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The map label for this gene is trxB [C]

Identifier: 238923466

GI number: 238923466

Start: 994018

End: 994875

Strand: Direct

Name: trxB [C]

Synonym: EUBREC_1086

Alternate gene names: 238923466

Gene position: 994018-994875 (Clockwise)

Preceding gene: 238923465

Following gene: 238923470

Centisome position: 28.81

GC content: 43.82

Gene sequence:

>858_bases
ATGTACGATAGTATAATAATAGGAACAGGTCCTGCCGGACTGTCGGCAGCCCTGAATTTAAAAACATATAAAAAGGATTT
TATCTGGTTTGGTTCGAAGAACCTAAGCGAAAAGGTGCAAAAGGCAGAGAAAATCACAAACTATCCCGGATTTCCACAGA
TAAGCGGACAGGAGCTGTTTGAACGCTTTGACGCTCATAGGAGAGCTGCGGGAATTGATATAACAGAAAAGACTGTGACC
AATATCATGCCTGCAGGAAACGGCTTTATGGTGCTTGCAGACAATGAGATGTATGAGGCAAGGACTCTCATACTTTGCAT
GGGTGTGATGTCTGCAAAGCAGCTGGACAGGGAGGATGAGCTGCTTGGAAAAAGGCTCAGCTATTGTGCCACCTGTGATG
GCATGTTTTACAAGGATAAGAGGATAGCTGTCATATGCAATGACAAAAAGTATGAGCATGAGGTTAAATATCTTGCGGAT
CTTGCAGCAGAGGTATTGTATTTCCCAGCCTATAATGACAGCGAAATAGAGCTTACAAATGTAAAGATATCAAAGGATGT
ACCTATAGCATTAATCGGAGACTCATTTGTGGAAGGAATTACGCTTCGAAGCGGAAAGACTGAGAGCGTAGACGGAGTAT
TCTGCCTCAGGAACGCCATCGCACCATCAAAGCTTATGCCGCAGCTTGAAATAGAAAACGGACATATATTGGTGGATAGA
GCCCAACAGACAAATGTGGCAGGCTGTTTTGCGGCAGGAGACTGCACAGGCAGGCCATACCAGTATACGAAGGCTGTCGG
AGAAGGAAATGTGGCAGCACATTCGTGTATACAATATCTTAGTAAATCAGAAAAATAA

Upstream 100 bases:

>100_bases
ATCATCGATGCATACTTGCATGCAATTCGATGTATACCTTAGTGCCCACACTATATATAAGGTCTAAATATATACAAACA
TTTGGTACAAGGAGCATAGC

Downstream 100 bases:

>100_bases
TATGGCAATGGCATAGAGGTCGGTTAAAGCATGTTAAAGGCAACTACAGCCACTTACCATTGAGAAGATATTGATTTCTC
TCAGCTCCGACTGAGACAAA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MYDSIIIGTGPAGLSAALNLKTYKKDFIWFGSKNLSEKVQKAEKITNYPGFPQISGQELFERFDAHRRAAGIDITEKTVT
NIMPAGNGFMVLADNEMYEARTLILCMGVMSAKQLDREDELLGKRLSYCATCDGMFYKDKRIAVICNDKKYEHEVKYLAD
LAAEVLYFPAYNDSEIELTNVKISKDVPIALIGDSFVEGITLRSGKTESVDGVFCLRNAIAPSKLMPQLEIENGHILVDR
AQQTNVAGCFAAGDCTGRPYQYTKAVGEGNVAAHSCIQYLSKSEK

Sequences:

>Translated_285_residues
MYDSIIIGTGPAGLSAALNLKTYKKDFIWFGSKNLSEKVQKAEKITNYPGFPQISGQELFERFDAHRRAAGIDITEKTVT
NIMPAGNGFMVLADNEMYEARTLILCMGVMSAKQLDREDELLGKRLSYCATCDGMFYKDKRIAVICNDKKYEHEVKYLAD
LAAEVLYFPAYNDSEIELTNVKISKDVPIALIGDSFVEGITLRSGKTESVDGVFCLRNAIAPSKLMPQLEIENGHILVDR
AQQTNVAGCFAAGDCTGRPYQYTKAVGEGNVAAHSCIQYLSKSEK
>Mature_285_residues
MYDSIIIGTGPAGLSAALNLKTYKKDFIWFGSKNLSEKVQKAEKITNYPGFPQISGQELFERFDAHRRAAGIDITEKTVT
NIMPAGNGFMVLADNEMYEARTLILCMGVMSAKQLDREDELLGKRLSYCATCDGMFYKDKRIAVICNDKKYEHEVKYLAD
LAAEVLYFPAYNDSEIELTNVKISKDVPIALIGDSFVEGITLRSGKTESVDGVFCLRNAIAPSKLMPQLEIENGHILVDR
AQQTNVAGCFAAGDCTGRPYQYTKAVGEGNVAAHSCIQYLSKSEK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=306, Percent_Identity=28.4313725490196, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87081763, Length=266, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 31503; Mature: 31503

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDSIIIGTGPAGLSAALNLKTYKKDFIWFGSKNLSEKVQKAEKITNYPGFPQISGQELF
CCCCEEEECCCCCCCEEEEEEECCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHH
ERFDAHRRAAGIDITEKTVTNIMPAGNGFMVLADNEMYEARTLILCMGVMSAKQLDREDE
HHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHH
LLGKRLSYCATCDGMFYKDKRIAVICNDKKYEHEVKYLADLAAEVLYFPAYNDSEIELTN
HHHHHHHHHHCCCCCEEECCEEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCCEEEEEE
VKISKDVPIALIGDSFVEGITLRSGKTESVDGVFCLRNAIAPSKLMPQLEIENGHILVDR
EEEECCCCEEEECCHHHCCEEECCCCCCCCCHHHHHHHCCCHHHCCCEEEECCCEEEEEC
AQQTNVAGCFAAGDCTGRPYQYTKAVGEGNVAAHSCIQYLSKSEK
CCCCCCEEEEECCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYDSIIIGTGPAGLSAALNLKTYKKDFIWFGSKNLSEKVQKAEKITNYPGFPQISGQELF
CCCCEEEECCCCCCCEEEEEEECCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHH
ERFDAHRRAAGIDITEKTVTNIMPAGNGFMVLADNEMYEARTLILCMGVMSAKQLDREDE
HHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHH
LLGKRLSYCATCDGMFYKDKRIAVICNDKKYEHEVKYLADLAAEVLYFPAYNDSEIELTN
HHHHHHHHHHCCCCCEEECCEEEEEECCCCHHHHHHHHHHHHHHHEEECCCCCCEEEEEE
VKISKDVPIALIGDSFVEGITLRSGKTESVDGVFCLRNAIAPSKLMPQLEIENGHILVDR
EEEECCCCEEEECCHHHCCEEECCCCCCCCCHHHHHHHCCCHHHCCCEEEECCCEEEEEC
AQQTNVAGCFAAGDCTGRPYQYTKAVGEGNVAAHSCIQYLSKSEK
CCCCCCEEEEECCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]