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The map label for this gene is cobU [H]

Identifier: 238921945

GI number: 238921945

Start: 142591

End: 143130

Strand: Reverse

Name: cobU [H]

Synonym: EUBELI_20179

Alternate gene names: 238921945

Gene position: 143130-142591 (Counterclockwise)

Preceding gene: 238921946

Following gene: 238921944

Centisome position: 22.84

GC content: 40.74

Gene sequence:

>540_bases
ATGTTGATTATAATTACAGGGGTAAGCGGCAGCGGCAAGTCAGAATATGCTGAACAGATATGCTGCCGGCTTGCCGGAGA
TAATAAAAAATATTATGTGGCAACCATGCAGCCTTTCGGAGAGGAAGGCAGAATAAGAATTGAAAAGCATAAAAGGCAGC
GTGAGGGAAAAGGCTTTGAAACGATAGAGCAGTATCAGAATATAGGCAGTGCATTGGATTGCTGTGATAAAGAAGAAAGA
CCGGTGGTATTAGTTGAATGCATGTCTAACCTTCTTGCCAACGAATGTTTTGGAGAAGCCGGAAAACCAGATGATATATT
TGATGGCTGTATGAAACTGTATTCAGGATGCAGGCATCTTGTTATTGTAACAAATGAAGTATTTTCAGACGGATGTGAAT
ATGATGCCGGTACAACTGATTATATCAGGCGGCTTGGGGAGATTAATGTGAGGCTTTCCAGAGCAGCAGATGCAGTTGTA
GAAGTTGTATATTCAATTCCTGTATTTTTAAAGGGGGATATTGGCGATGTCGATAATTAA

Upstream 100 bases:

>100_bases
CAGTTATGATGTTTCCGCTTTTTGACATGGCTTTGCAGGTGTACAGGGAAAATACTACATTTGACGATATACAGATAGCT
GCATATGAGGATTATGGAAA

Downstream 100 bases:

>100_bases
ATCACTGGTGATTGCATTTTCAATGTATTCCAAAATACCAATGCCACATCTTGAATTAGATGAAAAAGACATGAAATATG
TAATGGGATTCTTTCCGCTG

Product: adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MLIIITGVSGSGKSEYAEQICCRLAGDNKKYYVATMQPFGEEGRIRIEKHKRQREGKGFETIEQYQNIGSALDCCDKEER
PVVLVECMSNLLANECFGEAGKPDDIFDGCMKLYSGCRHLVIVTNEVFSDGCEYDAGTTDYIRRLGEINVRLSRAADAVV
EVVYSIPVFLKGDIGDVDN

Sequences:

>Translated_179_residues
MLIIITGVSGSGKSEYAEQICCRLAGDNKKYYVATMQPFGEEGRIRIEKHKRQREGKGFETIEQYQNIGSALDCCDKEER
PVVLVECMSNLLANECFGEAGKPDDIFDGCMKLYSGCRHLVIVTNEVFSDGCEYDAGTTDYIRRLGEINVRLSRAADAVV
EVVYSIPVFLKGDIGDVDN
>Mature_179_residues
MLIIITGVSGSGKSEYAEQICCRLAGDNKKYYVATMQPFGEEGRIRIEKHKRQREGKGFETIEQYQNIGSALDCCDKEER
PVVLVECMSNLLANECFGEAGKPDDIFDGCMKLYSGCRHLVIVTNEVFSDGCEYDAGTTDYIRRLGEINVRLSRAADAVV
EVVYSIPVFLKGDIGDVDN

Specific function: ATP-dependent phosphorylation of adenosylcobinamide and adds GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=188, Percent_Identity=31.9148936170213, Blast_Score=67, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 19897; Mature: 19897

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIIITGVSGSGKSEYAEQICCRLAGDNKKYYVATMQPFGEEGRIRIEKHKRQREGKGFE
CEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEHHHHHHHHCCCCHH
TIEQYQNIGSALDCCDKEERPVVLVECMSNLLANECFGEAGKPDDIFDGCMKLYSGCRHL
HHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEE
VIVTNEVFSDGCEYDAGTTDYIRRLGEINVRLSRAADAVVEVVYSIPVFLKGDIGDVDN
EEEECHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEECCCCCCCC
>Mature Secondary Structure
MLIIITGVSGSGKSEYAEQICCRLAGDNKKYYVATMQPFGEEGRIRIEKHKRQREGKGFE
CEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEHHHHHHHHCCCCHH
TIEQYQNIGSALDCCDKEERPVVLVECMSNLLANECFGEAGKPDDIFDGCMKLYSGCRHL
HHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEE
VIVTNEVFSDGCEYDAGTTDYIRRLGEINVRLSRAADAVVEVVYSIPVFLKGDIGDVDN
EEEECHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]