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The map label for this gene is argB [H]

Identifier: 238923972

GI number: 238923972

Start: 1498521

End: 1499423

Strand: Direct

Name: argB [H]

Synonym: EUBREC_1610

Alternate gene names: 238923972

Gene position: 1498521-1499423 (Clockwise)

Preceding gene: 238923971

Following gene: 238923973

Centisome position: 43.44

GC content: 43.41

Gene sequence:

>903_bases
ATGGCAGATAAGAACATGGAACAGGTAATGGAAAAGGCACAGGTGCTCATAGAGGCACTTCCGTATATACAGAGATTTAA
CAGAAAGATTATCGTTGTAAAGTACGGCGGATCTGCAATGGTTGACGAACAGCTTAAAAAGCAGGTGATCCAGGATGTCA
CACTTCTCAAGCTGGTCGGCTTCAAGCCTATCATCGTACACGGCGGAGGCAAGGAAATCAGCAAATGGGTAGGAAAGGTC
GGCATGGAGCCTGTATTCGTAAACGGACTCAGAAAGACTGATGCCGATACAATGGAGATTGCCGAGATGGTATTGAATAA
GGTAAACAAATCTCTCGTTACACTCGTTGAGGAGCTTGGTGTGCAGGCTGTCGGAGTGAGTGGCAAGGACGGTGGCCTCT
TAAAGGTAAAGAAAAAGTATTCAAACGGAGAGGATATAGGCTTTGTCGGTGAAATCACTGATGTCAATCCAAAAATTCTT
TATGACCTGCTTGAGAAGGATTTTCTTCCAATTGTGTGTCCAATCGGTCTTGATGATGAATACAATACATACAATATCAA
TGCAGATGATGCAGCATGCGCTATCGCCAGAGCAGTTTCAGCAGAAAAGCTTGCATTCCTCACGGATATCGAGGGTGTAT
ACAAAGACCCTTCAGATAAGAATACACTTATTTCAGAGCTTACAGTCTCAGATGCAAAGAAGCTTATAGGTGATGGCTTT
ATCGGCGGAGGCATGCTTCCTAAGCTCAACAACTGCATAGATGCTATCGATAACGGAGTTTCAAGAGTTCATATTCTTGA
TGGACGTATCGCACACTGCTTACTGCTTGAGATATTCACAAACAGAGGAATCGGAACAGCTATTCTTGGAGATTCGGAGG
AGAAATTTAACAATGAGCAATAA

Upstream 100 bases:

>100_bases
GGAAGGAAGAGGGATGGACATTCAGAGAAGACTTAAACTACTATGATTTCACACTTAACGAAGAAAATATAACAAGATTT
AACAAATAAGGAGCAGTACA

Downstream 100 bases:

>100_bases
TATGGATAAACAGTCATACATTGATGAGGCAGAAAAGGAGCTTCTTCACACCTACAACAGATTTTCACTTGTACTTGATC
ACGGCGAGGGAGTACATCTT

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MADKNMEQVMEKAQVLIEALPYIQRFNRKIIVVKYGGSAMVDEQLKKQVIQDVTLLKLVGFKPIIVHGGGKEISKWVGKV
GMEPVFVNGLRKTDADTMEIAEMVLNKVNKSLVTLVEELGVQAVGVSGKDGGLLKVKKKYSNGEDIGFVGEITDVNPKIL
YDLLEKDFLPIVCPIGLDDEYNTYNINADDAACAIARAVSAEKLAFLTDIEGVYKDPSDKNTLISELTVSDAKKLIGDGF
IGGGMLPKLNNCIDAIDNGVSRVHILDGRIAHCLLLEIFTNRGIGTAILGDSEEKFNNEQ

Sequences:

>Translated_300_residues
MADKNMEQVMEKAQVLIEALPYIQRFNRKIIVVKYGGSAMVDEQLKKQVIQDVTLLKLVGFKPIIVHGGGKEISKWVGKV
GMEPVFVNGLRKTDADTMEIAEMVLNKVNKSLVTLVEELGVQAVGVSGKDGGLLKVKKKYSNGEDIGFVGEITDVNPKIL
YDLLEKDFLPIVCPIGLDDEYNTYNINADDAACAIARAVSAEKLAFLTDIEGVYKDPSDKNTLISELTVSDAKKLIGDGF
IGGGMLPKLNNCIDAIDNGVSRVHILDGRIAHCLLLEIFTNRGIGTAILGDSEEKFNNEQ
>Mature_299_residues
ADKNMEQVMEKAQVLIEALPYIQRFNRKIIVVKYGGSAMVDEQLKKQVIQDVTLLKLVGFKPIIVHGGGKEISKWVGKVG
MEPVFVNGLRKTDADTMEIAEMVLNKVNKSLVTLVEELGVQAVGVSGKDGGLLKVKKKYSNGEDIGFVGEITDVNPKILY
DLLEKDFLPIVCPIGLDDEYNTYNINADDAACAIARAVSAEKLAFLTDIEGVYKDPSDKNTLISELTVSDAKKLIGDGFI
GGGMLPKLNNCIDAIDNGVSRVHILDGRIAHCLLLEIFTNRGIGTAILGDSEEKFNNEQ

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI145693208, Length=261, Percent_Identity=32.183908045977, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789181, Length=303, Percent_Identity=23.1023102310231, Blast_Score=86, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320913, Length=290, Percent_Identity=24.4827586206897, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 32727; Mature: 32596

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKNMEQVMEKAQVLIEALPYIQRFNRKIIVVKYGGSAMVDEQLKKQVIQDVTLLKLVG
CCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHC
FKPIIVHGGGKEISKWVGKVGMEPVFVNGLRKTDADTMEIAEMVLNKVNKSLVTLVEELG
CCEEEEECCCHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
VQAVGVSGKDGGLLKVKKKYSNGEDIGFVGEITDVNPKILYDLLEKDFLPIVCPIGLDDE
CEEEECCCCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEECCCCCC
YNTYNINADDAACAIARAVSAEKLAFLTDIEGVYKDPSDKNTLISELTVSDAKKLIGDGF
CCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
IGGGMLPKLNNCIDAIDNGVSRVHILDGRIAHCLLLEIFTNRGIGTAILGDSEEKFNNEQ
CCCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEECCCHHHCCCCC
>Mature Secondary Structure 
ADKNMEQVMEKAQVLIEALPYIQRFNRKIIVVKYGGSAMVDEQLKKQVIQDVTLLKLVG
CCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHC
FKPIIVHGGGKEISKWVGKVGMEPVFVNGLRKTDADTMEIAEMVLNKVNKSLVTLVEELG
CCEEEEECCCHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
VQAVGVSGKDGGLLKVKKKYSNGEDIGFVGEITDVNPKILYDLLEKDFLPIVCPIGLDDE
CEEEECCCCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEECCCCCC
YNTYNINADDAACAIARAVSAEKLAFLTDIEGVYKDPSDKNTLISELTVSDAKKLIGDGF
CCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
IGGGMLPKLNNCIDAIDNGVSRVHILDGRIAHCLLLEIFTNRGIGTAILGDSEEKFNNEQ
CCCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEECCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA