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The map label for this gene is comEA [H]

Identifier: 238923974

GI number: 238923974

Start: 1500664

End: 1501395

Strand: Direct

Name: comEA [H]

Synonym: EUBREC_1612

Alternate gene names: 238923974

Gene position: 1500664-1501395 (Clockwise)

Preceding gene: 238923973

Following gene: 238923975

Centisome position: 43.5

GC content: 44.4

Gene sequence:

>732_bases
ATGATATTAATCAAAGGAGACCATATGAAAAAAATAATATTATTAAGTGCGTTTATTTTAACAATAGCGTTTGGCCTTTG
CGGCTGTAAAAAGGATGATGCCACAGTTCATTTTGCTTCTGAAACGGAGCAGACTGCTGTGGTTTCAAGTGATGTAAACA
GACAGCCTGTTGATTCCAAGGAGAAGAAGGCTTCATCCGATGGAGAACAGGAGCAGAAGGCAAAAGACACAGCAGATGAC
ACTGATGAATCTACTGAGTGGTGCGTCTATATCTGTGGTCAGGTTGCCAATCCCGGTGTATACAGAGTAAAGCCGGGCGC
GAGAGTTTGTGAGCTCGTTGATATGGCAGGAGGCATGCTGGATACAGCTGACAAAAGCTTTTGGAATCTGGCATCAGAGT
TGTATGATGGGCAGATGCTGTATTTCCCGACTGTAGAGGAGCTTAAGTCGGATCACATACCTGAGGGCACATATACCACC
GGCATAGATGGCTCGCTGATGAAGGGCGGCGCTGAGGAACATATAGGCGTAAAGGATGGCAAGCTCAATATCAATACCGC
AACTGTCGAGCAGCTAATGGCTCTTTCCGGAATTGGTGAGAGCAAGGCAAAGAGTATTGTTGAAGATCGCGCCAAAAATG
GATTGTTTTCTTCGATTGAGGATATCACGAGGGTGTCCGGCATCGGTGAAACGATGTTTAATAAAATAAAAGATGATATA
ACAGTAAATTAG

Upstream 100 bases:

>100_bases
GAGTGATGTTGACGAAATGATAGAAAAACTTGAAACAACACTTGTAATACTGTCAAAAAGTCTGTAAAATAAAGAGGACA
TCGATTTCTCCTTTGAGATT

Downstream 100 bases:

>100_bases
GAGTGTATAAATGGCAAAAAAAGTGCTGGTCGTTGACGACGAAAAGTTAATTGTAAAAGGAATACGTTTCAGTCTGCTGC
AGGATGGCATGGAAGTAGAC

Product: unspecific high-affinity DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MILIKGDHMKKIILLSAFILTIAFGLCGCKKDDATVHFASETEQTAVVSSDVNRQPVDSKEKKASSDGEQEQKAKDTADD
TDESTEWCVYICGQVANPGVYRVKPGARVCELVDMAGGMLDTADKSFWNLASELYDGQMLYFPTVEELKSDHIPEGTYTT
GIDGSLMKGGAEEHIGVKDGKLNINTATVEQLMALSGIGESKAKSIVEDRAKNGLFSSIEDITRVSGIGETMFNKIKDDI
TVN

Sequences:

>Translated_243_residues
MILIKGDHMKKIILLSAFILTIAFGLCGCKKDDATVHFASETEQTAVVSSDVNRQPVDSKEKKASSDGEQEQKAKDTADD
TDESTEWCVYICGQVANPGVYRVKPGARVCELVDMAGGMLDTADKSFWNLASELYDGQMLYFPTVEELKSDHIPEGTYTT
GIDGSLMKGGAEEHIGVKDGKLNINTATVEQLMALSGIGESKAKSIVEDRAKNGLFSSIEDITRVSGIGETMFNKIKDDI
TVN
>Mature_243_residues
MILIKGDHMKKIILLSAFILTIAFGLCGCKKDDATVHFASETEQTAVVSSDVNRQPVDSKEKKASSDGEQEQKAKDTADD
TDESTEWCVYICGQVANPGVYRVKPGARVCELVDMAGGMLDTADKSFWNLASELYDGQMLYFPTVEELKSDHIPEGTYTT
GIDGSLMKGGAEEHIGVKDGKLNINTATVEQLMALSGIGESKAKSIVEDRAKNGLFSSIEDITRVSGIGETMFNKIKDDI
TVN

Specific function: Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding may be indirect [H]

COG id: COG1555

COG function: function code L; DNA uptake protein and related DNA-binding proteins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HhH domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004787
- InterPro:   IPR004509
- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR019554 [H]

Pfam domain/function: PF00633 HHH; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 26342; Mature: 26342

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILIKGDHMKKIILLSAFILTIAFGLCGCKKDDATVHFASETEQTAVVSSDVNRQPVDSK
CEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHCCCCCCCCCCH
EKKASSDGEQEQKAKDTADDTDESTEWCVYICGQVANPGVYRVKPGARVCELVDMAGGML
HHHCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHHHCCCCH
DTADKSFWNLASELYDGQMLYFPTVEELKSDHIPEGTYTTGIDGSLMKGGAEEHIGVKDG
HHHHHHHHHHHHHHHCCCEEECCCHHHHHHCCCCCCCEECCCCCHHHCCCCHHCCCCCCC
KLNINTATVEQLMALSGIGESKAKSIVEDRAKNGLFSSIEDITRVSGIGETMFNKIKDDI
EEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHCC
TVN
CCC
>Mature Secondary Structure
MILIKGDHMKKIILLSAFILTIAFGLCGCKKDDATVHFASETEQTAVVSSDVNRQPVDSK
CEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHCCCCCCCCCCH
EKKASSDGEQEQKAKDTADDTDESTEWCVYICGQVANPGVYRVKPGARVCELVDMAGGML
HHHCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEECCCHHHHHHHHHCCCCH
DTADKSFWNLASELYDGQMLYFPTVEELKSDHIPEGTYTTGIDGSLMKGGAEEHIGVKDG
HHHHHHHHHHHHHHHCCCEEECCCHHHHHHCCCCCCCEECCCCCHHHCCCCHHCCCCCCC
KLNINTATVEQLMALSGIGESKAKSIVEDRAKNGLFSSIEDITRVSGIGETMFNKIKDDI
EEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHCC
TVN
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377; 7768800 [H]