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The map label for this gene is gluP [H]

Identifier: 238922477

GI number: 238922477

Start: 56569

End: 57147

Strand: Direct

Name: gluP [H]

Synonym: EUBREC_0051

Alternate gene names: 238922477

Gene position: 56569-57147 (Clockwise)

Preceding gene: 238922476

Following gene: 238922478

Centisome position: 1.64

GC content: 41.62

Gene sequence:

>579_bases
ATGACAATTGGCATAATAGTGGTAAATATAATAGTTTTTGTGCTGATGAGTATATCAGGCAGCACACTTGATGCACAGTA
TATGGCTGCCCACGGAGCCATGTACCCTGAGTATATAAAGGATGGCCAGTACTGGAGGCTGTTCACTTCGATGTTTATGC
ATTTTGGATTGATGCATATACTTAACAATATGGTGGTTTTAGGTGCTGTCGGTCAGATAGTCGAGAAAGCCATGGGGCAT
GTGAAGCTTCTGATCACATTTCTTGTGTCAGGCATGTGTGGAAGTGTATTGTCATACATCGTTATGCTTTATAATAATGA
TTATGCGGTATCGGCAGGTGCTTCCGGGGCGATATTTGGTCTGGTAGGAGCACTTGTGTGGATAGTTATAGCAAACAGAG
GCTTTTATGAGGGCGTCAGCAGGAAGCAGGCTGTATTTATGGTTATACTGATGATATACTACGGAGTTTCAACGCAGGGA
GTGGACAATTGGGCTCATGGAGGCGGGCTCGTAGGCGGATTTGTTATTTCAATTGTTTTATATCGCAAAAAGAGATATAA
TAAATATAATATCAACTAA

Upstream 100 bases:

>100_bases
AGCTCCTTAAAATTTATAATAAGAAAAAAGTATTTAACAGGAAAATTAAGGAGACCCCACAGATTTGCAGAATATAAAAA
GATTTTATGATAAACCATAT

Downstream 100 bases:

>100_bases
AAATTAATGGTAGGAGAAGCTACATGAAGATAAATATTTATTATGGTGGAAGAGGTTTACTGGACGACCCGACACTGTAT
GTGATAAGCAGGATAGAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MTIGIIVVNIIVFVLMSISGSTLDAQYMAAHGAMYPEYIKDGQYWRLFTSMFMHFGLMHILNNMVVLGAVGQIVEKAMGH
VKLLITFLVSGMCGSVLSYIVMLYNNDYAVSAGASGAIFGLVGALVWIVIANRGFYEGVSRKQAVFMVILMIYYGVSTQG
VDNWAHGGGLVGGFVISIVLYRKKRYNKYNIN

Sequences:

>Translated_192_residues
MTIGIIVVNIIVFVLMSISGSTLDAQYMAAHGAMYPEYIKDGQYWRLFTSMFMHFGLMHILNNMVVLGAVGQIVEKAMGH
VKLLITFLVSGMCGSVLSYIVMLYNNDYAVSAGASGAIFGLVGALVWIVIANRGFYEGVSRKQAVFMVILMIYYGVSTQG
VDNWAHGGGLVGGFVISIVLYRKKRYNKYNIN
>Mature_191_residues
TIGIIVVNIIVFVLMSISGSTLDAQYMAAHGAMYPEYIKDGQYWRLFTSMFMHFGLMHILNNMVVLGAVGQIVEKAMGHV
KLLITFLVSGMCGSVLSYIVMLYNNDYAVSAGASGAIFGLVGALVWIVIANRGFYEGVSRKQAVFMVILMIYYGVSTQGV
DNWAHGGGLVGGFVISIVLYRKKRYNKYNIN

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 21119; Mature: 20988

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
6.8 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIGIIVVNIIVFVLMSISGSTLDAQYMAAHGAMYPEYIKDGQYWRLFTSMFMHFGLMHI
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHH
LNNMVVLGAVGQIVEKAMGHVKLLITFLVSGMCGSVLSYIVMLYNNDYAVSAGASGAIFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHH
LVGALVWIVIANRGFYEGVSRKQAVFMVILMIYYGVSTQGVDNWAHGGGLVGGFVISIVL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHHHHHH
YRKKRYNKYNIN
HHHHHCCCCCCC
>Mature Secondary Structure 
TIGIIVVNIIVFVLMSISGSTLDAQYMAAHGAMYPEYIKDGQYWRLFTSMFMHFGLMHI
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHH
LNNMVVLGAVGQIVEKAMGHVKLLITFLVSGMCGSVLSYIVMLYNNDYAVSAGASGAIFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHH
LVGALVWIVIANRGFYEGVSRKQAVFMVILMIYYGVSTQGVDNWAHGGGLVGGFVISIVL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHHHHHH
YRKKRYNKYNIN
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]