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The map label for this gene is pdp [H]

Identifier: 239617945

GI number: 239617945

Start: 1685950

End: 1687251

Strand: Direct

Name: pdp [H]

Synonym: Kole_1573

Alternate gene names: 239617945

Gene position: 1685950-1687251 (Clockwise)

Preceding gene: 239617944

Following gene: 239617946

Centisome position: 73.23

GC content: 44.09

Gene sequence:

>1302_bases
ATGAGAGCTTATGATGTTATTTTGAAGAAGAGAAATGGATTACCAAATTCACATGAGGAATTGAAGTTTCTTATTGAAGG
TTATGTTAAAGGGGAAGTGCCGGATTATCAGGTATCAGCGTGGTTGATGGCTGTGTATTTCAACCATTTGACTCCAGAAG
AGCGCTTTGATATGACAAGGATAATGCTGGAATCCGGCGATCAAATCAGTTTAAGTGAAGTCAACGGAATAAAGGTTGAC
AAACATTCCACAGGTGGTGTTGGGGATAAAGTCACCCTTGTTGTCGGTCCCATTGTAGCTGCAGCTGGTTTAACCATGGC
CAAGCTTTCCGGAAGAGGATTGGGTCACACCGGCGGAACCATAGACAAGCTGGAATCTATACCCGGGTTCAGAACAGCTT
TAAAGAAGGAAGAATTCTTCAAGATAGCAAACGAGGTTGGATTGGTTGTAGCGGGTCAGACAGCGACAGTGGCACCGGCT
GACAAAAAGCTTTACGCTTTGAGGGATGTCACAGCTACGGTTGATGAGATATCTCTTATAGCTTCCAGTATAATGAGCAA
GAAATTAGCCATTCACTCTGATGTGATAGTGCTGGATGTTAAGGTTGGAACCGGTGCATTCATGAAGTCCATTGAGGAAG
CAACGGAGCTGGCCAGGGCGATGATAGATATTGGAAAGAGGTATGGAAGAAAAATAGGTGCTGTTGTCAGTGATATGAAT
CAGCCTCTTGGAAAGATGGTTGGTAATGCTTTGGAGGTCAAAGAAGCCGTAGAGACCTTGAAAGGGAATGGGCCCGAAGA
TTTAGATAGGTTGTGCAGGCTCATTTCCGCAAGACTGATAGAACTCGCCAGAGGAGTTTCTTCAGAGGAAGCAGAGAAGA
TGGTAAAAGATGTTCTGGAATCTGGAGAAGCTCTGGAGAAATTCAGAAGCTTTGTCATTGCTCAAGGCGGGGATGGATCA
GTCGTTGACTCGCCAGAATCGGTGCTTCCTGCAGCGAAGGGAACGATGGAAGTTTTAAGTTCAAAAGATGGTTATATTTC
TTATATAGACGCCGAGCAGGTGGGAATTTCCTCGATGATTCTCGGTGCTGGTCGTGCGAAAAAAGAAGATGCAATCGACT
ATGCTGTGGGAATAGAGGTTTTCAAGAAGCTTGGAGATAGGGTACTTAAGGGTGATCCCATTGCTCGTCTGTATTTCAAT
GATGAAGAGAAAGCAGAGAAAGCAAAGGAACTATTTTTAGAAGCGTACAAGATTTCTGATGCTCCAATTGAACCACCATC
TCTGGTACATGAGATTTTTTAA

Upstream 100 bases:

>100_bases
AATTGATCGCTGAAAAACACGGTGGAACGGTTTCACTGGACAGTGAATTTGGAAATGGGACAACGTTTAAAGTTAGATTA
CCACTTAAGAAGGTGATAGA

Downstream 100 bases:

>100_bases
GGGGTTTGTGTAAGATATGCGCAGATCAGTTATAATAATTCTTCTCGTTTTTTGTGCGGTCATCTCGATTGGTAAGGATG
TTGTTTTTTCTCTCGAGAAT

Product: pyrimidine-nucleoside phosphorylase

Products: NA

Alternate protein names: PYNP [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MRAYDVILKKRNGLPNSHEELKFLIEGYVKGEVPDYQVSAWLMAVYFNHLTPEERFDMTRIMLESGDQISLSEVNGIKVD
KHSTGGVGDKVTLVVGPIVAAAGLTMAKLSGRGLGHTGGTIDKLESIPGFRTALKKEEFFKIANEVGLVVAGQTATVAPA
DKKLYALRDVTATVDEISLIASSIMSKKLAIHSDVIVLDVKVGTGAFMKSIEEATELARAMIDIGKRYGRKIGAVVSDMN
QPLGKMVGNALEVKEAVETLKGNGPEDLDRLCRLISARLIELARGVSSEEAEKMVKDVLESGEALEKFRSFVIAQGGDGS
VVDSPESVLPAAKGTMEVLSSKDGYISYIDAEQVGISSMILGAGRAKKEDAIDYAVGIEVFKKLGDRVLKGDPIARLYFN
DEEKAEKAKELFLEAYKISDAPIEPPSLVHEIF

Sequences:

>Translated_433_residues
MRAYDVILKKRNGLPNSHEELKFLIEGYVKGEVPDYQVSAWLMAVYFNHLTPEERFDMTRIMLESGDQISLSEVNGIKVD
KHSTGGVGDKVTLVVGPIVAAAGLTMAKLSGRGLGHTGGTIDKLESIPGFRTALKKEEFFKIANEVGLVVAGQTATVAPA
DKKLYALRDVTATVDEISLIASSIMSKKLAIHSDVIVLDVKVGTGAFMKSIEEATELARAMIDIGKRYGRKIGAVVSDMN
QPLGKMVGNALEVKEAVETLKGNGPEDLDRLCRLISARLIELARGVSSEEAEKMVKDVLESGEALEKFRSFVIAQGGDGS
VVDSPESVLPAAKGTMEVLSSKDGYISYIDAEQVGISSMILGAGRAKKEDAIDYAVGIEVFKKLGDRVLKGDPIARLYFN
DEEKAEKAKELFLEAYKISDAPIEPPSLVHEIF
>Mature_433_residues
MRAYDVILKKRNGLPNSHEELKFLIEGYVKGEVPDYQVSAWLMAVYFNHLTPEERFDMTRIMLESGDQISLSEVNGIKVD
KHSTGGVGDKVTLVVGPIVAAAGLTMAKLSGRGLGHTGGTIDKLESIPGFRTALKKEEFFKIANEVGLVVAGQTATVAPA
DKKLYALRDVTATVDEISLIASSIMSKKLAIHSDVIVLDVKVGTGAFMKSIEEATELARAMIDIGKRYGRKIGAVVSDMN
QPLGKMVGNALEVKEAVETLKGNGPEDLDRLCRLISARLIELARGVSSEEAEKMVKDVLESGEALEKFRSFVIAQGGDGS
VVDSPESVLPAAKGTMEVLSSKDGYISYIDAEQVGISSMILGAGRAKKEDAIDYAVGIEVFKKLGDRVLKGDPIARLYFN
DEEKAEKAKELFLEAYKISDAPIEPPSLVHEIF

Specific function: The Enzymes Which Catalyze The Reversible Phosphorolysis Of Pyrimidine Nucleosides Are Involved In The Degradation Of These Compounds And In Their Utilization As Carbon And Energy Sources, Or In The Rescue Of Pyrimidine Bases For Nucleotide Synthesis. [C

COG id: COG0213

COG function: function code F; Thymidine phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI166158925, Length=439, Percent_Identity=36.4464692482916, Blast_Score=262, Evalue=5e-70,
Organism=Homo sapiens, GI4503445, Length=439, Percent_Identity=36.4464692482916, Blast_Score=262, Evalue=5e-70,
Organism=Homo sapiens, GI166158922, Length=439, Percent_Identity=36.4464692482916, Blast_Score=262, Evalue=5e-70,
Organism=Escherichia coli, GI1790842, Length=436, Percent_Identity=41.2844036697248, Blast_Score=302, Evalue=3e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR013102
- InterPro:   IPR018090
- InterPro:   IPR000053
- InterPro:   IPR017872 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; PF07831 PYNP_C [H]

EC number: =2.4.2.2 [H]

Molecular weight: Translated: 46823; Mature: 46823

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00647 THYMID_PHOSPHORYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAYDVILKKRNGLPNSHEELKFLIEGYVKGEVPDYQVSAWLMAVYFNHLTPEERFDMTR
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
IMLESGDQISLSEVNGIKVDKHSTGGVGDKVTLVVGPIVAAAGLTMAKLSGRGLGHTGGT
HHHHCCCEEEEECCCCEEEECCCCCCCCCEEEEEEHHHHHHHCHHHHHHCCCCCCCCCCC
IDKLESIPGFRTALKKEEFFKIANEVGLVVAGQTATVAPADKKLYALRDVTATVDEISLI
HHHHHCCCCHHHHHHHHHHHHHHHHCCEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHH
ASSIMSKKLAIHSDVIVLDVKVGTGAFMKSIEEATELARAMIDIGKRYGRKIGAVVSDMN
HHHHHHHHHHEECCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QPLGKMVGNALEVKEAVETLKGNGPEDLDRLCRLISARLIELARGVSSEEAEKMVKDVLE
HHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SGEALEKFRSFVIAQGGDGSVVDSPESVLPAAKGTMEVLSSKDGYISYIDAEQVGISSMI
CCHHHHHHHHHEEECCCCCCCCCCCHHHCCCCHHHHHHHCCCCCEEEEECHHHHCHHHHH
LGAGRAKKEDAIDYAVGIEVFKKLGDRVLKGDPIARLYFNDEEKAEKAKELFLEAYKISD
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHCCC
APIEPPSLVHEIF
CCCCCHHHHHHCC
>Mature Secondary Structure
MRAYDVILKKRNGLPNSHEELKFLIEGYVKGEVPDYQVSAWLMAVYFNHLTPEERFDMTR
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
IMLESGDQISLSEVNGIKVDKHSTGGVGDKVTLVVGPIVAAAGLTMAKLSGRGLGHTGGT
HHHHCCCEEEEECCCCEEEECCCCCCCCCEEEEEEHHHHHHHCHHHHHHCCCCCCCCCCC
IDKLESIPGFRTALKKEEFFKIANEVGLVVAGQTATVAPADKKLYALRDVTATVDEISLI
HHHHHCCCCHHHHHHHHHHHHHHHHCCEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHH
ASSIMSKKLAIHSDVIVLDVKVGTGAFMKSIEEATELARAMIDIGKRYGRKIGAVVSDMN
HHHHHHHHHHEECCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QPLGKMVGNALEVKEAVETLKGNGPEDLDRLCRLISARLIELARGVSSEEAEKMVKDVLE
HHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SGEALEKFRSFVIAQGGDGSVVDSPESVLPAAKGTMEVLSSKDGYISYIDAEQVGISSMI
CCHHHHHHHHHEEECCCCCCCCCCCHHHCCCCHHHHHHHCCCCCEEEEECHHHHCHHHHH
LGAGRAKKEDAIDYAVGIEVFKKLGDRVLKGDPIARLYFNDEEKAEKAKELFLEAYKISD
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHCCC
APIEPPSLVHEIF
CCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8987664; 9817849 [H]