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The map label for this gene is dppC [H]

Identifier: 238921610

GI number: 238921610

Start: 3647383

End: 3648303

Strand: Reverse

Name: dppC [H]

Synonym: NT01EI_3763

Alternate gene names: 238921610

Gene position: 3648303-3647383 (Counterclockwise)

Preceding gene: 238921611

Following gene: 238921609

Centisome position: 95.7

GC content: 65.15

Gene sequence:

>921_bases
ATGTCTGAACCAACAACGGCCGCGACGGCGACCACCCCATCCGGTGTCCCGGCCCCGCGGCCGATGACGCCGCTGCAGGA
GTTCTGGCACTATTTTCGCCGCAATAAAGGCGCCGTCGCAGGGCTTATCTACGTAGCGATCGTGGTGGTGGTGGCGCTGG
GGGCCAATATCATTGCGCCGCACCTGCCGCAGGAGCAGTTCCGCGATGCGTTGCTGCGTCCGCCGGTCTGGGAGGCCGAC
GGCAGCTGGCGCTTTATTCTGGGTACCGATGACGTGGGGCGCGACGTGCTGTCGCGGTTGATTTACGGCGCCCGTCTGTC
GCTGCTGGTGGGCTGCCTGGTGGTTGCGCTGTCGCTGATCCTCGGGGTGGTGCTGGGGCTGCTGGCGGGCTACTTCGGCG
GCGCGGTGGATGCGCTGGTCATGCGGGTGGTCGATATCATGCTGGCGCTGCCGAGTCTGCTGCTGGCGCTGGTGCTGGTG
GCCATGTTCGGCCCCTCTATCGTCAATGCGTCGCTGGCGCTGACCTTTGTGGCGCTGCCACACTATGTCCGCCTTACGCG
CGCCGCGATATTGGCGGAGGTGCATCGCGACTACGTGACCGCCTCCGGGGTGGCTGGCGCCGGTGCGCTGCGCCAGATGT
TCGTCAATATCCTGCCCAACTGCCTGGCGCCGCTGATCGTGCAGGCGTCGCTGGGTTTTTCTAATGCGATCCTCGATATG
GCCGCGCTGGGTTTCCTGGGAATGGGCGCCCAGCCGCCGACGCCGGAGTGGGGCACCATGCTGTCCGATGTGCTGCAGTT
TGCCCAGAGCGCCTGGTGGGTGGTGACTTTTCCCGGACTGGCCATTCTGTTGACGGTACTGGCGTTTAATCTGATGGGCG
ACGGCCTGCGCGATGCGCTGGATCCGAAGTTGAAGCAGTAA

Upstream 100 bases:

>100_bases
CTGCTGGTCGCCAGTATGATCATTCTGGTTAACCTGCTGGTCGACGTGCTGTACGGCATCGTTAACCCGCGTATCCGCCA
TAAACACTAGGAGGCCGCTG

Downstream 100 bases:

>100_bases
GGAGAGGGACATGGCATTACTGGATGTAGATCAGCTATCGGTGCATTTTGGTAACGATAGTGCCCCTTTCCGTGCGGTTG
ACCGCATCAGCTACCAGGTT

Product: dipeptide transporter

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSEPTTAATATTPSGVPAPRPMTPLQEFWHYFRRNKGAVAGLIYVAIVVVVALGANIIAPHLPQEQFRDALLRPPVWEAD
GSWRFILGTDDVGRDVLSRLIYGARLSLLVGCLVVALSLILGVVLGLLAGYFGGAVDALVMRVVDIMLALPSLLLALVLV
AMFGPSIVNASLALTFVALPHYVRLTRAAILAEVHRDYVTASGVAGAGALRQMFVNILPNCLAPLIVQASLGFSNAILDM
AALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ

Sequences:

>Translated_306_residues
MSEPTTAATATTPSGVPAPRPMTPLQEFWHYFRRNKGAVAGLIYVAIVVVVALGANIIAPHLPQEQFRDALLRPPVWEAD
GSWRFILGTDDVGRDVLSRLIYGARLSLLVGCLVVALSLILGVVLGLLAGYFGGAVDALVMRVVDIMLALPSLLLALVLV
AMFGPSIVNASLALTFVALPHYVRLTRAAILAEVHRDYVTASGVAGAGALRQMFVNILPNCLAPLIVQASLGFSNAILDM
AALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ
>Mature_305_residues
SEPTTAATATTPSGVPAPRPMTPLQEFWHYFRRNKGAVAGLIYVAIVVVVALGANIIAPHLPQEQFRDALLRPPVWEADG
SWRFILGTDDVGRDVLSRLIYGARLSLLVGCLVVALSLILGVVLGLLAGYFGGAVDALVMRVVDIMLALPSLLLALVLVA
MFGPSIVNASLALTFVALPHYVRLTRAAILAEVHRDYVTASGVAGAGALRQMFVNILPNCLAPLIVQASLGFSNAILDMA
ALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=299, Percent_Identity=82.943143812709, Blast_Score=426, Evalue=1e-121,
Organism=Escherichia coli, GI1787054, Length=284, Percent_Identity=40.8450704225352, Blast_Score=210, Evalue=8e-56,
Organism=Escherichia coli, GI1787760, Length=262, Percent_Identity=45.4198473282443, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1787549, Length=281, Percent_Identity=40.9252669039146, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1789889, Length=219, Percent_Identity=39.2694063926941, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1787498, Length=278, Percent_Identity=34.8920863309352, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788505, Length=218, Percent_Identity=31.1926605504587, Blast_Score=101, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32533; Mature: 32402

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPTTAATATTPSGVPAPRPMTPLQEFWHYFRRNKGAVAGLIYVAIVVVVALGANIIAP
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHCC
HLPQEQFRDALLRPPVWEADGSWRFILGTDDVGRDVLSRLIYGARLSLLVGCLVVALSLI
CCCHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVVLGLLAGYFGGAVDALVMRVVDIMLALPSLLLALVLVAMFGPSIVNASLALTFVALP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
HYVRLTRAAILAEVHRDYVTASGVAGAGALRQMFVNILPNCLAPLIVQASLGFSNAILDM
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDAL
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCHHHHHC
DPKLKQ
CCCCCC
>Mature Secondary Structure 
SEPTTAATATTPSGVPAPRPMTPLQEFWHYFRRNKGAVAGLIYVAIVVVVALGANIIAP
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHCC
HLPQEQFRDALLRPPVWEADGSWRFILGTDDVGRDVLSRLIYGARLSLLVGCLVVALSLI
CCCHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVVLGLLAGYFGGAVDALVMRVVDIMLALPSLLLALVLVAMFGPSIVNASLALTFVALP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
HYVRLTRAAILAEVHRDYVTASGVAGAGALRQMFVNILPNCLAPLIVQASLGFSNAILDM
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDAL
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCHHHHHC
DPKLKQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]