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The map label for this gene is ilvH [H]

Identifier: 15889323

GI number: 15889323

Start: 1993415

End: 1993987

Strand: Reverse

Name: ilvH [H]

Synonym: Atu2035

Alternate gene names: 15889323

Gene position: 1993987-1993415 (Counterclockwise)

Preceding gene: 159185021

Following gene: 159185020

Centisome position: 70.17

GC content: 60.91

Gene sequence:

>573_bases
ATGAACGCACACCTACAACCCACCGGCTCCGCCTATTTCATCCAGAAGGAAACGGCTGCCGTTGAAAATCACACGCTGTC
GGTTCTCGTCAGCAACGAGCCGGGCGTTCTCGCCCGGGTCATCGGCCTGTTTTCCGGCCGTGGCTACAACATCGAAAGCC
TGACGGTTTCGGAAACGGAACATGAGGCGCATCTGTCGCGCATCACCATCGTCACACGGGGTACGCCCATCGTGCTGGAG
CAGATCAAGGCGCAGCTGGAACGCATCGTGCCGGTGCACCGGGTTCTGGACCTTACCGTCCGTGCCCGTGAACTGGGACA
GGAACGGCCGATCGAGCGCGAAGTGGCGCTCATCAAGGTTGCCGGCACGGGCGAAGTCCGTGCCGAGGCGCTGCGGCTTG
CCGATGCGTTTCAGGCCAAGGTGGTAGATGCCACGGTGGAGCATTTCATCTTCGAGATCACCGGCAAGTCATCCAAGATC
GACCAGTTCGTGGCGATCATCAAGCCGCTCGGCCTGATCGAAATCTGCCGCACGGGCATTGCCGCCATGAACCGCGGTTC
GCAGGGCATGTAA

Upstream 100 bases:

>100_bases
AACGAGATGCTGTTGCCGGATGAGGCGACGGATGAAGCTGTTGCCAACGCCATCGATGCCAAGGGCCGTCAGCTAGTCTG
AGCCGGGAGAGGAAAAGGAC

Downstream 100 bases:

>100_bases
TTCGTCTCTAAGCGAAATCTTCCATAAAGCCCGCGGTTCGCCGCGGGTTTTTTTATGGAATCCGCTTGGGATCGATATTC
AACCATGTGGTTGACATTCC

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MNAHLQPTGSAYFIQKETAAVENHTLSVLVSNEPGVLARVIGLFSGRGYNIESLTVSETEHEAHLSRITIVTRGTPIVLE
QIKAQLERIVPVHRVLDLTVRARELGQERPIEREVALIKVAGTGEVRAEALRLADAFQAKVVDATVEHFIFEITGKSSKI
DQFVAIIKPLGLIEICRTGIAAMNRGSQGM

Sequences:

>Translated_190_residues
MNAHLQPTGSAYFIQKETAAVENHTLSVLVSNEPGVLARVIGLFSGRGYNIESLTVSETEHEAHLSRITIVTRGTPIVLE
QIKAQLERIVPVHRVLDLTVRARELGQERPIEREVALIKVAGTGEVRAEALRLADAFQAKVVDATVEHFIFEITGKSSKI
DQFVAIIKPLGLIEICRTGIAAMNRGSQGM
>Mature_190_residues
MNAHLQPTGSAYFIQKETAAVENHTLSVLVSNEPGVLARVIGLFSGRGYNIESLTVSETEHEAHLSRITIVTRGTPIVLE
QIKAQLERIVPVHRVLDLTVRARELGQERPIEREVALIKVAGTGEVRAEALRLADAFQAKVVDATVEHFIFEITGKSSKI
DQFVAIIKPLGLIEICRTGIAAMNRGSQGM

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=166, Percent_Identity=43.9759036144578, Blast_Score=128, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6319837, Length=213, Percent_Identity=31.4553990610329, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 20772; Mature: 20772

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAHLQPTGSAYFIQKETAAVENHTLSVLVSNEPGVLARVIGLFSGRGYNIESLTVSETE
CCCCCCCCCCEEEEECCHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCH
HEAHLSRITIVTRGTPIVLEQIKAQLERIVPVHRVLDLTVRARELGQERPIEREVALIKV
HHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEE
AGTGEVRAEALRLADAFQAKVVDATVEHFIFEITGKSSKIDQFVAIIKPLGLIEICRTGI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCHHHHHHHHHH
AAMNRGSQGM
HHHCCCCCCC
>Mature Secondary Structure
MNAHLQPTGSAYFIQKETAAVENHTLSVLVSNEPGVLARVIGLFSGRGYNIESLTVSETE
CCCCCCCCCCEEEEECCHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCH
HEAHLSRITIVTRGTPIVLEQIKAQLERIVPVHRVLDLTVRARELGQERPIEREVALIKV
HHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEE
AGTGEVRAEALRLADAFQAKVVDATVEHFIFEITGKSSKIDQFVAIIKPLGLIEICRTGI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCHHHHHHHHHH
AAMNRGSQGM
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]