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The map label for this gene is rbsK [H]

Identifier: 238921723

GI number: 238921723

Start: 3768436

End: 3769365

Strand: Reverse

Name: rbsK [H]

Synonym: NT01EI_3892

Alternate gene names: 238921723

Gene position: 3769365-3768436 (Counterclockwise)

Preceding gene: 238921724

Following gene: 238921722

Centisome position: 98.87

GC content: 59.25

Gene sequence:

>930_bases
ATGCAAACAGGCAAACTGGTCGTATTAGGCAGTATCAATGCCGATCACATTCTCAAGGTCGAACATTTTCCCCGCCCCGG
CGAAACCTTAACCGGACAGGGATATCAGGTGGCATTCGGCGGTAAAGGGGCCAATCAGGCCGTTGCCGCCGGGCGCAGCG
GTGCGGATATTGCCTTTATTGCCTGTGTTGGCGCCGATGATATCGGCGAACGGATCCGAACCCAGTTGGCCGGTGATGGG
ATCGATATACACGCCGTGGAGCGCGTCGATGGCGAAAGCACCGGCGTGGCACTGATTTTTGTCAATCAGGATGGGGAGAA
TGTCATTGGCATCAACGCCGGTGCTAATCATGCGCTGACGCCGCAGTATCTATCTCACCACCGGACGCTGGTGGTGCAGG
CAGATGCGCTGCTGATGCAGCTGGAGTCACCGTTGGAGACCGTTGAAGCCGCCGCGGTGCTGGCCCGAGAGCATCAGACC
AAGGTAATTTTGAATCCCGCACCGGCGCGGACGCTGCCGGATTCTCTGCTGCGGCTGGTGGATGTCATCACTCCCAATGA
GACCGAGGCTGAGCATCTGACCGGTATTCGGGTCCACAGCGATGAGAGTGCTCGCCAAGCCGCCGCTGTATTGCACGGTA
AAGGCATCGAAACCGTGATGATAACGCTTGGTCGCCGCGGCGTTTGGGTCAGCCAGGAGGGGTATGGTGAAGTGATCCCG
GGATTTAGGGTTAACGCTGTCGATACCATTGCTGCCGGGGATACCTTTAACGGTGCGTTGCTAACCGCTCTGCTGGAGGG
GAATACCCTGCCTGCCGCCGTGCGCTTTGCCCATGCTGCCGCGGCGATCGCCGTGACGCGTGAGGGCGCGCAGTCCTCTG
TCCCTTGGCGCCGTGAGATCGATGCCTTCCTACAGACGCATCAGGAGTAA

Upstream 100 bases:

>100_bases
GGTTGAGCTGAAGCTGGTCACCAAGTAACGTACCGGGAGACCCTCCGGGCAACGCCGCCGCTGGGATACCGGCGGCGGTA
GATAAGTAGGAATACAGAAT

Downstream 100 bases:

>100_bases
TCATACGTGGCAACAATGAAGGACGTCGCCCGTCTCGCAGGCGTCTCCACCTCGACTGTATCCCATGTCATCAATAACAA
TCGCTTCGTCAGCGACAGTG

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MQTGKLVVLGSINADHILKVEHFPRPGETLTGQGYQVAFGGKGANQAVAAGRSGADIAFIACVGADDIGERIRTQLAGDG
IDIHAVERVDGESTGVALIFVNQDGENVIGINAGANHALTPQYLSHHRTLVVQADALLMQLESPLETVEAAAVLAREHQT
KVILNPAPARTLPDSLLRLVDVITPNETEAEHLTGIRVHSDESARQAAAVLHGKGIETVMITLGRRGVWVSQEGYGEVIP
GFRVNAVDTIAAGDTFNGALLTALLEGNTLPAAVRFAHAAAAIAVTREGAQSSVPWRREIDAFLQTHQE

Sequences:

>Translated_309_residues
MQTGKLVVLGSINADHILKVEHFPRPGETLTGQGYQVAFGGKGANQAVAAGRSGADIAFIACVGADDIGERIRTQLAGDG
IDIHAVERVDGESTGVALIFVNQDGENVIGINAGANHALTPQYLSHHRTLVVQADALLMQLESPLETVEAAAVLAREHQT
KVILNPAPARTLPDSLLRLVDVITPNETEAEHLTGIRVHSDESARQAAAVLHGKGIETVMITLGRRGVWVSQEGYGEVIP
GFRVNAVDTIAAGDTFNGALLTALLEGNTLPAAVRFAHAAAAIAVTREGAQSSVPWRREIDAFLQTHQE
>Mature_309_residues
MQTGKLVVLGSINADHILKVEHFPRPGETLTGQGYQVAFGGKGANQAVAAGRSGADIAFIACVGADDIGERIRTQLAGDG
IDIHAVERVDGESTGVALIFVNQDGENVIGINAGANHALTPQYLSHHRTLVVQADALLMQLESPLETVEAAAVLAREHQT
KVILNPAPARTLPDSLLRLVDVITPNETEAEHLTGIRVHSDESARQAAAVLHGKGIETVMITLGRRGVWVSQEGYGEVIP
GFRVNAVDTIAAGDTFNGALLTALLEGNTLPAAVRFAHAAAAIAVTREGAQSSVPWRREIDAFLQTHQE

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=297, Percent_Identity=37.037037037037, Blast_Score=162, Evalue=3e-40,
Organism=Escherichia coli, GI1790193, Length=305, Percent_Identity=71.4754098360656, Blast_Score=403, Evalue=1e-114,
Organism=Escherichia coli, GI87081971, Length=303, Percent_Identity=27.7227722772277, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082343, Length=300, Percent_Identity=29, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788491, Length=256, Percent_Identity=26.171875, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788484, Length=280, Percent_Identity=27.5, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788417, Length=309, Percent_Identity=26.537216828479, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=308, Percent_Identity=37.3376623376623, Blast_Score=184, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6319884, Length=334, Percent_Identity=29.3413173652695, Blast_Score=125, Evalue=6e-30,
Organism=Drosophila melanogaster, GI20128807, Length=307, Percent_Identity=37.4592833876222, Blast_Score=144, Evalue=9e-35,
Organism=Drosophila melanogaster, GI24583886, Length=307, Percent_Identity=30.9446254071661, Blast_Score=131, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32619; Mature: 32619

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTGKLVVLGSINADHILKVEHFPRPGETLTGQGYQVAFGGKGANQAVAAGRSGADIAFI
CCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCHHHHCCCCCCCEEEE
ACVGADDIGERIRTQLAGDGIDIHAVERVDGESTGVALIFVNQDGENVIGINAGANHALT
EEECCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEEEECCCCCCCC
PQYLSHHRTLVVQADALLMQLESPLETVEAAAVLAREHQTKVILNPAPARTLPDSLLRLV
HHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHH
DVITPNETEAEHLTGIRVHSDESARQAAAVLHGKGIETVMITLGRRGVWVSQEGYGEVIP
HHCCCCCCCHHHHEEEEEECCCHHHHHHHHHCCCCCEEEEEEECCCCEEECCCCCCCCCC
GFRVNAVDTIAAGDTFNGALLTALLEGNTLPAAVRFAHAAAAIAVTREGAQSSVPWRREI
CCEECCEEEEECCCCCCHHHEEEECCCCCCHHHHHHHHHHEEEEEECCCCCCCCCHHHHH
DAFLQTHQE
HHHHHHCCC
>Mature Secondary Structure
MQTGKLVVLGSINADHILKVEHFPRPGETLTGQGYQVAFGGKGANQAVAAGRSGADIAFI
CCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCHHHHCCCCCCCEEEE
ACVGADDIGERIRTQLAGDGIDIHAVERVDGESTGVALIFVNQDGENVIGINAGANHALT
EEECCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEEEECCCCCCCC
PQYLSHHRTLVVQADALLMQLESPLETVEAAAVLAREHQTKVILNPAPARTLPDSLLRLV
HHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHH
DVITPNETEAEHLTGIRVHSDESARQAAAVLHGKGIETVMITLGRRGVWVSQEGYGEVIP
HHCCCCCCCHHHHEEEEEECCCHHHHHHHHHCCCCCEEEEEEECCCCEEECCCCCCCCCC
GFRVNAVDTIAAGDTFNGALLTALLEGNTLPAAVRFAHAAAAIAVTREGAQSSVPWRREI
CCEECCEEEEECCCCCCHHHEEEECCCCCCHHHHHHHHHHEEEEEECCCCCCCCCHHHHH
DAFLQTHQE
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]