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The map label for this gene is murQ [H]

Identifier: 239618350

GI number: 239618350

Start: 2110081

End: 2110986

Strand: Reverse

Name: murQ [H]

Synonym: Kole_1988

Alternate gene names: 239618350

Gene position: 2110986-2110081 (Counterclockwise)

Preceding gene: 239618351

Following gene: 239618349

Centisome position: 91.7

GC content: 40.07

Gene sequence:

>906_bases
ATGCTTGAAAAAGTTGAAACAGAATTACCAAACCCAAAAACCTCAAACTTCGACAATATGTCAATTGTTGAGATTTTAAG
GATCATAAATCAGGAAGATGCAACTGTTCCCCTGACGATTGCTGAGAATCTCGAAAAGATTGCCGTAGTTATTGAAATGT
GCGTTAAAGCTATTAAAAATGGTGGTCGAATAATCTATGGAGGCGCGGGAACCAGTGGCCGAATCGCTATAATAGATGCT
GTTGAAACCGTTCCCACTTTTGGTGTTCCAGAAGGATTGTTTTTACCCATTATGGCTGGTGGGGAAGAAGCCTTTCTCAG
ATCTCTCGAAGCTATTGAAGATAGTGAAAAACAAGGTGAAATTGATCTCAAAAAGCACGACGTATATTCAAAAGATCTGG
TGATTGGCTTAACTGCAAGTGGTAGAACCCCCTATGTGAAGGGAATGCTTCTTGAAGCGAAAAGAATTGGCTGTCACACC
GTGTTGATTTCTAATGTTGCCAATCCCGCACTAGAGAATATAGCAGACATCTCTGTAACCATTCGAACCGGTCCAGAAAT
AATCGCTGGAAGCACCAGAATGAAAGCTGGAACAGCACAAAAGATGGTCCTCAATATGATCAGTACAGTAACCATGATCA
AACTCGGAAAAACCTATAAAAACTATATGATTGACGTAAAAATACTCAACGAAAAGCTCAAGGCAAGAGCTGCAAGAATG
ATCTCGGAAATCACGGGAATAGATCGGGACGAGAGCCTGAAATATCTTAAATTGGCTGATAACAGTCCCAAATTGGCCGC
TCTTATGATCCTTTCTAACAAAAGCAAAGAAGAATGTATGAACGCACTTTCAAAAAGAGAAACTCTAAGTGAAGCTCTGG
AATTGTTGAGGAGTGATAAAAAATGA

Upstream 100 bases:

>100_bases
GACCGGTAAGATCAAAGCAAAAGGGAAATTACCTGTTGTGAATCGGTAAATAACCTTATACATGTAAAATATAAAAGCTT
TCGTGGAGGAGGAGCACCGA

Downstream 100 bases:

>100_bases
GGGAAGCACCTGTACCTCTTCATTATCAAATTTACCTTAAATTGAGAGAGAACATCGAAAACGGTATCTACAAAAGAGGG
GATCAACTCCCCACAGAGAA

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MLEKVETELPNPKTSNFDNMSIVEILRIINQEDATVPLTIAENLEKIAVVIEMCVKAIKNGGRIIYGGAGTSGRIAIIDA
VETVPTFGVPEGLFLPIMAGGEEAFLRSLEAIEDSEKQGEIDLKKHDVYSKDLVIGLTASGRTPYVKGMLLEAKRIGCHT
VLISNVANPALENIADISVTIRTGPEIIAGSTRMKAGTAQKMVLNMISTVTMIKLGKTYKNYMIDVKILNEKLKARAARM
ISEITGIDRDESLKYLKLADNSPKLAALMILSNKSKEECMNALSKRETLSEALELLRSDKK

Sequences:

>Translated_301_residues
MLEKVETELPNPKTSNFDNMSIVEILRIINQEDATVPLTIAENLEKIAVVIEMCVKAIKNGGRIIYGGAGTSGRIAIIDA
VETVPTFGVPEGLFLPIMAGGEEAFLRSLEAIEDSEKQGEIDLKKHDVYSKDLVIGLTASGRTPYVKGMLLEAKRIGCHT
VLISNVANPALENIADISVTIRTGPEIIAGSTRMKAGTAQKMVLNMISTVTMIKLGKTYKNYMIDVKILNEKLKARAARM
ISEITGIDRDESLKYLKLADNSPKLAALMILSNKSKEECMNALSKRETLSEALELLRSDKK
>Mature_301_residues
MLEKVETELPNPKTSNFDNMSIVEILRIINQEDATVPLTIAENLEKIAVVIEMCVKAIKNGGRIIYGGAGTSGRIAIIDA
VETVPTFGVPEGLFLPIMAGGEEAFLRSLEAIEDSEKQGEIDLKKHDVYSKDLVIGLTASGRTPYVKGMLLEAKRIGCHT
VLISNVANPALENIADISVTIRTGPEIIAGSTRMKAGTAQKMVLNMISTVTMIKLGKTYKNYMIDVKILNEKLKARAARM
ISEITGIDRDESLKYLKLADNSPKLAALMILSNKSKEECMNALSKRETLSEALELLRSDKK

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate [H]

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=285, Percent_Identity=42.8070175438597, Blast_Score=225, Evalue=4e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 32894; Mature: 32894

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKVETELPNPKTSNFDNMSIVEILRIINQEDATVPLTIAENLEKIAVVIEMCVKAIKN
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHC
GGRIIYGGAGTSGRIAIIDAVETVPTFGVPEGLFLPIMAGGEEAFLRSLEAIEDSEKQGE
CCEEEECCCCCCCCEEEEECHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCC
IDLKKHDVYSKDLVIGLTASGRTPYVKGMLLEAKRIGCHTVLISNVANPALENIADISVT
CEEHHCCCCCCCEEEEEECCCCCCHHHHEEHHHHHCCHHHHHHHHHCCHHHHHHHEEEEE
IRTGPEIIAGSTRMKAGTAQKMVLNMISTVTMIKLGKTYKNYMIDVKILNEKLKARAARM
EECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHEEEEEHHHHHHHHHHHHH
ISEITGIDRDESLKYLKLADNSPKLAALMILSNKSKEECMNALSKRETLSEALELLRSDK
HHHHHCCCCCCCCEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
K
C
>Mature Secondary Structure
MLEKVETELPNPKTSNFDNMSIVEILRIINQEDATVPLTIAENLEKIAVVIEMCVKAIKN
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHC
GGRIIYGGAGTSGRIAIIDAVETVPTFGVPEGLFLPIMAGGEEAFLRSLEAIEDSEKQGE
CCEEEECCCCCCCCEEEEECHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCC
IDLKKHDVYSKDLVIGLTASGRTPYVKGMLLEAKRIGCHTVLISNVANPALENIADISVT
CEEHHCCCCCCCEEEEEECCCCCCHHHHEEHHHHHCCHHHHHHHHHCCHHHHHHHEEEEE
IRTGPEIIAGSTRMKAGTAQKMVLNMISTVTMIKLGKTYKNYMIDVKILNEKLKARAARM
EECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHEEEEEHHHHHHHHHHHHH
ISEITGIDRDESLKYLKLADNSPKLAALMILSNKSKEECMNALSKRETLSEALELLRSDK
HHHHHCCCCCCCCEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA