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The map label for this gene is cya [H]

Identifier: 15888487

GI number: 15888487

Start: 1140111

End: 1141139

Strand: Reverse

Name: cya [H]

Synonym: Atu1149

Alternate gene names: 15888487

Gene position: 1141139-1140111 (Counterclockwise)

Preceding gene: 15888488

Following gene: 159184638

Centisome position: 40.16

GC content: 60.84

Gene sequence:

>1029_bases
ATGAGAAAATTGCTGCCCATTCTGGATTACGTGGTGCTCTTCGTTGCCGTGGCCGGCGCCGGGGTGGCCTACGCCTTTCT
GGAATATGGCGGCGGCGCGTTGATCGGCGCGACCTATGCGCTTTTCGCCTGCGCACCGATTCTCGCCTTTGAGCGCGGTT
ACATCTTGCCCGGCCTGTCGCGGCAGGTGAGCGCCTTGCCGACACCGGCCTATATCGCCGTCGGCCTCATCATCTATGCC
ATTCTCGTCTTCTGCGGCTTCGGGCTCGGTGGCACGATCCTGTGGCTCAGCGGGATATTTCCCGGCACCTGGAAACGGGC
GGTGCATGCCGAAGTGCAGACGCTGATCTTCACGCTTATCGTCTGCGGCATCATCGTCTTCATCATGCGCGTGCGCGAGC
TTCTCGGTCGCGATATCTTCATCGACCTCATTCTTGGGCGCTATCGCCGCCCGGTCAGCGAAGACCGCGTCTTCATCTTC
ATCGATCTCGTCGGCTCCACCTCCTTCGCCGAAACCCATGGCGATCTGAAGGCCCAGGAATTCCTCGGCGAAATCTTTGC
CAGCTATGCCGCACCAGTGAGAAGACATGGCGGCGTCATCGACGATTACATTGGCGATGCCGCCATCATCACCTGGCCCT
ATCACATGGCGATCCGGCGGGCGGCCTGCGTGCGCTGCGTGTTCGACATCCAGGCGACCATGGAGGAAAAACGCGACATG
TGGCTCTCCCGCTTCGGCGAAGTGCCACGCCTGCGTTTCGCCATCCATGGCGGGCCGGTCATCACGGCAGAAATCGGTGT
CGATCACCACAAGATCACCTATTTCGGAGATACGGTGAACACGACATCCCGGCTCGAATCGCTGAGCAAGATGCTCGGCC
ATCCGGTGCTGATTTCCGCCGATCTCGCCCACCAGCTGGTGCTTCCGAAGGGCGTACGCAGCGAATATCTCGGCGAACAT
GCGGTGAAAGGCCGTGGCCAGACGCTCGGCGTCTGCACGCTCAGCCAATATCAGGCCCCTGCCGCATAA

Upstream 100 bases:

>100_bases
ACTTTTTGCGGCGCTTTTTCCACACTAATGTCGCATATCATCTGAACAGAAGCTTTGCCCGAAGGGAGCGCCGGCTTCCC
TTTTCGAGATCAGAGCTGAC

Downstream 100 bases:

>100_bases
GGCTTATCGGCACCCGGAGGCTATTTGCCGGCGACGGCCCTCACAAAATTTCATCAAAGCTTCAAACGGCAATCACCTGC
CTGTCATGCGGCGACCCTAT

Product: adenylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 2; Adenylyl cyclase 2 [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MRKLLPILDYVVLFVAVAGAGVAYAFLEYGGGALIGATYALFACAPILAFERGYILPGLSRQVSALPTPAYIAVGLIIYA
ILVFCGFGLGGTILWLSGIFPGTWKRAVHAEVQTLIFTLIVCGIIVFIMRVRELLGRDIFIDLILGRYRRPVSEDRVFIF
IDLVGSTSFAETHGDLKAQEFLGEIFASYAAPVRRHGGVIDDYIGDAAIITWPYHMAIRRAACVRCVFDIQATMEEKRDM
WLSRFGEVPRLRFAIHGGPVITAEIGVDHHKITYFGDTVNTTSRLESLSKMLGHPVLISADLAHQLVLPKGVRSEYLGEH
AVKGRGQTLGVCTLSQYQAPAA

Sequences:

>Translated_342_residues
MRKLLPILDYVVLFVAVAGAGVAYAFLEYGGGALIGATYALFACAPILAFERGYILPGLSRQVSALPTPAYIAVGLIIYA
ILVFCGFGLGGTILWLSGIFPGTWKRAVHAEVQTLIFTLIVCGIIVFIMRVRELLGRDIFIDLILGRYRRPVSEDRVFIF
IDLVGSTSFAETHGDLKAQEFLGEIFASYAAPVRRHGGVIDDYIGDAAIITWPYHMAIRRAACVRCVFDIQATMEEKRDM
WLSRFGEVPRLRFAIHGGPVITAEIGVDHHKITYFGDTVNTTSRLESLSKMLGHPVLISADLAHQLVLPKGVRSEYLGEH
AVKGRGQTLGVCTLSQYQAPAA
>Mature_342_residues
MRKLLPILDYVVLFVAVAGAGVAYAFLEYGGGALIGATYALFACAPILAFERGYILPGLSRQVSALPTPAYIAVGLIIYA
ILVFCGFGLGGTILWLSGIFPGTWKRAVHAEVQTLIFTLIVCGIIVFIMRVRELLGRDIFIDLILGRYRRPVSEDRVFIF
IDLVGSTSFAETHGDLKAQEFLGEIFASYAAPVRRHGGVIDDYIGDAAIITWPYHMAIRRAACVRCVFDIQATMEEKRDM
WLSRFGEVPRLRFAIHGGPVITAEIGVDHHKITYFGDTVNTTSRLESLSKMLGHPVLISADLAHQLVLPKGVRSEYLGEH
AVKGRGQTLGVCTLSQYQAPAA

Specific function: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP [H]

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 37462; Mature: 37462

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLLPILDYVVLFVAVAGAGVAYAFLEYGGGALIGATYALFACAPILAFERGYILPGLS
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RQVSALPTPAYIAVGLIIYAILVFCGFGLGGTILWLSGIFPGTWKRAVHAEVQTLIFTLI
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VCGIIVFIMRVRELLGRDIFIDLILGRYRRPVSEDRVFIFIDLVGSTSFAETHGDLKAQE
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHCCCHHHHH
FLGEIFASYAAPVRRHGGVIDDYIGDAAIITWPYHMAIRRAACVRCVFDIQATMEEKRDM
HHHHHHHHHHHHHHHCCCCHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLSRFGEVPRLRFAIHGGPVITAEIGVDHHKITYFGDTVNTTSRLESLSKMLGHPVLISA
HHHHHCCCCEEEEEEECCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEH
DLAHQLVLPKGVRSEYLGEHAVKGRGQTLGVCTLSQYQAPAA
HHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEHHCCCCCCC
>Mature Secondary Structure
MRKLLPILDYVVLFVAVAGAGVAYAFLEYGGGALIGATYALFACAPILAFERGYILPGLS
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RQVSALPTPAYIAVGLIIYAILVFCGFGLGGTILWLSGIFPGTWKRAVHAEVQTLIFTLI
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VCGIIVFIMRVRELLGRDIFIDLILGRYRRPVSEDRVFIFIDLVGSTSFAETHGDLKAQE
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHCCCHHHHH
FLGEIFASYAAPVRRHGGVIDDYIGDAAIITWPYHMAIRRAACVRCVFDIQATMEEKRDM
HHHHHHHHHHHHHHHCCCCHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLSRFGEVPRLRFAIHGGPVITAEIGVDHHKITYFGDTVNTTSRLESLSKMLGHPVLISA
HHHHHCCCCEEEEEEECCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEH
DLAHQLVLPKGVRSEYLGEHAVKGRGQTLGVCTLSQYQAPAA
HHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7750735; 11481430 [H]