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The map label for this gene is ycbL [H]

Identifier: 238922252

GI number: 238922252

Start: 449769

End: 450392

Strand: Reverse

Name: ycbL [H]

Synonym: EUBELI_20487

Alternate gene names: 238922252

Gene position: 450392-449769 (Counterclockwise)

Preceding gene: 238922253

Following gene: 238922251

Centisome position: 71.86

GC content: 42.15

Gene sequence:

>624_bases
ATGATTAAGATAGAATCAAGAGTATTGGGACCGGTAGCTACTAACTGCTATCTTATAATTAATAAAGATAACAATGAGAG
CATTATTGTTGACCCGGCAGATTCACCGGAGTCTATATATGATATGGTTGTGCGTTCAGCAAGCAAGCCACAGGCAATAC
TTCTTACACATGGACATTTTGACCATATAGGTGCGGCTAATGAGGTGCGTGAGCATTATGGAATTAAGATATATGCATCA
TGTGATGAGGAAAAGCTTCTTGCTTCACCGGCAAGAAACCTGTCAAATGCATACGGCATGAGTCTTAGGGTTACAGCAGA
TGTACTTCATAATGATGGGGATATTCTTGAACTTGCAGGACTTAAGATAAAGGCAATCCATACACCGGGACATACAGCAG
GCGGAACATGCTACTATATCGAATCGGACAAGACGCTTATGTCAGGTGATACACTTTTTGCTGGTTCAGTTGGGAGAACA
GATTACCCTACAGCAAGCTCTGCTGCAATGATGGAGTCACTTCATGACAAGCTCTGCAAGCTCCCTGACGATACAGATGT
ATATCCTGGACATGGAGAGTTCACAACGATTGGATATGAAAAGCAGAACAATCCGTTTATGTGA

Upstream 100 bases:

>100_bases
CACGGCAAGGAAGAACTTAACAGAATTATAGATAAATTAAGAAAGATAGACGGAGTTACTGATATAACAAGAACTGCCGG
CTAAGAAAGGTTTGCAGATT

Downstream 100 bases:

>100_bases
TGTCCGCAAGCGAAAAGGAAGCAACGCGAAGCGTTATTTACTTTTCGCGGGACATCAACGAGCAAACGCCTGCGAAGCAG
GCTGGAAAGCACGATAGTGC

Product: hydroxyacylglutathione hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MIKIESRVLGPVATNCYLIINKDNNESIIVDPADSPESIYDMVVRSASKPQAILLTHGHFDHIGAANEVREHYGIKIYAS
CDEEKLLASPARNLSNAYGMSLRVTADVLHNDGDILELAGLKIKAIHTPGHTAGGTCYYIESDKTLMSGDTLFAGSVGRT
DYPTASSAAMMESLHDKLCKLPDDTDVYPGHGEFTTIGYEKQNNPFM

Sequences:

>Translated_207_residues
MIKIESRVLGPVATNCYLIINKDNNESIIVDPADSPESIYDMVVRSASKPQAILLTHGHFDHIGAANEVREHYGIKIYAS
CDEEKLLASPARNLSNAYGMSLRVTADVLHNDGDILELAGLKIKAIHTPGHTAGGTCYYIESDKTLMSGDTLFAGSVGRT
DYPTASSAAMMESLHDKLCKLPDDTDVYPGHGEFTTIGYEKQNNPFM
>Mature_207_residues
MIKIESRVLGPVATNCYLIINKDNNESIIVDPADSPESIYDMVVRSASKPQAILLTHGHFDHIGAANEVREHYGIKIYAS
CDEEKLLASPARNLSNAYGMSLRVTADVLHNDGDILELAGLKIKAIHTPGHTAGGTCYYIESDKTLMSGDTLFAGSVGRT
DYPTASSAAMMESLHDKLCKLPDDTDVYPGHGEFTTIGYEKQNNPFM

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI94538322, Length=185, Percent_Identity=29.7297297297297, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI94538320, Length=185, Percent_Identity=29.7297297297297, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI21703352, Length=181, Percent_Identity=30.939226519337, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI116642887, Length=181, Percent_Identity=31.4917127071823, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI41327741, Length=211, Percent_Identity=25.1184834123223, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787158, Length=197, Percent_Identity=36.0406091370558, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1786406, Length=182, Percent_Identity=34.6153846153846, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538952, Length=198, Percent_Identity=30.8080808080808, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17536925, Length=153, Percent_Identity=31.3725490196078, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6320478, Length=190, Percent_Identity=25.7894736842105, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356335, Length=200, Percent_Identity=32, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24667711, Length=200, Percent_Identity=32, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24667703, Length=200, Percent_Identity=32, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI221330176, Length=201, Percent_Identity=28.3582089552239, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 22536; Mature: 22536

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKIESRVLGPVATNCYLIINKDNNESIIVDPADSPESIYDMVVRSASKPQAILLTHGHF
CEEECCEECCCCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCC
DHIGAANEVREHYGIKIYASCDEEKLLASPARNLSNAYGMSLRVTADVLHNDGDILELAG
CCCCCHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCEEEECC
LKIKAIHTPGHTAGGTCYYIESDKTLMSGDTLFAGSVGRTDYPTASSAAMMESLHDKLCK
EEEEEEECCCCCCCCEEEEEECCCEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHC
LPDDTDVYPGHGEFTTIGYEKQNNPFM
CCCCCCCCCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MIKIESRVLGPVATNCYLIINKDNNESIIVDPADSPESIYDMVVRSASKPQAILLTHGHF
CEEECCEECCCCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCC
DHIGAANEVREHYGIKIYASCDEEKLLASPARNLSNAYGMSLRVTADVLHNDGDILELAG
CCCCCHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCEEEECC
LKIKAIHTPGHTAGGTCYYIESDKTLMSGDTLFAGSVGRTDYPTASSAAMMESLHDKLCK
EEEEEEECCCCCCCCEEEEEECCCEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHC
LPDDTDVYPGHGEFTTIGYEKQNNPFM
CCCCCCCCCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]