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The map label for this gene is yofA [H]

Identifier: 238923470

GI number: 238923470

Start: 998612

End: 999508

Strand: Direct

Name: yofA [H]

Synonym: EUBREC_1090

Alternate gene names: 238923470

Gene position: 998612-999508 (Clockwise)

Preceding gene: 238923466

Following gene: 238923471

Centisome position: 28.95

GC content: 45.26

Gene sequence:

>897_bases
ATGGATATAAATTTTGAGTACTACAAGATATTTTATTATGTTGCAAAATACTGCAATTTCACAAAGGCTGCGAGGGCGCT
CGGAAACAGCCAGCCAAATGTAACCCGCGCCATGAACAATTTAGAACAGCAGATAAACAGCATACTTTTTATCAGAAATA
ACAGAGGTGTGCAGCTCACACCGGAGGGAGAGCGTCTGTACGCGCATGTATCTGCAGCGATGTCACAGATACTTGCTGCG
GAGGAGGAGCTGTCAGACAGCATAGGACTGTCACACGGAAGCGTATCAATAGGAGCCAGTGAGACAGCTCTAAACATATA
TCTGCTTGACAGGCTAAAACCTTTTCACATGGCATATCCGGGTATCAGGCTTAAGATATATAATCACTCCACCCCACAGG
CTATAAATGCCGTAAAAAACGGCATGATTGATTTTGCAGTGGTATCGACACCGGCTGAGGTGGAGGCCCCTCTTAAGATG
ATAAAGCTTGGTTCGTTTCAGGAGATTCTTGTGGGTGGAACCACCTTTACTGCACTCGGAAGCCAGACTCTGTCATTAAA
GGAGCTGCATAATTATCCGCTTATCGGACTGGGGCGGGAGACCATGACATTTCAGTTTTTTAACAGGCTTTTTATGTCAC
ACGGACTTGAATTTGCGCCTGATACAGAGACCGCAACGACAGATCAGATACTGCCACTTGTGAAAAGTGAGCTTGGTCTT
GCCTTTATGCCAAAGCCTATGGCAGAGGCTGCGATAGCAAATCGCGAGATTGTAGAGATAGCTCTGGAGGAGGAGATACC
GCAGAGAAATATATGTATGGTATATGATATACATCAACCGATTAGTGCGGCGGCAAGAGAGTTAAAGAAAGTTATATCAG
ACAGCCATAAGGTGTGA

Upstream 100 bases:

>100_bases
ATAATTGATATAATTGAAATATCATATTATTATATCATTAGTATCTGTGTATTACCGGAAAAATGACCGGTAAAACGATA
ATAAAAAGGAGGCTTTGAAT

Downstream 100 bases:

>100_bases
TTGGCAGTAGGTGGGATATACATAGGTAACCGGCAGGTTACATATTGCAACAGGTATGTTACACATTGGCAGGTTTGTAA
CTTACATCTCGTTTAATACT

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MDINFEYYKIFYYVAKYCNFTKAARALGNSQPNVTRAMNNLEQQINSILFIRNNRGVQLTPEGERLYAHVSAAMSQILAA
EEELSDSIGLSHGSVSIGASETALNIYLLDRLKPFHMAYPGIRLKIYNHSTPQAINAVKNGMIDFAVVSTPAEVEAPLKM
IKLGSFQEILVGGTTFTALGSQTLSLKELHNYPLIGLGRETMTFQFFNRLFMSHGLEFAPDTETATTDQILPLVKSELGL
AFMPKPMAEAAIANREIVEIALEEEIPQRNICMVYDIHQPISAAARELKKVISDSHKV

Sequences:

>Translated_298_residues
MDINFEYYKIFYYVAKYCNFTKAARALGNSQPNVTRAMNNLEQQINSILFIRNNRGVQLTPEGERLYAHVSAAMSQILAA
EEELSDSIGLSHGSVSIGASETALNIYLLDRLKPFHMAYPGIRLKIYNHSTPQAINAVKNGMIDFAVVSTPAEVEAPLKM
IKLGSFQEILVGGTTFTALGSQTLSLKELHNYPLIGLGRETMTFQFFNRLFMSHGLEFAPDTETATTDQILPLVKSELGL
AFMPKPMAEAAIANREIVEIALEEEIPQRNICMVYDIHQPISAAARELKKVISDSHKV
>Mature_298_residues
MDINFEYYKIFYYVAKYCNFTKAARALGNSQPNVTRAMNNLEQQINSILFIRNNRGVQLTPEGERLYAHVSAAMSQILAA
EEELSDSIGLSHGSVSIGASETALNIYLLDRLKPFHMAYPGIRLKIYNHSTPQAINAVKNGMIDFAVVSTPAEVEAPLKM
IKLGSFQEILVGGTTFTALGSQTLSLKELHNYPLIGLGRETMTFQFFNRLFMSHGLEFAPDTETATTDQILPLVKSELGL
AFMPKPMAEAAIANREIVEIALEEEIPQRNICMVYDIHQPISAAARELKKVISDSHKV

Specific function: Regulates expression of the cell division protein ftsW, and is essential for cell viability during stationary phase [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=139, Percent_Identity=28.0575539568345, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI157672245, Length=239, Percent_Identity=25.1046025104602, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786401, Length=273, Percent_Identity=24.9084249084249, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787530, Length=253, Percent_Identity=24.901185770751, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789204, Length=287, Percent_Identity=23.6933797909408, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081904, Length=145, Percent_Identity=30.3448275862069, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787879, Length=300, Percent_Identity=23.6666666666667, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789506, Length=282, Percent_Identity=24.113475177305, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787128, Length=174, Percent_Identity=27.0114942528736, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788481, Length=286, Percent_Identity=22.027972027972, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI145693105, Length=282, Percent_Identity=23.4042553191489, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33132; Mature: 33132

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINFEYYKIFYYVAKYCNFTKAARALGNSQPNVTRAMNNLEQQINSILFIRNNRGVQLT
CCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEEECCCCEEEC
PEGERLYAHVSAAMSQILAAEEELSDSIGLSHGSVSIGASETALNIYLLDRLKPFHMAYP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCCCHHHCCCC
GIRLKIYNHSTPQAINAVKNGMIDFAVVSTPAEVEAPLKMIKLGSFQEILVGGTTFTALG
CEEEEEECCCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHCCCCCHHHHC
SQTLSLKELHNYPLIGLGRETMTFQFFNRLFMSHGLEFAPDTETATTDQILPLVKSELGL
CCCEEHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCC
AFMPKPMAEAAIANREIVEIALEEEIPQRNICMVYDIHQPISAAARELKKVISDSHKV
EECCCHHHHHHHCCCHHHEEEEHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDINFEYYKIFYYVAKYCNFTKAARALGNSQPNVTRAMNNLEQQINSILFIRNNRGVQLT
CCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEEECCCCEEEC
PEGERLYAHVSAAMSQILAAEEELSDSIGLSHGSVSIGASETALNIYLLDRLKPFHMAYP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCCCHHHCCCC
GIRLKIYNHSTPQAINAVKNGMIDFAVVSTPAEVEAPLKMIKLGSFQEILVGGTTFTALG
CEEEEEECCCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHCCCCCHHHHC
SQTLSLKELHNYPLIGLGRETMTFQFFNRLFMSHGLEFAPDTETATTDQILPLVKSELGL
CCCEEHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCC
AFMPKPMAEAAIANREIVEIALEEEIPQRNICMVYDIHQPISAAARELKKVISDSHKV
EECCCHHHHHHHCCCHHHEEEEHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA