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The map label for this gene is bcd [H]

Identifier: 238923142

GI number: 238923142

Start: 679828

End: 680997

Strand: Direct

Name: bcd [H]

Synonym: EUBREC_0735

Alternate gene names: 238923142

Gene position: 679828-680997 (Clockwise)

Preceding gene: 238923141

Following gene: 238923143

Centisome position: 19.71

GC content: 45.04

Gene sequence:

>1170_bases
ATGGATTTCACTTTAGATCAGAAACATGAGATGGCTCGCGACCTTTTCAAACAGTTCGCAGAGACAGAAGTTAAACCTCT
TGCACAGGAGACTGACGAGACAGAGGTATTCCCAGCAGAGACAGTTGCTAAGATGGGAAAATATGGATTCATGGGCATTC
CTGTACCAAAGGAGTACGGCGGACAGGGCTGTGATCCACTTACATACGTTATGTGTGTAGAAGAATTATCAAAGGTTTGT
GGTACAACAGGCGTTATTGTATCTGCTCATACATCACTTTGTATCGATCCTATTATGACATTCGGTACAGAGGAGCAGAA
GAAAAAATATGTTCCTGACCTTGCTTCAGGCAAGAAGATCGGTGCTTTCGGTCTTACTGAGCCGGGCGCTGGTACAGATG
CACAGGGATGTCAGACAAAGGCCGTTTTAGACGGAGACGAGTGGGTTCTTAACGGATCTAAGTGCTTCATCACAAACGGT
AAGGTTGCTGATGTTTACATCATCATCGCTATTACAAGCATCACAGAGGACAAGCGTGGACGCAAGAAGAAGAACTTCTC
TGCATTCATCGTAGACAAGGGAACACCTGGATTCTCATTCGGAACAAAAGAGAAGAAGATGGGTATCCGCGGATCATCTA
CATACGAGCTTATCTTCGAGGATGCACGTATTCCAAAGAATGCATTACTTGGAAAAGAGGGAAGAGGTTTCCCAATCGCT
ATGCATACACTTGATGGTGGACGTATCGGAATCGCTGCTCAGGCACTTGGTATTGCAGAGGGCGCATTAGAGAGAACTAT
CGAGTACACAAAGGAAAGAAAGCAGTTCGGCCGTTCAATCGCACAGCAGCAGAATACACAGTTCAAGCTTGCAGATATGG
CTACACGTATCGATGCAGCTAAGTATCTTGTATACGCAGCAGCTATGAAGAAGGCAGAGTTTGCTAAGAACCCTAAGGTT
TCTTACTCAGTAGATGCAGCAAAGGCTAAATTATTCGCAGCAGAGACAGCTATGGCTGTTACAACAGAGTGCGTTCAGTT
ATTCGGTGGATACGGATATATCCGTGAGTATGATGTAGAGCGTATGATGCGTGATGCTAAGATTACAGAGATCTACGAGG
GAACTTCAGAGGTTCAGCGTATGGTTATTTCAGGCTCATTACTCAGATAG

Upstream 100 bases:

>100_bases
CATATATACGTTATAAAATATAGGTCTTATGTAGCTTATATATAAACTATAAAGTTATATAAGAATTCAATAACAAAACA
AAAATCAAGGAGAATAAATC

Downstream 100 bases:

>100_bases
TTAAGAGAGCTATCATAACTGTAGAGCTACTTAGAATAAATAAAGGAGAACAAATACATGAATATCGTAGTATGTATTAA
ACAGGTTCCTGATACAAAGG

Product: butyryl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MDFTLDQKHEMARDLFKQFAETEVKPLAQETDETEVFPAETVAKMGKYGFMGIPVPKEYGGQGCDPLTYVMCVEELSKVC
GTTGVIVSAHTSLCIDPIMTFGTEEQKKKYVPDLASGKKIGAFGLTEPGAGTDAQGCQTKAVLDGDEWVLNGSKCFITNG
KVADVYIIIAITSITEDKRGRKKKNFSAFIVDKGTPGFSFGTKEKKMGIRGSSTYELIFEDARIPKNALLGKEGRGFPIA
MHTLDGGRIGIAAQALGIAEGALERTIEYTKERKQFGRSIAQQQNTQFKLADMATRIDAAKYLVYAAAMKKAEFAKNPKV
SYSVDAAKAKLFAAETAMAVTTECVQLFGGYGYIREYDVERMMRDAKITEIYEGTSEVQRMVISGSLLR

Sequences:

>Translated_389_residues
MDFTLDQKHEMARDLFKQFAETEVKPLAQETDETEVFPAETVAKMGKYGFMGIPVPKEYGGQGCDPLTYVMCVEELSKVC
GTTGVIVSAHTSLCIDPIMTFGTEEQKKKYVPDLASGKKIGAFGLTEPGAGTDAQGCQTKAVLDGDEWVLNGSKCFITNG
KVADVYIIIAITSITEDKRGRKKKNFSAFIVDKGTPGFSFGTKEKKMGIRGSSTYELIFEDARIPKNALLGKEGRGFPIA
MHTLDGGRIGIAAQALGIAEGALERTIEYTKERKQFGRSIAQQQNTQFKLADMATRIDAAKYLVYAAAMKKAEFAKNPKV
SYSVDAAKAKLFAAETAMAVTTECVQLFGGYGYIREYDVERMMRDAKITEIYEGTSEVQRMVISGSLLR
>Mature_389_residues
MDFTLDQKHEMARDLFKQFAETEVKPLAQETDETEVFPAETVAKMGKYGFMGIPVPKEYGGQGCDPLTYVMCVEELSKVC
GTTGVIVSAHTSLCIDPIMTFGTEEQKKKYVPDLASGKKIGAFGLTEPGAGTDAQGCQTKAVLDGDEWVLNGSKCFITNG
KVADVYIIIAITSITEDKRGRKKKNFSAFIVDKGTPGFSFGTKEKKMGIRGSSTYELIFEDARIPKNALLGKEGRGFPIA
MHTLDGGRIGIAAQALGIAEGALERTIEYTKERKQFGRSIAQQQNTQFKLADMATRIDAAKYLVYAAAMKKAEFAKNPKV
SYSVDAAKAKLFAAETAMAVTTECVQLFGGYGYIREYDVERMMRDAKITEIYEGTSEVQRMVISGSLLR

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=385, Percent_Identity=48.5714285714286, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI7656849, Length=371, Percent_Identity=39.8921832884097, Blast_Score=275, Evalue=5e-74,
Organism=Homo sapiens, GI226958412, Length=381, Percent_Identity=40.4199475065617, Blast_Score=275, Evalue=6e-74,
Organism=Homo sapiens, GI4501859, Length=381, Percent_Identity=38.5826771653543, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI226958414, Length=340, Percent_Identity=42.3529411764706, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI187960098, Length=385, Percent_Identity=37.9220779220779, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI76496475, Length=378, Percent_Identity=35.7142857142857, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=36.8700265251989, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI4557235, Length=378, Percent_Identity=35.7142857142857, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI4557231, Length=385, Percent_Identity=37.9220779220779, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI21361497, Length=361, Percent_Identity=37.9501385041551, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI4503943, Length=376, Percent_Identity=30.5851063829787, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI7669494, Length=366, Percent_Identity=30.8743169398907, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI48976061, Length=290, Percent_Identity=27.2413793103448, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI211971008, Length=290, Percent_Identity=27.2413793103448, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI38505218, Length=395, Percent_Identity=24.3037974683544, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI218563752, Length=245, Percent_Identity=27.3469387755102, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87081958, Length=391, Percent_Identity=30.4347826086957, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1786223, Length=390, Percent_Identity=28.7179487179487, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI87081702, Length=297, Percent_Identity=25.9259259259259, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082384, Length=275, Percent_Identity=23.6363636363636, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17569725, Length=389, Percent_Identity=42.6735218508997, Blast_Score=283, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI17534899, Length=389, Percent_Identity=40.8740359897172, Blast_Score=279, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17508101, Length=368, Percent_Identity=38.3152173913043, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17506239, Length=371, Percent_Identity=37.7358490566038, Blast_Score=261, Evalue=4e-70,
Organism=Caenorhabditis elegans, GI17538396, Length=387, Percent_Identity=37.2093023255814, Blast_Score=260, Evalue=9e-70,
Organism=Caenorhabditis elegans, GI17570075, Length=388, Percent_Identity=38.1443298969072, Blast_Score=259, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI17533517, Length=371, Percent_Identity=37.466307277628, Blast_Score=251, Evalue=5e-67,
Organism=Caenorhabditis elegans, GI71985184, Length=357, Percent_Identity=38.0952380952381, Blast_Score=247, Evalue=6e-66,
Organism=Caenorhabditis elegans, GI71990804, Length=286, Percent_Identity=40.9090909090909, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17534353, Length=384, Percent_Identity=33.8541666666667, Blast_Score=204, Evalue=9e-53,
Organism=Caenorhabditis elegans, GI71985192, Length=278, Percent_Identity=39.2086330935252, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17505929, Length=380, Percent_Identity=29.7368421052632, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17551932, Length=380, Percent_Identity=28.9473684210526, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI32563615, Length=234, Percent_Identity=38.034188034188, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI71982178, Length=281, Percent_Identity=34.5195729537367, Blast_Score=174, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI17531909, Length=247, Percent_Identity=29.5546558704453, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17562446, Length=263, Percent_Identity=29.6577946768061, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17531913, Length=183, Percent_Identity=27.3224043715847, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI86563383, Length=266, Percent_Identity=26.6917293233083, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI86563381, Length=266, Percent_Identity=26.6917293233083, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21356377, Length=385, Percent_Identity=44.9350649350649, Blast_Score=348, Evalue=5e-96,
Organism=Drosophila melanogaster, GI24646207, Length=386, Percent_Identity=40.9326424870466, Blast_Score=298, Evalue=6e-81,
Organism=Drosophila melanogaster, GI24660351, Length=386, Percent_Identity=39.3782383419689, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24666513, Length=380, Percent_Identity=38.9473684210526, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI21355753, Length=389, Percent_Identity=38.3033419023136, Blast_Score=261, Evalue=5e-70,
Organism=Drosophila melanogaster, GI281363737, Length=391, Percent_Identity=35.0383631713555, Blast_Score=234, Evalue=7e-62,
Organism=Drosophila melanogaster, GI19920834, Length=388, Percent_Identity=30.9278350515464, Blast_Score=178, Evalue=6e-45,
Organism=Drosophila melanogaster, GI24652780, Length=362, Percent_Identity=23.2044198895028, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221473076, Length=313, Percent_Identity=25.2396166134185, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45550141, Length=313, Percent_Identity=25.2396166134185, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281365206, Length=439, Percent_Identity=23.9179954441913, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585193, Length=439, Percent_Identity=23.9179954441913, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585195, Length=439, Percent_Identity=23.9179954441913, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585191, Length=439, Percent_Identity=23.9179954441913, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 42594; Mature: 42594

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFTLDQKHEMARDLFKQFAETEVKPLAQETDETEVFPAETVAKMGKYGFMGIPVPKEYG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHC
GQGCDPLTYVMCVEELSKVCGTTGVIVSAHTSLCIDPIMTFGTEEQKKKYVPDLASGKKI
CCCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCHHHHHCCCCCCCCCEE
GAFGLTEPGAGTDAQGCQTKAVLDGDEWVLNGSKCFITNGKVADVYIIIAITSITEDKRG
CCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCEEEEECCCEEEEEEEEEEEECCCCCCC
RKKKNFSAFIVDKGTPGFSFGTKEKKMGIRGSSTYELIFEDARIPKNALLGKEGRGFPIA
CCCCCCEEEEEECCCCCCCCCCCHHHCCCCCCCEEEEEEECCCCCHHHHCCCCCCCCEEE
MHTLDGGRIGIAAQALGIAEGALERTIEYTKERKQFGRSIAQQQNTQFKLADMATRIDAA
EEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHH
KYLVYAAAMKKAEFAKNPKVSYSVDAAKAKLFAAETAMAVTTECVQLFGGYGYIREYDVE
HHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RMMRDAKITEIYEGTSEVQRMVISGSLLR
HHHHHHHHHHHHCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDFTLDQKHEMARDLFKQFAETEVKPLAQETDETEVFPAETVAKMGKYGFMGIPVPKEYG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHC
GQGCDPLTYVMCVEELSKVCGTTGVIVSAHTSLCIDPIMTFGTEEQKKKYVPDLASGKKI
CCCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCHHHHHCCCCCCCCCEE
GAFGLTEPGAGTDAQGCQTKAVLDGDEWVLNGSKCFITNGKVADVYIIIAITSITEDKRG
CCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCEEEEECCCEEEEEEEEEEEECCCCCCC
RKKKNFSAFIVDKGTPGFSFGTKEKKMGIRGSSTYELIFEDARIPKNALLGKEGRGFPIA
CCCCCCEEEEEECCCCCCCCCCCHHHCCCCCCCEEEEEEECCCCCHHHHCCCCCCCCEEE
MHTLDGGRIGIAAQALGIAEGALERTIEYTKERKQFGRSIAQQQNTQFKLADMATRIDAA
EEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHH
KYLVYAAAMKKAEFAKNPKVSYSVDAAKAKLFAAETAMAVTTECVQLFGGYGYIREYDVE
HHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RMMRDAKITEIYEGTSEVQRMVISGSLLR
HHHHHHHHHHHHCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]