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The map label for this gene is 239618527

Identifier: 239618527

GI number: 239618527

Start: 2299690

End: 2300832

Strand: Direct

Name: 239618527

Synonym: Kole_2168

Alternate gene names: NA

Gene position: 2299690-2300832 (Clockwise)

Preceding gene: 239618526

Following gene: 239618528

Centisome position: 99.89

GC content: 45.76

Gene sequence:

>1143_bases
TTGTCAAAATTAGTAAAGAAAAATTATCTTCTCGCTCCCGGCCCTACACCCGTGCCAATTGATCTTTTGCTGGAAGGAGC
TCGGGACACGATTCACCACAGAACTCCCCAGTTTAAAAAGATCATGGATGAGGCAATTGAAGGAACTAAATATGTTTTCC
AGACCACAAATGATCTCTTTCTTCTTTCTTCTTCGGGGACCGGTGCCATGGAGATGGCTGTTGCAAACCTCGTTTCTCCC
GGTGAAAAGGTTATTGTTGTGGTTGGCGGTAAGTTTGGCGAACGTTGGGAAAAGATATGTAAGGTTTACGGCGCCCAGGT
AGTACCGATCAAGATTGAGTACGGTGACTATGCCACCCCTGAAATGATCGATGATGCTTTACAGGCGAATCCGGATACAG
TTGCAGTTTTCACAACCCTCAGTGAAACCTCTACCGGAACGGTAATGGACATTGAAGGGTTCAGTAAAGTTGTCAAGAAA
CACGGTAAGTTGATCGTTGTTGACGCCATCAGCGGTTTGATTGCCCAACCTCTCAAGACCGACGAATGGAACCTTGACGT
CGTTGTAGCCGGTTCTCAGAAAGGATTCATGTTGCCTCCGGGTCTTGGATTCATTACATTCAGCGAAGATGCATGGAAAA
AGGTTGAAACCACAACAACTCCACGTTTCTATTTCGATGCCCGCGCATACAAAAAGAATCCAGCTCCTTATACACCCGCT
GTCAATCTCATTTATCAGCTGAAAAAGGCTGTTGAAATGCTGAAAGAAGAAGGTATGGAAAACGTCTGGGAACGCCATAG
AATCCTTGCGGATGCCACCAGGGCAGCTATAAAAGCGCTTGGTTTGGAGTTCTTCTCCAAAAATCCAGGAAATGTTTTGA
CTGCGGTTAGAGTGCCTGAAGGCGTTGATGGCTTGAAACTCGTTTCTATCATGAGAGATGAGTACGGAGTTACTATCGCA
GGTGGTCAGGGAGACATGAAGGGTAAGATATTCAGAGTGGCTCATCTCGGTTACATGAGCAAATTCGATGTGATTATTGC
CGTCTCCGCTCTTGAAATGGTATTGAGAAAACTCGGATACAACATAGAATACGGCTCAGGTGTGAAAGCAGCAGAAGAGA
TCTTTGAGAAGGAGGGGGTTTGA

Upstream 100 bases:

>100_bases
TATTTCAGATACAGCTTCCCCATAGTCATCGTTACAGGAGTGATAGCGAGTTTGTATGTTTTATTCAGATACTATATTGC
GCTATAAGGAGGTGCTTGAA

Downstream 100 bases:

>100_bases
TGTTCAGGCTTCATGCTAATGATCCCCTGGCTCCAAAAGCAATGAATATGTTAGAGGAATCTGGACTTTTTGAAGTAACT
CAGGAGCACCTGGACAAAGA

Product: aminotransferase class V

Products: NA

Alternate protein names: Tritium exchange subunit [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSKLVKKNYLLAPGPTPVPIDLLLEGARDTIHHRTPQFKKIMDEAIEGTKYVFQTTNDLFLLSSSGTGAMEMAVANLVSP
GEKVIVVVGGKFGERWEKICKVYGAQVVPIKIEYGDYATPEMIDDALQANPDTVAVFTTLSETSTGTVMDIEGFSKVVKK
HGKLIVVDAISGLIAQPLKTDEWNLDVVVAGSQKGFMLPPGLGFITFSEDAWKKVETTTTPRFYFDARAYKKNPAPYTPA
VNLIYQLKKAVEMLKEEGMENVWERHRILADATRAAIKALGLEFFSKNPGNVLTAVRVPEGVDGLKLVSIMRDEYGVTIA
GGQGDMKGKIFRVAHLGYMSKFDVIIAVSALEMVLRKLGYNIEYGSGVKAAEEIFEKEGV

Sequences:

>Translated_380_residues
MSKLVKKNYLLAPGPTPVPIDLLLEGARDTIHHRTPQFKKIMDEAIEGTKYVFQTTNDLFLLSSSGTGAMEMAVANLVSP
GEKVIVVVGGKFGERWEKICKVYGAQVVPIKIEYGDYATPEMIDDALQANPDTVAVFTTLSETSTGTVMDIEGFSKVVKK
HGKLIVVDAISGLIAQPLKTDEWNLDVVVAGSQKGFMLPPGLGFITFSEDAWKKVETTTTPRFYFDARAYKKNPAPYTPA
VNLIYQLKKAVEMLKEEGMENVWERHRILADATRAAIKALGLEFFSKNPGNVLTAVRVPEGVDGLKLVSIMRDEYGVTIA
GGQGDMKGKIFRVAHLGYMSKFDVIIAVSALEMVLRKLGYNIEYGSGVKAAEEIFEKEGV
>Mature_379_residues
SKLVKKNYLLAPGPTPVPIDLLLEGARDTIHHRTPQFKKIMDEAIEGTKYVFQTTNDLFLLSSSGTGAMEMAVANLVSPG
EKVIVVVGGKFGERWEKICKVYGAQVVPIKIEYGDYATPEMIDDALQANPDTVAVFTTLSETSTGTVMDIEGFSKVVKKH
GKLIVVDAISGLIAQPLKTDEWNLDVVVAGSQKGFMLPPGLGFITFSEDAWKKVETTTTPRFYFDARAYKKNPAPYTPAV
NLIYQLKKAVEMLKEEGMENVWERHRILADATRAAIKALGLEFFSKNPGNVLTAVRVPEGVDGLKLVSIMRDEYGVTIAG
GQGDMKGKIFRVAHLGYMSKFDVIIAVSALEMVLRKLGYNIEYGSGVKAAEEIFEKEGV

Specific function: Soluble hydrogenase catalyzes both production and consumption of hydrogen from suitable artificial electron donors or acceptors. This subunit catalyzes the tritium-exchange activity [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=347, Percent_Identity=33.7175792507205, Blast_Score=195, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI17536281, Length=375, Percent_Identity=30.9333333333333, Blast_Score=157, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6321079, Length=365, Percent_Identity=28.7671232876712, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI17530823, Length=373, Percent_Identity=29.4906166219839, Blast_Score=155, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 41693; Mature: 41562

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLVKKNYLLAPGPTPVPIDLLLEGARDTIHHRTPQFKKIMDEAIEGTKYVFQTTNDLF
CCCCCCCCEEECCCCCCCCHHHEECCCHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCEE
LLSSSGTGAMEMAVANLVSPGEKVIVVVGGKFGERWEKICKVYGAQVVPIKIEYGDYATP
EEECCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCEEEEEEEECCCCCCH
EMIDDALQANPDTVAVFTTLSETSTGTVMDIEGFSKVVKKHGKLIVVDAISGLIAQPLKT
HHHHHHHHCCCCEEEEEEEECCCCCCCEEEHHHHHHHHHHCCCEEEEECHHHHHHCCCCC
DEWNLDVVVAGSQKGFMLPPGLGFITFSEDAWKKVETTTTPRFYFDARAYKKNPAPYTPA
CCCCEEEEEECCCCCEECCCCCEEEEECHHHHHHHCCCCCCEEEEECHHHCCCCCCCCHH
VNLIYQLKKAVEMLKEEGMENVWERHRILADATRAAIKALGLEFFSKNPGNVLTAVRVPE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
GVDGLKLVSIMRDEYGVTIAGGQGDMKGKIFRVAHLGYMSKFDVIIAVSALEMVLRKLGY
CCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEHHCCCHHHHHHHHHHHHHHHHHHHCC
NIEYGSGVKAAEEIFEKEGV
CCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SKLVKKNYLLAPGPTPVPIDLLLEGARDTIHHRTPQFKKIMDEAIEGTKYVFQTTNDLF
CCCCCCCEEECCCCCCCCHHHEECCCHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCEE
LLSSSGTGAMEMAVANLVSPGEKVIVVVGGKFGERWEKICKVYGAQVVPIKIEYGDYATP
EEECCCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCEEEEEEEECCCCCCH
EMIDDALQANPDTVAVFTTLSETSTGTVMDIEGFSKVVKKHGKLIVVDAISGLIAQPLKT
HHHHHHHHCCCCEEEEEEEECCCCCCCEEEHHHHHHHHHHCCCEEEEECHHHHHHCCCCC
DEWNLDVVVAGSQKGFMLPPGLGFITFSEDAWKKVETTTTPRFYFDARAYKKNPAPYTPA
CCCCEEEEEECCCCCEECCCCCEEEEECHHHHHHHCCCCCCEEEEECHHHCCCCCCCCHH
VNLIYQLKKAVEMLKEEGMENVWERHRILADATRAAIKALGLEFFSKNPGNVLTAVRVPE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
GVDGLKLVSIMRDEYGVTIAGGQGDMKGKIFRVAHLGYMSKFDVIIAVSALEMVLRKLGY
CCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEHHCCCHHHHHHHHHHHHHHHHHHHCC
NIEYGSGVKAAEEIFEKEGV
CCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2513553 [H]