| Definition | Agrobacterium tumefaciens str. C58 chromosome circular, complete sequence. |
|---|---|
| Accession | NC_003062 |
| Length | 2,841,580 |
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The map label for this gene is gdhII [H]
Identifier: 15889329
GI number: 15889329
Start: 2000568
End: 2001317
Strand: Reverse
Name: gdhII [H]
Synonym: Atu2042
Alternate gene names: 15889329
Gene position: 2001317-2000568 (Counterclockwise)
Preceding gene: 159185024
Following gene: 159185023
Centisome position: 70.43
GC content: 62.8
Gene sequence:
>750_bases ATGAAATTACTCGAAAACAAGGTTGCTATCATCACCGGCGCGTCATCCGGCATCGGCCGGGCGACGGCGATGCTGTTTGT CACGCAAGGCGCGGCAGTCGTCATCAATGCGCGCGGTGAAAAGGCGCTGCAGGAGGTTGCAGCCGACATTCGTGATGCCG GCGGCCGTGTCCATGCGGTTGCGGGCGACGCCGGTGTTGCGGAAACCCATTCCCGGTTGGCGGATGCGGCCGTGGGCGTT TTCGGTGGCCTCGATATCGCCATCAATAATGCCGGGGCGGTGGGGGCTATGAAGCCGCTGGCGGAGATTTCGCCCGAGGA GTGGGATCATGTCCTCAACGTCAATCTCACCTCCGCCTTTCTGGGGGCGCGTTACCAGATTCCGCCGATGCTGAAGCGGG GCGGCGGTTCCATCGTCTTTACGTCGAGCTTCGTCGGCACCAGCGCCGGCATTCCTGGCATGTCGGCTTATGGAACTGCG AAGGCAGCGTTAATGGGGCTGGTGAAGGGCATTACCGCCGATTATGCGATCAATGGCATTCGCGCCAATGCCCTGCTCCC CGGCGGGGTCGATACACCGGCCGCAGGAGACCCGGCGCAGAAGGAATGGGCCGCCGGCCTGCATGCGATGAAGCGCATTG CCCAGCCCGAGGAAATTGCGCAGGCCGCTCTTTTCCTCGCAAGCCCAATGGCAAGCTTCGTCGCCGGGGCCGCATTGTTT GCCGATGGCGGCAATGCCGCGGTGAAATGA
Upstream 100 bases:
>100_bases CGCTGGAATAAACGCTTTTCGCCCGATCCGTCAGGAATCGGGTGGTTGCGGCACTGTCGGGTCCCTATCCCTTGGTCTCC ATCAAACGGAGGCCAAGGAT
Downstream 100 bases:
>100_bases CTTTCGGAACTGACGGGCAGGCGTTTTATCGCGCCCGCCATTCCTCCAGCGTCAGCGCATAGGTGACGTGGGGCCGCAGA TGCGGGTGCGTCTCTTCCGG
Product: short chain dehydrogenase
Products: NA
Alternate protein names: GLCDH-II [H]
Number of amino acids: Translated: 249; Mature: 249
Protein sequence:
>249_residues MKLLENKVAIITGASSGIGRATAMLFVTQGAAVVINARGEKALQEVAADIRDAGGRVHAVAGDAGVAETHSRLADAAVGV FGGLDIAINNAGAVGAMKPLAEISPEEWDHVLNVNLTSAFLGARYQIPPMLKRGGGSIVFTSSFVGTSAGIPGMSAYGTA KAALMGLVKGITADYAINGIRANALLPGGVDTPAAGDPAQKEWAAGLHAMKRIAQPEEIAQAALFLASPMASFVAGAALF ADGGNAAVK
Sequences:
>Translated_249_residues MKLLENKVAIITGASSGIGRATAMLFVTQGAAVVINARGEKALQEVAADIRDAGGRVHAVAGDAGVAETHSRLADAAVGV FGGLDIAINNAGAVGAMKPLAEISPEEWDHVLNVNLTSAFLGARYQIPPMLKRGGGSIVFTSSFVGTSAGIPGMSAYGTA KAALMGLVKGITADYAINGIRANALLPGGVDTPAAGDPAQKEWAAGLHAMKRIAQPEEIAQAALFLASPMASFVAGAALF ADGGNAAVK >Mature_249_residues MKLLENKVAIITGASSGIGRATAMLFVTQGAAVVINARGEKALQEVAADIRDAGGRVHAVAGDAGVAETHSRLADAAVGV FGGLDIAINNAGAVGAMKPLAEISPEEWDHVLNVNLTSAFLGARYQIPPMLKRGGGSIVFTSSFVGTSAGIPGMSAYGTA KAALMGLVKGITADYAINGIRANALLPGGVDTPAAGDPAQKEWAAGLHAMKRIAQPEEIAQAALFLASPMASFVAGAALF ADGGNAAVK
Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=33.3333333333333, Blast_Score=137, Evalue=1e-32, Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=31.3725490196078, Blast_Score=115, Evalue=5e-26, Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=35.1648351648352, Blast_Score=108, Evalue=4e-24, Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=30.1204819277108, Blast_Score=105, Evalue=3e-23, Organism=Homo sapiens, GI5031737, Length=238, Percent_Identity=30.2521008403361, Blast_Score=105, Evalue=3e-23, Organism=Homo sapiens, GI66933014, Length=252, Percent_Identity=32.9365079365079, Blast_Score=105, Evalue=3e-23, Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=30.6451612903226, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI210032110, Length=200, Percent_Identity=29.5, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=30.5263157894737, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI4504505, Length=193, Percent_Identity=32.6424870466321, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=28.740157480315, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI142976729, Length=238, Percent_Identity=27.3109243697479, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=28.3333333333333, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI7705925, Length=247, Percent_Identity=29.5546558704453, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI40807363, Length=232, Percent_Identity=28.0172413793103, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI32455239, Length=203, Percent_Identity=32.512315270936, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI5031765, Length=203, Percent_Identity=32.512315270936, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI109715829, Length=245, Percent_Identity=29.7959183673469, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI302344755, Length=109, Percent_Identity=37.6146788990826, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI226371731, Length=199, Percent_Identity=30.6532663316583, Blast_Score=74, Evalue=8e-14, Organism=Homo sapiens, GI4503301, Length=256, Percent_Identity=30.078125, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=28.695652173913, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI209862901, Length=208, Percent_Identity=29.8076923076923, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI19923983, Length=208, Percent_Identity=29.8076923076923, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI20149619, Length=204, Percent_Identity=27.9411764705882, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI4503817, Length=219, Percent_Identity=23.7442922374429, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI31542939, Length=209, Percent_Identity=29.1866028708134, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI31543615, Length=221, Percent_Identity=27.6018099547511, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=35.655737704918, Blast_Score=117, Evalue=9e-28, Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=33.2046332046332, Blast_Score=115, Evalue=3e-27, Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=32.6530612244898, Blast_Score=103, Evalue=7e-24, Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=8e-24, Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=30.7053941908714, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1787526, Length=193, Percent_Identity=34.7150259067358, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI2367365, Length=252, Percent_Identity=34.1269841269841, Blast_Score=100, Evalue=6e-23, Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=30.4347826086957, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1789378, Length=237, Percent_Identity=31.2236286919831, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=32.1428571428571, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=28.9156626506024, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=28.1632653061224, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI1787820, Length=227, Percent_Identity=22.9074889867841, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1786701, Length=187, Percent_Identity=28.3422459893048, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=31.3492063492063, Blast_Score=128, Evalue=3e-30, Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=30.6451612903226, Blast_Score=122, Evalue=1e-28, Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=34.5864661654135, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=33.4586466165414, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=33.955223880597, Blast_Score=112, Evalue=1e-25, Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=34.6774193548387, Blast_Score=110, Evalue=5e-25, Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=32.4427480916031, Blast_Score=110, Evalue=5e-25, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=34.5381526104418, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=31.8352059925094, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=32.8358208955224, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=33.4586466165414, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=30.1526717557252, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=30.8550185873606, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=31.0606060606061, Blast_Score=102, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=32.2448979591837, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=32.9588014981273, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562990, Length=270, Percent_Identity=31.1111111111111, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17544670, Length=259, Percent_Identity=27.7992277992278, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=31.4606741573034, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI25147288, Length=259, Percent_Identity=31.2741312741313, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=31.2267657992565, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=32.5670498084291, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=30.6201550387597, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=27.4436090225564, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17568967, Length=193, Percent_Identity=33.160621761658, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17508895, Length=246, Percent_Identity=25.609756097561, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17564282, Length=194, Percent_Identity=29.3814432989691, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17508651, Length=247, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17536025, Length=259, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=28.2258064516129, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17536651, Length=259, Percent_Identity=29.3436293436293, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI32563809, Length=225, Percent_Identity=27.1111111111111, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17507613, Length=225, Percent_Identity=27.1111111111111, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI86565303, Length=268, Percent_Identity=26.4925373134328, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17561272, Length=259, Percent_Identity=29.3436293436293, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI193203115, Length=234, Percent_Identity=26.4957264957265, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI193203117, Length=234, Percent_Identity=26.4957264957265, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17567345, Length=196, Percent_Identity=30.1020408163265, Blast_Score=66, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=193, Percent_Identity=31.0880829015544, Blast_Score=84, Evalue=2e-17, Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=29.7619047619048, Blast_Score=84, Evalue=2e-17, Organism=Saccharomyces cerevisiae, GI6322226, Length=190, Percent_Identity=31.0526315789474, Blast_Score=64, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=194, Percent_Identity=27.319587628866, Blast_Score=62, Evalue=8e-11, Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=33.4661354581673, Blast_Score=129, Evalue=2e-30, Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=32.9411764705882, Blast_Score=108, Evalue=4e-24, Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=32.520325203252, Blast_Score=106, Evalue=1e-23, Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=33.4630350194552, Blast_Score=105, Evalue=2e-23, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=34.136546184739, Blast_Score=105, Evalue=2e-23, Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=33.4630350194552, Blast_Score=104, Evalue=4e-23, Organism=Drosophila melanogaster, GI18859837, Length=192, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24644337, Length=251, Percent_Identity=34.2629482071713, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=30.8943089430894, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI24641232, Length=243, Percent_Identity=28.8065843621399, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI281364892, Length=200, Percent_Identity=28, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=30.5699481865285, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI17737361, Length=233, Percent_Identity=29.6137339055794, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI21357673, Length=228, Percent_Identity=28.9473684210526, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24640492, Length=199, Percent_Identity=25.6281407035176, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI28571387, Length=254, Percent_Identity=29.5275590551181, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI21356301, Length=193, Percent_Identity=30.0518134715026, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.47 [H]
Molecular weight: Translated: 24974; Mature: 24974
Theoretical pI: Translated: 6.97; Mature: 6.97
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 3.2 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKLLENKVAIITGASSGIGRATAMLFVTQGAAVVINARGEKALQEVAADIRDAGGRVHAV CCCCCCCEEEEECCCCCCCHHEEEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCEEEEE AGDAGVAETHSRLADAAVGVFGGLDIAINNAGAVGAMKPLAEISPEEWDHVLNVNLTSAF ECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCHHHHHHEEECCHHHHH LGARYQIPPMLKRGGGSIVFTSSFVGTSAGIPGMSAYGTAKAALMGLVKGITADYAINGI HCCCCCCCHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCE RANALLPGGVDTPAAGDPAQKEWAAGLHAMKRIAQPEEIAQAALFLASPMASFVAGAALF EECEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEE ADGGNAAVK ECCCCCCCC >Mature Secondary Structure MKLLENKVAIITGASSGIGRATAMLFVTQGAAVVINARGEKALQEVAADIRDAGGRVHAV CCCCCCCEEEEECCCCCCCHHEEEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCEEEEE AGDAGVAETHSRLADAAVGVFGGLDIAINNAGAVGAMKPLAEISPEEWDHVLNVNLTSAF ECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCHHHHHHEEECCHHHHH LGARYQIPPMLKRGGGSIVFTSSFVGTSAGIPGMSAYGTAKAALMGLVKGITADYAINGI HCCCCCCCHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCE RANALLPGGVDTPAAGDPAQKEWAAGLHAMKRIAQPEEIAQAALFLASPMASFVAGAALF EECEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEE ADGGNAAVK ECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA