 15889781

GI number: 15889781

Start: 2484631

End: 2485533

Strand: Reverse

Name: dppC [H]

Synonym: Atu2516

Alternate gene names: 15889781

Gene position: 2485533-2484631 (Counterclockwise)

Preceding gene: 15889782

Following gene: 15889780

Centisome position: 87.47

GC content: 62.46

Gene sequence:

>903_bases
ATGATGTTAGCTAATTTCAGAAACTGGGCGCTGGACGAGACGCCGCATTCCCGCACACAGGCTGCGTGGGGAAACCGGTA
TCGCATCTGGCTCAACCTCAAGTCCAATCCGCTGGCAGTGATCGGTCTGACGATCATCGTCCTCTTCATCGCGTTGTCGC
TACTGGCGCCCGCCATCGCGCCTTATGATCCGGCAACGCAGAATCTCGGCAATCGCTTAGCATTTCCAAATGCAGAACAC
TGGTTCGGCACGGATGAGCTGGGTCGCGATATTCTCTCGCGCATCCTCTATGGCGGCCGCGTCACGCTCGGCATGGTCAT
CGCCGTCGTCGTTCTCGTCGCACCCATCGGCCTCGCCATCGGCTGCATCGCCGGTTATTTCGGCGGCATCGTCGATACCG
TGCTGATGCGGGTGACGGATGTGTTTCTGGCTTTTCCGCGCCTCATTCTGGCGCTGGCCTTCGTTGCGGCGCTGAAGCCC
GGCGTCGAAAGCGCCATTCTCGCCATCGCGCTTACGGCATGGCCGCCCTATGCGCGTCTTGCCCGCGCCGAAACCATGAC
GGTTCGCGGCAGCGACTTCGTGGCGGCCTACCGGCTGACCGGCGCCTCCGCCTGGCGCATCATCGCCCGTCACATCGCGC
CGCTCTGCGTGCCGAGCCTTATCGTGCGCATCACGCTCGACATGAGCTCGATCATCATCACCGCCGCCAGTCTCGGCTTC
CTTGGCATGGGCGCGCAGCCGCCGTCGCCGGAATGGGGTGCGATGATTGCCACCGCCAAGCGCTTCATCTTCGAACAATG
GTGGGTCGCCACCATTCCCGGCATCGCCATCTTCCTCGTCTCGCTCGCCTTCAACTTCCTCGGCGATGGCCTGCGTGACG
TTCTCGACCCGAAGGGACATTGA

Upstream 100 bases:

>100_bases
TGAACCCCGTCGTCGGAGCAACCCTGTTGATCGGCATTATCTATGTCGGCCTCAACCTGCTTGCAGACGTGCTTTACCGA
GTAATGGATCCCCGCGTTCG

Downstream 100 bases:

>100_bases
GCCATGCTGGTCGAAATCGAAAATCTGAAGATCGCTTTCCAGACCCGCACCAGCCGCTTCGAGGCGGTGCGCGGTGTGTC
CATGAAGCTCGGCACCGAAA

Product: ABC transporter, membrane spanning protein (dipeptide)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MMLANFRNWALDETPHSRTQAAWGNRYRIWLNLKSNPLAVIGLTIIVLFIALSLLAPAIAPYDPATQNLGNRLAFPNAEH
WFGTDELGRDILSRILYGGRVTLGMVIAVVVLVAPIGLAIGCIAGYFGGIVDTVLMRVTDVFLAFPRLILALAFVAALKP
GVESAILAIALTAWPPYARLARAETMTVRGSDFVAAYRLTGASAWRIIARHIAPLCVPSLIVRITLDMSSIIITAASLGF
LGMGAQPPSPEWGAMIATAKRFIFEQWWVATIPGIAIFLVSLAFNFLGDGLRDVLDPKGH

Sequences:

>Translated_300_residues
MMLANFRNWALDETPHSRTQAAWGNRYRIWLNLKSNPLAVIGLTIIVLFIALSLLAPAIAPYDPATQNLGNRLAFPNAEH
WFGTDELGRDILSRILYGGRVTLGMVIAVVVLVAPIGLAIGCIAGYFGGIVDTVLMRVTDVFLAFPRLILALAFVAALKP
GVESAILAIALTAWPPYARLARAETMTVRGSDFVAAYRLTGASAWRIIARHIAPLCVPSLIVRITLDMSSIIITAASLGF
LGMGAQPPSPEWGAMIATAKRFIFEQWWVATIPGIAIFLVSLAFNFLGDGLRDVLDPKGH
>Mature_300_residues
MMLANFRNWALDETPHSRTQAAWGNRYRIWLNLKSNPLAVIGLTIIVLFIALSLLAPAIAPYDPATQNLGNRLAFPNAEH
WFGTDELGRDILSRILYGGRVTLGMVIAVVVLVAPIGLAIGCIAGYFGGIVDTVLMRVTDVFLAFPRLILALAFVAALKP
GVESAILAIALTAWPPYARLARAETMTVRGSDFVAAYRLTGASAWRIIARHIAPLCVPSLIVRITLDMSSIIITAASLGF
LGMGAQPPSPEWGAMIATAKRFIFEQWWVATIPGIAIFLVSLAFNFLGDGLRDVLDPKGH

Specific function: Part of the ABC transporter complex ddpABCDF, which is probably involved in D,D-dipeptide transport. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=289, Percent_Identity=43.2525951557093, Blast_Score=246, Evalue=1e-66,
Organism=Escherichia coli, GI1787054, Length=303, Percent_Identity=41.2541254125413, Blast_Score=222, Evalue=2e-59,
Organism=Escherichia coli, GI1789964, Length=277, Percent_Identity=46.9314079422383, Blast_Score=204, Evalue=4e-54,
Organism=Escherichia coli, GI1789889, Length=238, Percent_Identity=45.3781512605042, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1787498, Length=303, Percent_Identity=30.03300330033, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1787549, Length=275, Percent_Identity=35.2727272727273, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1788505, Length=224, Percent_Identity=29.9107142857143, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32462; Mature: 32462

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLANFRNWALDETPHSRTQAAWGNRYRIWLNLKSNPLAVIGLTIIVLFIALSLLAPAIA
CCCCCCCCCCCCCCCCCHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
PYDPATQNLGNRLAFPNAEHWFGTDELGRDILSRILYGGRVTLGMVIAVVVLVAPIGLAI
CCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
GCIAGYFGGIVDTVLMRVTDVFLAFPRLILALAFVAALKPGVESAILAIALTAWPPYARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHH
ARAETMTVRGSDFVAAYRLTGASAWRIIARHIAPLCVPSLIVRITLDMSSIIITAASLGF
HHHHHEEECCCCCEEEHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGMGAQPPSPEWGAMIATAKRFIFEQWWVATIPGIAIFLVSLAFNFLGDGLRDVLDPKGH
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MMLANFRNWALDETPHSRTQAAWGNRYRIWLNLKSNPLAVIGLTIIVLFIALSLLAPAIA
CCCCCCCCCCCCCCCCCHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
PYDPATQNLGNRLAFPNAEHWFGTDELGRDILSRILYGGRVTLGMVIAVVVLVAPIGLAI
CCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
GCIAGYFGGIVDTVLMRVTDVFLAFPRLILALAFVAALKPGVESAILAIALTAWPPYARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHH
ARAETMTVRGSDFVAAYRLTGASAWRIIARHIAPLCVPSLIVRITLDMSSIIITAASLGF
HHHHHEEECCCCCEEEHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGMGAQPPSPEWGAMIATAKRFIFEQWWVATIPGIAIFLVSLAFNFLGDGLRDVLDPKGH
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]