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The map label for this gene is fusA [C]

Identifier: 239617947

GI number: 239617947

Start: 1688964

End: 1691027

Strand: Direct

Name: fusA [C]

Synonym: Kole_1575

Alternate gene names: 239617947

Gene position: 1688964-1691027 (Clockwise)

Preceding gene: 239617946

Following gene: 239617948

Centisome position: 73.37

GC content: 44.86

Gene sequence:

>2064_bases
ATGGGGAAAGTACCAGTTGAAGCCAAAAGAAACGTAACCTTGATAGGACATCATGGTTCAGGAAAAACACATCTCGTTGA
CTCTTTGCTTTTTAACGTGGGAATGATCGACAGAACGGGAATCTTCGTTACCGATAACGAAGAGATTGAAAAAGAGAGAA
AGGCGACGTTCTCCCTTGGCGTAACAGGGCTCGAGTACAAAAATACCAGAATAAACATCGTTGATACACCCGGTATGCCG
GATTTTCATGCCGAAACTGTGAACGGTATCTATGCTTCTGAGAATATTCTGCTGGTTCTAAATGCTACAGCAGGGATGGA
GATTCAATCGGAAAGATTCGGGGCTGTTGCCAAAGAGCTCAGCAAGGGAATAATAGTCTTTTTCAATATGATGGATAAAG
ACAGAGCGGAATACGAAGCAGCTCTTTCTGACATCAAAGAAACCTTCGAGAGAAGTCCGGTACTTCTGCAGTTGCCCATA
GGGACAGCCGCGGAGTTCAAAGGCGTAATTGATCTGATCGAAGGAAAGGCTTACATTTACGATAATGGCAAACCGCAGGT
TCAGGAGCTTCCTGATGATCTAAAAGATCAATATGAAGAAGCGAGAACCAGGATGATTGAGGACATTGTAGAAACCGATG
AAGAACTAATGGAAAAGTATTTTGAAGGCGAAGAAATCACAACGGAAGAGATTAAAAGGGCCTTAAAAACAGCCTATATA
AACAATCAGATTATTCCCGTTCTTTTTGGATCGGCTCTAAAGAACATAGGAACAGATAGGCTCTTAGAGACCATCGTTGA
TCTTGGCAAGAATCCTGCTGAAGGTGGGAAATGGCCCGCGCAGCTTCAGAGCGGTGAGGAGATTGAAATATCCCCGGTTG
AAAACGAACCCTTTGCCGGGTACATCTTCAAATCTGTTGTTGATCCGTTTGTTGGTAAGTTGACCTTTATCAAGATTATC
TCGGGAATCCTTAAACCGGGAGATAGCATAGTCGTGGTTGACGAAGAATCCACGGAAAAGGTGAGTCATATTCTGGCACC
AAATGGTACCAAGGATATTGAACTAGAGGAAGCCTCTGTTGGCGATATCATAAAGCTAGCTAAGCTCAAAAAATCAGCTG
TTGGAGACACCGTAACTCATAAAGACAGGCAACTTAAGGTCAAGCTTCTCAACTGGCCAGAACCGATGATTTCCAAGTCA
ATACACCCGAAATCGAAAACAGACATCGACAAGATAAGCAACGGATTGTCCAGGCTTTCCGAATCCGATCCCACCTTCAA
CTGGGAATACGATCCTGAGACCGGTGAAACGGTCATTTCCGGGCTGGGGTCATTGCATCTCGATATTATGATCGACAGGC
TCAAGAGACTTTTCTCTGTGGATGTCGAAGTTGGAAAACCAAAGATAGCTTACAGAGAAACCATCAGGAAAAAGGTTGTT
GCCGAGTACAAGCACAAGAAACAGACCGGCGGTCATGGACAGTATGGACACGTTCAGATAGAGATAGAACCCCTTGAAAG
GGGAGCGGGCTTCGAGTTCGTTGATAAGATAGTCGGTGGCGTTATACCAAAGAACTACATCCCTGCGGTTGAAAAGGGCG
TTAAAGAAGCCATGAAAAAGGGTGTCCTCGCTGGTTATCCTGTAGTTGACGTTAAGGTCACCCTGGTATATGGTTCTTAC
CACGAAGTCGATTCTTCCGATATGTCATTCCAGATTGCTGCAAGTCAGGCCTTCAAAAAAGGAATGGCTGAAGCCAACCC
TGTTATTCTTGAACCGATAATGGATGTTGAAATCTTCGTTCCGGATGATAATGCTGGAGACGTGATGGGTGAAGTCACAT
CCAGAAGAGGCCGCCCCATGGGGATGGAAACATTGGGGAAAGGTACCACGAAGGTTCTTGCGCAGGTGCCTCTTGCAGAA
ATGCTTGATTTTGCCAACAAGTTGAACTCCATAACCAGCGGTAGAGGTTATTTCACAATGAAATTTGCCGGTTACCAGGA
GACGCCTTCAGATGTTCAGCAAAAAGTGATTGTTGAACGCGAAAGAGAGCAAGAAAACGGTTAA

Upstream 100 bases:

>100_bases
GTTTTCAAAGGAGAGGTTTTCAGCTCTCCTTCTTCGGGTGTTCCCGTCGTTCCTGTGGGAATAGTTATAAGTCAAAAATA
GAGTTCTGGAGGTGGAAGAA

Downstream 100 bases:

>100_bases
TAAGCACAAAGAAGACGATTTTGGGGGGCGATAGAGCCCCCTTTTTTGGGAGGTAAAATGGCAAAGGATACGCAGGTTAC
GGCCTTTGACTTAGCGATTT

Product: translation elongation factor G

Products: GDP; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 687; Mature: 686

Protein sequence:

>687_residues
MGKVPVEAKRNVTLIGHHGSGKTHLVDSLLFNVGMIDRTGIFVTDNEEIEKERKATFSLGVTGLEYKNTRINIVDTPGMP
DFHAETVNGIYASENILLVLNATAGMEIQSERFGAVAKELSKGIIVFFNMMDKDRAEYEAALSDIKETFERSPVLLQLPI
GTAAEFKGVIDLIEGKAYIYDNGKPQVQELPDDLKDQYEEARTRMIEDIVETDEELMEKYFEGEEITTEEIKRALKTAYI
NNQIIPVLFGSALKNIGTDRLLETIVDLGKNPAEGGKWPAQLQSGEEIEISPVENEPFAGYIFKSVVDPFVGKLTFIKII
SGILKPGDSIVVVDEESTEKVSHILAPNGTKDIELEEASVGDIIKLAKLKKSAVGDTVTHKDRQLKVKLLNWPEPMISKS
IHPKSKTDIDKISNGLSRLSESDPTFNWEYDPETGETVISGLGSLHLDIMIDRLKRLFSVDVEVGKPKIAYRETIRKKVV
AEYKHKKQTGGHGQYGHVQIEIEPLERGAGFEFVDKIVGGVIPKNYIPAVEKGVKEAMKKGVLAGYPVVDVKVTLVYGSY
HEVDSSDMSFQIAASQAFKKGMAEANPVILEPIMDVEIFVPDDNAGDVMGEVTSRRGRPMGMETLGKGTTKVLAQVPLAE
MLDFANKLNSITSGRGYFTMKFAGYQETPSDVQQKVIVEREREQENG

Sequences:

>Translated_687_residues
MGKVPVEAKRNVTLIGHHGSGKTHLVDSLLFNVGMIDRTGIFVTDNEEIEKERKATFSLGVTGLEYKNTRINIVDTPGMP
DFHAETVNGIYASENILLVLNATAGMEIQSERFGAVAKELSKGIIVFFNMMDKDRAEYEAALSDIKETFERSPVLLQLPI
GTAAEFKGVIDLIEGKAYIYDNGKPQVQELPDDLKDQYEEARTRMIEDIVETDEELMEKYFEGEEITTEEIKRALKTAYI
NNQIIPVLFGSALKNIGTDRLLETIVDLGKNPAEGGKWPAQLQSGEEIEISPVENEPFAGYIFKSVVDPFVGKLTFIKII
SGILKPGDSIVVVDEESTEKVSHILAPNGTKDIELEEASVGDIIKLAKLKKSAVGDTVTHKDRQLKVKLLNWPEPMISKS
IHPKSKTDIDKISNGLSRLSESDPTFNWEYDPETGETVISGLGSLHLDIMIDRLKRLFSVDVEVGKPKIAYRETIRKKVV
AEYKHKKQTGGHGQYGHVQIEIEPLERGAGFEFVDKIVGGVIPKNYIPAVEKGVKEAMKKGVLAGYPVVDVKVTLVYGSY
HEVDSSDMSFQIAASQAFKKGMAEANPVILEPIMDVEIFVPDDNAGDVMGEVTSRRGRPMGMETLGKGTTKVLAQVPLAE
MLDFANKLNSITSGRGYFTMKFAGYQETPSDVQQKVIVEREREQENG
>Mature_686_residues
GKVPVEAKRNVTLIGHHGSGKTHLVDSLLFNVGMIDRTGIFVTDNEEIEKERKATFSLGVTGLEYKNTRINIVDTPGMPD
FHAETVNGIYASENILLVLNATAGMEIQSERFGAVAKELSKGIIVFFNMMDKDRAEYEAALSDIKETFERSPVLLQLPIG
TAAEFKGVIDLIEGKAYIYDNGKPQVQELPDDLKDQYEEARTRMIEDIVETDEELMEKYFEGEEITTEEIKRALKTAYIN
NQIIPVLFGSALKNIGTDRLLETIVDLGKNPAEGGKWPAQLQSGEEIEISPVENEPFAGYIFKSVVDPFVGKLTFIKIIS
GILKPGDSIVVVDEESTEKVSHILAPNGTKDIELEEASVGDIIKLAKLKKSAVGDTVTHKDRQLKVKLLNWPEPMISKSI
HPKSKTDIDKISNGLSRLSESDPTFNWEYDPETGETVISGLGSLHLDIMIDRLKRLFSVDVEVGKPKIAYRETIRKKVVA
EYKHKKQTGGHGQYGHVQIEIEPLERGAGFEFVDKIVGGVIPKNYIPAVEKGVKEAMKKGVLAGYPVVDVKVTLVYGSYH
EVDSSDMSFQIAASQAFKKGMAEANPVILEPIMDVEIFVPDDNAGDVMGEVTSRRGRPMGMETLGKGTTKVLAQVPLAEM
LDFANKLNSITSGRGYFTMKFAGYQETPSDVQQKVIVEREREQENG

Specific function: This Protein Promotes The GTP-Dependent Translocation Of The Nascent Protein Chain From The A-Site To The P-Site Of The Ribosome. [C]

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=697, Percent_Identity=34.1463414634146, Blast_Score=385, Evalue=1e-107,
Organism=Homo sapiens, GI19923640, Length=725, Percent_Identity=28, Blast_Score=289, Evalue=6e-78,
Organism=Homo sapiens, GI25306287, Length=713, Percent_Identity=26.2272089761571, Blast_Score=226, Evalue=6e-59,
Organism=Homo sapiens, GI25306283, Length=393, Percent_Identity=27.9898218829517, Blast_Score=159, Evalue=8e-39,
Organism=Homo sapiens, GI157426893, Length=156, Percent_Identity=32.0512820512821, Blast_Score=77, Evalue=7e-14,
Organism=Escherichia coli, GI1789738, Length=698, Percent_Identity=40.8309455587393, Blast_Score=513, Evalue=1e-146,
Organism=Escherichia coli, GI1790835, Length=507, Percent_Identity=23.8658777120316, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI48994988, Length=175, Percent_Identity=33.1428571428571, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788922, Length=190, Percent_Identity=26.8421052631579, Blast_Score=63, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17533571, Length=700, Percent_Identity=31.4285714285714, Blast_Score=356, Evalue=2e-98,
Organism=Caenorhabditis elegans, GI17556745, Length=714, Percent_Identity=22.5490196078431, Blast_Score=182, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17557151, Length=144, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6323098, Length=696, Percent_Identity=32.7586206896552, Blast_Score=362, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6322359, Length=802, Percent_Identity=24.8129675810474, Blast_Score=223, Evalue=9e-59,
Organism=Saccharomyces cerevisiae, GI6324707, Length=807, Percent_Identity=21.6852540272615, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6320593, Length=807, Percent_Identity=21.6852540272615, Blast_Score=100, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24582462, Length=701, Percent_Identity=34.0941512125535, Blast_Score=397, Evalue=1e-110,
Organism=Drosophila melanogaster, GI221458488, Length=710, Percent_Identity=26.7605633802817, Blast_Score=241, Evalue=1e-63,
Organism=Drosophila melanogaster, GI78706572, Length=159, Percent_Identity=28.9308176100629, Blast_Score=74, Evalue=4e-13,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 76033; Mature: 75902

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKVPVEAKRNVTLIGHHGSGKTHLVDSLLFNVGMIDRTGIFVTDNEEIEKERKATFSLG
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEECCCEEEECCHHHHHHHHHHHEEC
VTGLEYKNTRINIVDTPGMPDFHAETVNGIYASENILLVLNATAGMEIQSERFGAVAKEL
CCCEEECCCEEEEEECCCCCCCCHHHHCCEEECCCEEEEEECCCCCEECHHHHHHHHHHH
SKGIIVFFNMMDKDRAEYEAALSDIKETFERSPVLLQLPIGTAAEFKGVIDLIEGKAYIY
CCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCEEEE
DNGKPQVQELPDDLKDQYEEARTRMIEDIVETDEELMEKYFEGEEITTEEIKRALKTAYI
ECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
NNQIIPVLFGSALKNIGTDRLLETIVDLGKNPAEGGKWPAQLQSGEEIEISPVENEPFAG
CCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCHHCCCCCEEEEECCCCCCCHH
YIFKSVVDPFVGKLTFIKIISGILKPGDSIVVVDEESTEKVSHILAPNGTKDIELEEASV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCCCCEECCCCH
GDIIKLAKLKKSAVGDTVTHKDRQLKVKLLNWPEPMISKSIHPKSKTDIDKISNGLSRLS
HHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHHHH
ESDPTFNWEYDPETGETVISGLGSLHLDIMIDRLKRLFSVDVEVGKPKIAYRETIRKKVV
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
AEYKHKKQTGGHGQYGHVQIEIEPLERGAGFEFVDKIVGGVIPKNYIPAVEKGVKEAMKK
HHHHHHHCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHC
GVLAGYPVVDVKVTLVYGSYHEVDSSDMSFQIAASQAFKKGMAEANPVILEPIMDVEIFV
CCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEHHHHHHHHCCCCCCCEEEEECCCEEEEE
PDDNAGDVMGEVTSRRGRPMGMETLGKGTTKVLAQVPLAEMLDFANKLNSITSGRGYFTM
CCCCCCHHHHHHHHCCCCCCCHHHHCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEE
KFAGYQETPSDVQQKVIVEREREQENG
EECCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GKVPVEAKRNVTLIGHHGSGKTHLVDSLLFNVGMIDRTGIFVTDNEEIEKERKATFSLG
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEECCCEEEECCHHHHHHHHHHHEEC
VTGLEYKNTRINIVDTPGMPDFHAETVNGIYASENILLVLNATAGMEIQSERFGAVAKEL
CCCEEECCCEEEEEECCCCCCCCHHHHCCEEECCCEEEEEECCCCCEECHHHHHHHHHHH
SKGIIVFFNMMDKDRAEYEAALSDIKETFERSPVLLQLPIGTAAEFKGVIDLIEGKAYIY
CCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCEEEE
DNGKPQVQELPDDLKDQYEEARTRMIEDIVETDEELMEKYFEGEEITTEEIKRALKTAYI
ECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
NNQIIPVLFGSALKNIGTDRLLETIVDLGKNPAEGGKWPAQLQSGEEIEISPVENEPFAG
CCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCHHCCCCCEEEEECCCCCCCHH
YIFKSVVDPFVGKLTFIKIISGILKPGDSIVVVDEESTEKVSHILAPNGTKDIELEEASV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCCCCEECCCCH
GDIIKLAKLKKSAVGDTVTHKDRQLKVKLLNWPEPMISKSIHPKSKTDIDKISNGLSRLS
HHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHHHH
ESDPTFNWEYDPETGETVISGLGSLHLDIMIDRLKRLFSVDVEVGKPKIAYRETIRKKVV
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
AEYKHKKQTGGHGQYGHVQIEIEPLERGAGFEFVDKIVGGVIPKNYIPAVEKGVKEAMKK
HHHHHHHCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHC
GVLAGYPVVDVKVTLVYGSYHEVDSSDMSFQIAASQAFKKGMAEANPVILEPIMDVEIFV
CCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEHHHHHHHHCCCCCCCEEEEECCCEEEEE
PDDNAGDVMGEVTSRRGRPMGMETLGKGTTKVLAQVPLAEMLDFANKLNSITSGRGYFTM
CCCCCCHHHHHHHHCCCCCCCHHHHCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEE
KFAGYQETPSDVQQKVIVEREREQENG
EECCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]