Click here to switch to the map view.

The map label for this gene is yybE [H]

Identifier: 238925191

GI number: 238925191

Start: 2727048

End: 2727929

Strand: Reverse

Name: yybE [H]

Synonym: EUBREC_2845

Alternate gene names: 238925191

Gene position: 2727929-2727048 (Counterclockwise)

Preceding gene: 238925194

Following gene: 238925189

Centisome position: 79.08

GC content: 45.58

Gene sequence:

>882_bases
ATGAATCTGAGTCAATTGCAGTACTTCAAGGTACTGGCGCAGGAAGAACATTATACGAGGGCGGCACAGATGCTGTCGAT
TACGCAGCCGTCTTTAAGCCATGCAATCTCACAGCTGGAGCAGGAGCTTGGCACGCGTTTGTTTGAGAAAAAGGGAAGAA
ATGTCGTGCTGACCAGATATGGGAAGATGTTTCTGCCGTATGTTGAGGAATCATTAAAGGTGCTTAATGAGGGTGTGCAG
CGCATTCAGGAGGTCAATGGCAGCAGGCATGGAATTATACATCTGGCATATATATATACGATGGGAAGTGAGTTCGCGCC
AAAGCTGGTGCGTAAATTTCTCGATGCATACCCGGATTATGATATAGAATTTCATTTTACGGTTGGAACAACCGGAGAGA
TTATAGATGGACTAAAGGATGACAAATATGACATAGTTTTCTCTTCTTATAAGGATGGGGAACAGGATATAGATTTTAAG
AAGATCGCGAATCAGAAGCTTGTGCTTGCAGTGCCCATGGACCATCCGCTTTCCATAAAGGACAGTGTGGATTTGCGCGA
TACAATAGAGTATCCGCAGATTTATTTTGAGAAGGGCAGCGGTCTGCGTCCGGTCATTGATCAGATGTTTGAGGAGATAG
GACAGTTTCCGAAGGTAGCCTTCGAGATGGAGGAGGATTCGAGTATGGCGGGTCTCGTGGCGCAGGGCTTTGGAATAGCT
GTGATGCCTGATATTCCAATACTTCGGTCACTTTCTGTAAAGACGCTTGATATATACAATCCTCCTTATGAGAGAGCGGT
GTATCTGGCAACGCTTAAGCAGAGATATTTATCACCGGTTGCGAAGGCATTTATCAGGTTTGTGATCGAGGAGACTGCCT
AG

Upstream 100 bases:

>100_bases
CCACACGACACGTCATAAATCGAGCATATACCACCGGTGTGCAGCGCAGGGCAAGCGGACCTCCGGCGAATAAATATATT
AAATACATAGGGGGTGTACT

Downstream 100 bases:

>100_bases
CTGCAGCTTTCCCGCACAAACTCTATGAAGCGCTTGATAGCCGGAAGCTGGTATTTGCCTGTCATGTAGCCCATGTATAC
AGTGTGTGAGAATGACTCAT

Product: transcription activator of glutamate synthase(LysR family)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MNLSQLQYFKVLAQEEHYTRAAQMLSITQPSLSHAISQLEQELGTRLFEKKGRNVVLTRYGKMFLPYVEESLKVLNEGVQ
RIQEVNGSRHGIIHLAYIYTMGSEFAPKLVRKFLDAYPDYDIEFHFTVGTTGEIIDGLKDDKYDIVFSSYKDGEQDIDFK
KIANQKLVLAVPMDHPLSIKDSVDLRDTIEYPQIYFEKGSGLRPVIDQMFEEIGQFPKVAFEMEEDSSMAGLVAQGFGIA
VMPDIPILRSLSVKTLDIYNPPYERAVYLATLKQRYLSPVAKAFIRFVIEETA

Sequences:

>Translated_293_residues
MNLSQLQYFKVLAQEEHYTRAAQMLSITQPSLSHAISQLEQELGTRLFEKKGRNVVLTRYGKMFLPYVEESLKVLNEGVQ
RIQEVNGSRHGIIHLAYIYTMGSEFAPKLVRKFLDAYPDYDIEFHFTVGTTGEIIDGLKDDKYDIVFSSYKDGEQDIDFK
KIANQKLVLAVPMDHPLSIKDSVDLRDTIEYPQIYFEKGSGLRPVIDQMFEEIGQFPKVAFEMEEDSSMAGLVAQGFGIA
VMPDIPILRSLSVKTLDIYNPPYERAVYLATLKQRYLSPVAKAFIRFVIEETA
>Mature_293_residues
MNLSQLQYFKVLAQEEHYTRAAQMLSITQPSLSHAISQLEQELGTRLFEKKGRNVVLTRYGKMFLPYVEESLKVLNEGVQ
RIQEVNGSRHGIIHLAYIYTMGSEFAPKLVRKFLDAYPDYDIEFHFTVGTTGEIIDGLKDDKYDIVFSSYKDGEQDIDFK
KIANQKLVLAVPMDHPLSIKDSVDLRDTIEYPQIYFEKGSGLRPVIDQMFEEIGQFPKVAFEMEEDSSMAGLVAQGFGIA
VMPDIPILRSLSVKTLDIYNPPYERAVYLATLKQRYLSPVAKAFIRFVIEETA

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=290, Percent_Identity=29.3103448275862, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI157672245, Length=289, Percent_Identity=26.2975778546713, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787879, Length=250, Percent_Identity=28, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788481, Length=293, Percent_Identity=24.9146757679181, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790399, Length=252, Percent_Identity=26.5873015873016, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1788748, Length=296, Percent_Identity=25.6756756756757, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI2367136, Length=253, Percent_Identity=28.4584980237154, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788296, Length=249, Percent_Identity=26.9076305220884, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788887, Length=249, Percent_Identity=25.3012048192771, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI87081904, Length=227, Percent_Identity=25.5506607929515, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787806, Length=245, Percent_Identity=25.7142857142857, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787530, Length=250, Percent_Identity=22, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787601, Length=250, Percent_Identity=22.4, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789204, Length=242, Percent_Identity=22.3140495867769, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790208, Length=298, Percent_Identity=22.8187919463087, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082132, Length=303, Percent_Identity=26.0726072607261, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788297, Length=245, Percent_Identity=23.265306122449, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787589, Length=129, Percent_Identity=27.906976744186, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33472; Mature: 33472

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSQLQYFKVLAQEEHYTRAAQMLSITQPSLSHAISQLEQELGTRLFEKKGRNVVLTRY
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHH
GKMFLPYVEESLKVLNEGVQRIQEVNGSRHGIIHLAYIYTMGSEFAPKLVRKFLDAYPDY
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHCCHHHHHHHHHHHHHCCCC
DIEFHFTVGTTGEIIDGLKDDKYDIVFSSYKDGEQDIDFKKIANQKLVLAVPMDHPLSIK
CEEEEEEECCCHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHCCCEEEEEECCCCCCCCC
DSVDLRDTIEYPQIYFEKGSGLRPVIDQMFEEIGQFPKVAFEMEEDSSMAGLVAQGFGIA
CCCCHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHCCCCEE
VMPDIPILRSLSVKTLDIYNPPYERAVYLATLKQRYLSPVAKAFIRFVIEETA
ECCCCCHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLSQLQYFKVLAQEEHYTRAAQMLSITQPSLSHAISQLEQELGTRLFEKKGRNVVLTRY
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHH
GKMFLPYVEESLKVLNEGVQRIQEVNGSRHGIIHLAYIYTMGSEFAPKLVRKFLDAYPDY
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHCCHHHHHHHHHHHHHCCCC
DIEFHFTVGTTGEIIDGLKDDKYDIVFSSYKDGEQDIDFKKIANQKLVLAVPMDHPLSIK
CEEEEEEECCCHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHCCCEEEEEECCCCCCCCC
DSVDLRDTIEYPQIYFEKGSGLRPVIDQMFEEIGQFPKVAFEMEEDSSMAGLVAQGFGIA
CCCCHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHCCCCEE
VMPDIPILRSLSVKTLDIYNPPYERAVYLATLKQRYLSPVAKAFIRFVIEETA
ECCCCCHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]