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The map label for this gene is argD [H]

Identifier: 238923973

GI number: 238923973

Start: 1499413

End: 1500630

Strand: Direct

Name: argD [H]

Synonym: EUBREC_1611

Alternate gene names: 238923973

Gene position: 1499413-1500630 (Clockwise)

Preceding gene: 238923972

Following gene: 238923974

Centisome position: 43.47

GC content: 45.89

Gene sequence:

>1218_bases
ATGAGCAATAATATGGATAAACAGTCATACATTGATGAGGCAGAAAAGGAGCTTCTTCACACCTACAACAGATTTTCACT
TGTACTTGATCACGGCGAGGGAGTACATCTTTATGATACAGATGGCAATGCATATCTGGACTTCGCTGCAGGAATAGCCG
TATGTGCACTTGGATACAGCAATGAGCACCACAAGGAGGCATTAAAGGCACAGGTTGATAAGCTTTTACATACATCAAAC
CTCTACTACAATGCGCCTGTCATCGAGGCGGCAGACAAGGTGCTTAATGCAAGTAAAATGGACCGTATTTTCTTTACAAA
CAGTGGTACAGAGGCTATTGAGGGAGCTATCAAGGCTGCAAAGAAATATGCCTTTACAAGAGACGGCCATGCAGGTCATG
AGATAATTGCCATGAACCATTCCTTCCACGGAAGAAGCATCGGAGCGCTTTCTGTCACCGGCAATGCACATTATCAGGAG
CCGTTTGAGCCACTTATGCCGGGCGTTAAATTTGCAGATTTCAATGATTTAGAGAGCGTTAAGGCTCAGGTGACAGACAA
AACCTGCGCCATTATTATGGAAACTATTCAGGGTGAGGGTGGTATTTACCCGGCAAAGAAGGAGTTTATCGAGGGAGTGA
GAGCTCTCTGCGATGAAAAGGATATTCTTCTTATTCTTGACGAGATACAGTGCGGCATGGGCAGAAGTGGCGAAATGTTC
GCATGGCAGAACTATGATGTGAAGCCTGATATCATGACCTGTGCGAAGGCACTCGGCTGTGGTGTGCCTGTTGGTGCATT
TCTTATGACACAGAGGGTGGCAGACAAATCCCTTGCACCGGGCGACCATGGTACCACATACGGCGGCAATCCGTTCGTAG
GAGCCGCAGTAAGTGCAGTGTTTGATGAGTTTAAGCGTCTTGATATAGTAAGCCATGTAAAGGAGGTTGCACCTTACCTG
GAGAAGAGGCTTGATGAGCTTGTTGCAAAATTCGACTGTCTCACAGCCAGAAGGGGTATGGGACTCATGCAGGGCGTGGA
GTGCAGCCTTCCTGTAGGAAAGGTCTCAGCAGAGACTTTAAATCAAGGCCTTATAGTCATTACGGCAGGCAGCAATGTGC
TTAGATTTGTGCCTCCTCTTGTTATCGAAAAGAGTGATGTTGACGAAATGATAGAAAAACTTGAAACAACACTTGTAATA
CTGTCAAAAAGTCTGTAA

Upstream 100 bases:

>100_bases
ATTCTTGATGGACGTATCGCACACTGCTTACTGCTTGAGATATTCACAAACAGAGGAATCGGAACAGCTATTCTTGGAGA
TTCGGAGGAGAAATTTAACA

Downstream 100 bases:

>100_bases
AATAAAGAGGACATCGATTTCTCCTTTGAGATTATGATATTAATCAAAGGAGACCATATGAAAAAAATAATATTATTAAG
TGCGTTTATTTTAACAATAG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSNNMDKQSYIDEAEKELLHTYNRFSLVLDHGEGVHLYDTDGNAYLDFAAGIAVCALGYSNEHHKEALKAQVDKLLHTSN
LYYNAPVIEAADKVLNASKMDRIFFTNSGTEAIEGAIKAAKKYAFTRDGHAGHEIIAMNHSFHGRSIGALSVTGNAHYQE
PFEPLMPGVKFADFNDLESVKAQVTDKTCAIIMETIQGEGGIYPAKKEFIEGVRALCDEKDILLILDEIQCGMGRSGEMF
AWQNYDVKPDIMTCAKALGCGVPVGAFLMTQRVADKSLAPGDHGTTYGGNPFVGAAVSAVFDEFKRLDIVSHVKEVAPYL
EKRLDELVAKFDCLTARRGMGLMQGVECSLPVGKVSAETLNQGLIVITAGSNVLRFVPPLVIEKSDVDEMIEKLETTLVI
LSKSL

Sequences:

>Translated_405_residues
MSNNMDKQSYIDEAEKELLHTYNRFSLVLDHGEGVHLYDTDGNAYLDFAAGIAVCALGYSNEHHKEALKAQVDKLLHTSN
LYYNAPVIEAADKVLNASKMDRIFFTNSGTEAIEGAIKAAKKYAFTRDGHAGHEIIAMNHSFHGRSIGALSVTGNAHYQE
PFEPLMPGVKFADFNDLESVKAQVTDKTCAIIMETIQGEGGIYPAKKEFIEGVRALCDEKDILLILDEIQCGMGRSGEMF
AWQNYDVKPDIMTCAKALGCGVPVGAFLMTQRVADKSLAPGDHGTTYGGNPFVGAAVSAVFDEFKRLDIVSHVKEVAPYL
EKRLDELVAKFDCLTARRGMGLMQGVECSLPVGKVSAETLNQGLIVITAGSNVLRFVPPLVIEKSDVDEMIEKLETTLVI
LSKSL
>Mature_404_residues
SNNMDKQSYIDEAEKELLHTYNRFSLVLDHGEGVHLYDTDGNAYLDFAAGIAVCALGYSNEHHKEALKAQVDKLLHTSNL
YYNAPVIEAADKVLNASKMDRIFFTNSGTEAIEGAIKAAKKYAFTRDGHAGHEIIAMNHSFHGRSIGALSVTGNAHYQEP
FEPLMPGVKFADFNDLESVKAQVTDKTCAIIMETIQGEGGIYPAKKEFIEGVRALCDEKDILLILDEIQCGMGRSGEMFA
WQNYDVKPDIMTCAKALGCGVPVGAFLMTQRVADKSLAPGDHGTTYGGNPFVGAAVSAVFDEFKRLDIVSHVKEVAPYLE
KRLDELVAKFDCLTARRGMGLMQGVECSLPVGKVSAETLNQGLIVITAGSNVLRFVPPLVIEKSDVDEMIEKLETTLVIL
SKSL

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=388, Percent_Identity=31.4432989690722, Blast_Score=202, Evalue=5e-52,
Organism=Homo sapiens, GI284507298, Length=301, Percent_Identity=32.2259136212625, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI13994255, Length=433, Percent_Identity=28.8683602771363, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI37574042, Length=413, Percent_Identity=27.1186440677966, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI226442705, Length=411, Percent_Identity=27.4939172749392, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI226442709, Length=382, Percent_Identity=28.0104712041885, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI24119277, Length=407, Percent_Identity=23.8329238329238, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1788044, Length=400, Percent_Identity=38.5, Blast_Score=302, Evalue=2e-83,
Organism=Escherichia coli, GI1789759, Length=395, Percent_Identity=39.746835443038, Blast_Score=296, Evalue=1e-81,
Organism=Escherichia coli, GI145693181, Length=386, Percent_Identity=33.160621761658, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1787560, Length=431, Percent_Identity=31.322505800464, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1789016, Length=395, Percent_Identity=30.8860759493671, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1786991, Length=412, Percent_Identity=25.7281553398058, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786349, Length=339, Percent_Identity=31.2684365781711, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25144271, Length=412, Percent_Identity=30.5825242718447, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI32564660, Length=435, Percent_Identity=29.4252873563218, Blast_Score=165, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI25144274, Length=297, Percent_Identity=30.976430976431, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI71992977, Length=420, Percent_Identity=24.7619047619048, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17541228, Length=448, Percent_Identity=26.7857142857143, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71981843, Length=182, Percent_Identity=28.5714285714286, Blast_Score=95, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6324432, Length=394, Percent_Identity=39.8477157360406, Blast_Score=283, Evalue=5e-77,
Organism=Saccharomyces cerevisiae, GI6323470, Length=423, Percent_Identity=27.8959810874704, Blast_Score=176, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6324386, Length=395, Percent_Identity=25.8227848101266, Blast_Score=99, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6321456, Length=432, Percent_Identity=24.3055555555556, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21357415, Length=386, Percent_Identity=29.0155440414508, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI161085790, Length=434, Percent_Identity=29.0322580645161, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI28574759, Length=423, Percent_Identity=28.6052009456265, Blast_Score=158, Evalue=8e-39,
Organism=Drosophila melanogaster, GI21356575, Length=417, Percent_Identity=25.8992805755396, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281366494, Length=422, Percent_Identity=21.8009478672986, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24667139, Length=422, Percent_Identity=21.8009478672986, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24667143, Length=422, Percent_Identity=21.8009478672986, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 44220; Mature: 44089

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNMDKQSYIDEAEKELLHTYNRFSLVLDHGEGVHLYDTDGNAYLDFAAGIAVCALGYS
CCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCCCEEEHHHHHHHHHHCCCC
NEHHKEALKAQVDKLLHTSNLYYNAPVIEAADKVLNASKMDRIFFTNSGTEAIEGAIKAA
CHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHCHHHCCEEEEECCCHHHHHHHHHHH
KKYAFTRDGHAGHEIIAMNHSFHGRSIGALSVTGNAHYQEPFEPLMPGVKFADFNDLESV
HHHHCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCHHHHCCCCEECCCCHHHHH
KAQVTDKTCAIIMETIQGEGGIYPAKKEFIEGVRALCDEKDILLILDEIQCGMGRSGEMF
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECHHCCCCCCCCEE
AWQNYDVKPDIMTCAKALGCGVPVGAFLMTQRVADKSLAPGDHGTTYGGNPFVGAAVSAV
EECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
FDEFKRLDIVSHVKEVAPYLEKRLDELVAKFDCLTARRGMGLMQGVECSLPVGKVSAETL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCHHHH
NQGLIVITAGSNVLRFVPPLVIEKSDVDEMIEKLETTLVILSKSL
CCCEEEEECCCCHHHHCCCHHCCCCCHHHHHHHHHHHHHEEECCC
>Mature Secondary Structure 
SNNMDKQSYIDEAEKELLHTYNRFSLVLDHGEGVHLYDTDGNAYLDFAAGIAVCALGYS
CCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEECCCCEEEHHHHHHHHHHCCCC
NEHHKEALKAQVDKLLHTSNLYYNAPVIEAADKVLNASKMDRIFFTNSGTEAIEGAIKAA
CHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHCHHHCCEEEEECCCHHHHHHHHHHH
KKYAFTRDGHAGHEIIAMNHSFHGRSIGALSVTGNAHYQEPFEPLMPGVKFADFNDLESV
HHHHCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCHHHHCCCCEECCCCHHHHH
KAQVTDKTCAIIMETIQGEGGIYPAKKEFIEGVRALCDEKDILLILDEIQCGMGRSGEMF
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECHHCCCCCCCCEE
AWQNYDVKPDIMTCAKALGCGVPVGAFLMTQRVADKSLAPGDHGTTYGGNPFVGAAVSAV
EECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
FDEFKRLDIVSHVKEVAPYLEKRLDELVAKFDCLTARRGMGLMQGVECSLPVGKVSAETL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCHHHH
NQGLIVITAGSNVLRFVPPLVIEKSDVDEMIEKLETTLVILSKSL
CCCEEEEECCCCHHHHCCCHHCCCCCHHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10588044; 10688204 [H]