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The map label for this gene is dppB [H]

Identifier: 238921611

GI number: 238921611

Start: 3648314

End: 3649333

Strand: Reverse

Name: dppB [H]

Synonym: NT01EI_3764

Alternate gene names: 238921611

Gene position: 3649333-3648314 (Counterclockwise)

Preceding gene: 238921612

Following gene: 238921610

Centisome position: 95.72

GC content: 59.31

Gene sequence:

>1020_bases
ATGCTGCAGTTTATTCTCCGGCGTTTGGGGCTGGTCACCCCAACGTTTATTGGTATTACGTTGCTGACATTCGCGTTTGT
TCACATGATCCCCGGCGATCCGGTGATGATCATGGCGGGCGAGCGAGGGATCTCCGCGGAGCGTCATGCTCAAATCATGG
CTGAGATGGGGCTGGATAAGCCGCTATACCAACAATACTTCATCTATATCGACGACGTGCTGCACGGCAACCTCGGTCAG
TCCCTGAAAAGCCGGACCCCGGTATGGCAGGAGTTTGTGCCGCGCTTTCAGGCGACGCTGGAGCTGGGGATCTGCGCCAT
GCTGTTCGCGGTACTGCTGGGGATCCCTATCGGAGTTTTGGCTGCCGTCAAGCGGGGATCCGTCTTTGATCATACGGCGG
TCGGCGTGGCGCTGACCGGCTACTCCATGCCGATTTTCTGGTGGGGCATGATGCTGATTATGCTGGTCTCGGTCAATCTG
GATTTGACGCCGGTTTCCGGGCGTATCAGCGACACGGTATTTCTGGATGATAGCCACCCGTTGACCGGCTTTATGCTGAT
CGACACCCTGCTGTGGGGAGAGCCGGGGGACTTTAAGGATGCGGTAATGCACCTGATCCTGCCCTCTATTGTTCTGGGTA
CCATTCCGCTGGCGGTGATCGTGCGTATGACCCGTTCGGCGATGCTGGAGGTGCTGAGCGAGGACTATATCCGCACCGCC
CGTGCCAAGGGGCTGAGCCGCCTGCGGGTGATCGTGGTGCATGCCCTGCGCAATGCGCTGCTGCCGGTGGTGACGGTGAT
CGGCCTGCAGGTCGGTACGCTGTTGGCCGGGGCTATCCTGACGGAGACTATCTTCTCTTGGCCGGGGCTGGGGCGCTGGC
TGATCGATGGCCTGCAGCGCCGCGACTATCCGGTGGTGCAGGGTGGTGTTCTGCTGGTCGCCAGTATGATCATTCTGGTT
AACCTGCTGGTCGACGTGCTGTACGGCATCGTTAACCCGCGTATCCGCCATAAACACTAG

Upstream 100 bases:

>100_bases
GCCGTGAGGTCAGGCGGTATCCGGGGTCAGGCGCAGCGCACTCTTGCGCGGCGAAGCGGGCCGACGGGTGAGTGCCGGCC
AACTACAGAGAGTTCGGGCT

Downstream 100 bases:

>100_bases
GAGGCCGCTGATGTCTGAACCAACAACGGCCGCGACGGCGACCACCCCATCCGGTGTCCCGGCCCCGCGGCCGATGACGC
CGCTGCAGGAGTTCTGGCAC

Product: dipeptide transporter permease DppB

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MLQFILRRLGLVTPTFIGITLLTFAFVHMIPGDPVMIMAGERGISAERHAQIMAEMGLDKPLYQQYFIYIDDVLHGNLGQ
SLKSRTPVWQEFVPRFQATLELGICAMLFAVLLGIPIGVLAAVKRGSVFDHTAVGVALTGYSMPIFWWGMMLIMLVSVNL
DLTPVSGRISDTVFLDDSHPLTGFMLIDTLLWGEPGDFKDAVMHLILPSIVLGTIPLAVIVRMTRSAMLEVLSEDYIRTA
RAKGLSRLRVIVVHALRNALLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDGLQRRDYPVVQGGVLLVASMIILV
NLLVDVLYGIVNPRIRHKH

Sequences:

>Translated_339_residues
MLQFILRRLGLVTPTFIGITLLTFAFVHMIPGDPVMIMAGERGISAERHAQIMAEMGLDKPLYQQYFIYIDDVLHGNLGQ
SLKSRTPVWQEFVPRFQATLELGICAMLFAVLLGIPIGVLAAVKRGSVFDHTAVGVALTGYSMPIFWWGMMLIMLVSVNL
DLTPVSGRISDTVFLDDSHPLTGFMLIDTLLWGEPGDFKDAVMHLILPSIVLGTIPLAVIVRMTRSAMLEVLSEDYIRTA
RAKGLSRLRVIVVHALRNALLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDGLQRRDYPVVQGGVLLVASMIILV
NLLVDVLYGIVNPRIRHKH
>Mature_339_residues
MLQFILRRLGLVTPTFIGITLLTFAFVHMIPGDPVMIMAGERGISAERHAQIMAEMGLDKPLYQQYFIYIDDVLHGNLGQ
SLKSRTPVWQEFVPRFQATLELGICAMLFAVLLGIPIGVLAAVKRGSVFDHTAVGVALTGYSMPIFWWGMMLIMLVSVNL
DLTPVSGRISDTVFLDDSHPLTGFMLIDTLLWGEPGDFKDAVMHLILPSIVLGTIPLAVIVRMTRSAMLEVLSEDYIRTA
RAKGLSRLRVIVVHALRNALLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDGLQRRDYPVVQGGVLLVASMIILV
NLLVDVLYGIVNPRIRHKH

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=85.2507374631269, Blast_Score=589, Evalue=1e-170,
Organism=Escherichia coli, GI1787053, Length=338, Percent_Identity=42.3076923076923, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1787761, Length=318, Percent_Identity=46.2264150943396, Blast_Score=244, Evalue=6e-66,
Organism=Escherichia coli, GI1787550, Length=283, Percent_Identity=37.1024734982332, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1787497, Length=338, Percent_Identity=34.9112426035503, Blast_Score=197, Evalue=9e-52,
Organism=Escherichia coli, GI1789888, Length=341, Percent_Identity=31.3782991202346, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1788504, Length=380, Percent_Identity=28.1578947368421, Blast_Score=135, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37411; Mature: 37411

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQFILRRLGLVTPTFIGITLLTFAFVHMIPGDPVMIMAGERGISAERHAQIMAEMGLDK
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCC
PLYQQYFIYIDDVLHGNLGQSLKSRTPVWQEFVPRFQATLELGICAMLFAVLLGIPIGVL
HHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVKRGSVFDHTAVGVALTGYSMPIFWWGMMLIMLVSVNLDLTPVSGRISDTVFLDDSHP
HHHHCCCCCCHHHHHHEEECCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEECCCCC
LTGFMLIDTLLWGEPGDFKDAVMHLILPSIVLGTIPLAVIVRMTRSAMLEVLSEDYIRTA
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAKGLSRLRVIVVHALRNALLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDGLQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
RDYPVVQGGVLLVASMIILVNLLVDVLYGIVNPRIRHKH
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLQFILRRLGLVTPTFIGITLLTFAFVHMIPGDPVMIMAGERGISAERHAQIMAEMGLDK
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCC
PLYQQYFIYIDDVLHGNLGQSLKSRTPVWQEFVPRFQATLELGICAMLFAVLLGIPIGVL
HHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVKRGSVFDHTAVGVALTGYSMPIFWWGMMLIMLVSVNLDLTPVSGRISDTVFLDDSHP
HHHHCCCCCCHHHHHHEEECCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEECCCCC
LTGFMLIDTLLWGEPGDFKDAVMHLILPSIVLGTIPLAVIVRMTRSAMLEVLSEDYIRTA
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAKGLSRLRVIVVHALRNALLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDGLQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
RDYPVVQGGVLLVASMIILVNLLVDVLYGIVNPRIRHKH
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]