Click here to switch to the map view.

The map label for this gene is hupA [C]

Identifier: 15888591

GI number: 15888591

Start: 1251588

End: 1251863

Strand: Direct

Name: hupA [C]

Synonym: Atu1262

Alternate gene names: 15888591

Gene position: 1251588-1251863 (Clockwise)

Preceding gene: 15888590

Following gene: 159184688

Centisome position: 44.05

GC content: 58.7

Gene sequence:

>276_bases
ATGAACAAGAACGAGCTCGTCTCTGCTGTTGCCGAAAAGGCTGGTCTCACGAAGGCAGATGCTGCTTCCGCTGTTGATGC
CGTATTCGAAACCGTACAGGGCGAACTGAAGAACGGTGGCGACATCCGTCTCGCCGGCTTCGGCAGCTTCTCCGTAAGCC
GTCGTGAAGCCTCCAAGGGCCGTAACCCTTCCACGGGTGCTGAAGTCGATATCCCGGCTCGCAACGTGCCGAAGTTCTCC
GCAGGCAAGGGCCTGAAGGACGCCGTCAACTCGTAA

Upstream 100 bases:

>100_bases
TCAGGCGATTCCAGCGCTTTTGAGTTGCTGTGCGCGGATGCAAATGTATTCTGCGCCGGCTTAATTTTAGTCGTTTCAAA
CCATTGAAAGGGGTGGAAAC

Downstream 100 bases:

>100_bases
GGTTTCCGGAAAGTTGCGATGTCCGGCGGCGGGCATGCGGCTTTTTCAGGCTCACGAGGAAACATGTTTTGACGCGCTCA
TGCCATTATCAGGTGTGAGG

Product: histone-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 91; Mature: 91

Protein sequence:

>91_residues
MNKNELVSAVAEKAGLTKADAASAVDAVFETVQGELKNGGDIRLAGFGSFSVSRREASKGRNPSTGAEVDIPARNVPKFS
AGKGLKDAVNS

Sequences:

>Translated_91_residues
MNKNELVSAVAEKAGLTKADAASAVDAVFETVQGELKNGGDIRLAGFGSFSVSRREASKGRNPSTGAEVDIPARNVPKFS
AGKGLKDAVNS
>Mature_91_residues
MNKNELVSAVAEKAGLTKADAASAVDAVFETVQGELKNGGDIRLAGFGSFSVSRREASKGRNPSTGAEVDIPARNVPKFS
AGKGLKDAVNS

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=51.1111111111111, Blast_Score=92, Evalue=7e-21,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=47.1910112359551, Blast_Score=89, Evalue=5e-20,
Organism=Escherichia coli, GI1788005, Length=91, Percent_Identity=37.3626373626374, Blast_Score=70, Evalue=2e-14,
Organism=Escherichia coli, GI1787141, Length=91, Percent_Identity=36.2637362637363, Blast_Score=64, Evalue=2e-12,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9335; Mature: 9335

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNELVSAVAEKAGLTKADAASAVDAVFETVQGELKNGGDIRLAGFGSFSVSRREASKG
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHCC
RNPSTGAEVDIPARNVPKFSAGKGLKDAVNS
CCCCCCCEEECCCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MNKNELVSAVAEKAGLTKADAASAVDAVFETVQGELKNGGDIRLAGFGSFSVSRREASKG
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHCC
RNPSTGAEVDIPARNVPKFSAGKGLKDAVNS
CCCCCCCEEECCCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 4038648 [H]