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The map label for this gene is era [H]

Identifier: 238920904

GI number: 238920904

Start: 2920408

End: 2921313

Strand: Reverse

Name: era [H]

Synonym: NT01EI_3031

Alternate gene names: 238920904

Gene position: 2921313-2920408 (Counterclockwise)

Preceding gene: 238920905

Following gene: 238920903

Centisome position: 76.63

GC content: 56.07

Gene sequence:

>906_bases
ATGAGCGAAGAAAAAACCTACTGCGGCTTTATTGCCATCGTTGGCCGTCCCAATGTCGGTAAGTCAACGTTACTGAACCA
GTTGCTGGGGCAAAAAATTTCCATCACCTCGCGTAAGCCGCAGACCACCCGTCACCGCATTATGGGTATCCATACGGAAG
GTCCGTACCAGGCTATCTATGTTGATACCCCGGGGCTGCACATTGAGGAGAAACGGGCCATTAACCGCCTGATGAACCGT
GCGGCCAGCAGCTCCATCGGCGATGTCGAACTGGTGATTTTTGTGGTGGAAGGCACCCACTGGACGCCGGATGATGAGAT
GGTGCTCAACAAGCTGCGCGACCTGAAGTGCCCGGTGATCCTGGCGATCAACAAGGTAGACAACGTGGTCGACAAGACTG
CACTGCTGCCGCACATTCAGTTCTTGAGCCAGCAGATGAACTTTTTGGACGTGGTGCCGATCTCGGCAGAGAAGGGCACC
AACGTGGACGCTATTGCCCGCATCGTGCGCCAGCGCCTGCCGCAGGCGGAGCACCATTTCCCTGAGGAGTACATCACCGA
TCGCTCCCAGCGTTTTATGGCCTCTGAGATCATCCGTGAAAAGCTGATGCGCTTCCTCGGCGAGGAGCTGCCCTACTCGG
TCACCGTAGAGATCGAACGCTTTGCGCCAAACGAGCGCGGTGGCTATGACATCCACGGTCTGATCCTGGTGGAGCGCGAT
GGCCAGAAGAAGATGGTCATCGGCAACAAAGGTAGCAAGATCAAAACCATTGGTATCGAAGCGCGCCAGGACATGGAGGC
GATGTTTGATGCCAAGGTGCATCTTGAGCTGTGGGTTAAGGTGAAATCCGGCTGGGCGGACGATGAACGTGCGCTGCGTA
GCCTGGGTTACGTCGACGATCTGTAA

Upstream 100 bases:

>100_bases
AGGTCAGCGGGCTGTCCGCGCCGGTAGTTGGTGTCGGCTCCAGCCGGCGCAAGGCCGAGCAGGCCGCCGCCGAGCAGGCG
TTAAAACAGTTGGAGCTTGA

Downstream 100 bases:

>100_bases
ACCGTACCATGGACGGCTGGCAACGCGCCTTCGTGCTGCACGCACGGCCCTACAGTGAAACCAGCCTGATGCTGGACACG
TTCACCGAGGGGCATGGCCG

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSEEKTYCGFIAIVGRPNVGKSTLLNQLLGQKISITSRKPQTTRHRIMGIHTEGPYQAIYVDTPGLHIEEKRAINRLMNR
AASSSIGDVELVIFVVEGTHWTPDDEMVLNKLRDLKCPVILAINKVDNVVDKTALLPHIQFLSQQMNFLDVVPISAEKGT
NVDAIARIVRQRLPQAEHHFPEEYITDRSQRFMASEIIREKLMRFLGEELPYSVTVEIERFAPNERGGYDIHGLILVERD
GQKKMVIGNKGSKIKTIGIEARQDMEAMFDAKVHLELWVKVKSGWADDERALRSLGYVDDL

Sequences:

>Translated_301_residues
MSEEKTYCGFIAIVGRPNVGKSTLLNQLLGQKISITSRKPQTTRHRIMGIHTEGPYQAIYVDTPGLHIEEKRAINRLMNR
AASSSIGDVELVIFVVEGTHWTPDDEMVLNKLRDLKCPVILAINKVDNVVDKTALLPHIQFLSQQMNFLDVVPISAEKGT
NVDAIARIVRQRLPQAEHHFPEEYITDRSQRFMASEIIREKLMRFLGEELPYSVTVEIERFAPNERGGYDIHGLILVERD
GQKKMVIGNKGSKIKTIGIEARQDMEAMFDAKVHLELWVKVKSGWADDERALRSLGYVDDL
>Mature_300_residues
SEEKTYCGFIAIVGRPNVGKSTLLNQLLGQKISITSRKPQTTRHRIMGIHTEGPYQAIYVDTPGLHIEEKRAINRLMNRA
ASSSIGDVELVIFVVEGTHWTPDDEMVLNKLRDLKCPVILAINKVDNVVDKTALLPHIQFLSQQMNFLDVVPISAEKGTN
VDAIARIVRQRLPQAEHHFPEEYITDRSQRFMASEIIREKLMRFLGEELPYSVTVEIERFAPNERGGYDIHGLILVERDG
QKKMVIGNKGSKIKTIGIEARQDMEAMFDAKVHLELWVKVKSGWADDERALRSLGYVDDL

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=321, Percent_Identity=28.0373831775701, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1788919, Length=301, Percent_Identity=86.046511627907, Blast_Score=541, Evalue=1e-155,
Organism=Escherichia coli, GI87082120, Length=181, Percent_Identity=29.8342541436464, Blast_Score=66, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646434, Length=302, Percent_Identity=24.8344370860927, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34159; Mature: 34028

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEKTYCGFIAIVGRPNVGKSTLLNQLLGQKISITSRKPQTTRHRIMGIHTEGPYQAIY
CCCCCCEEEEEEEECCCCCCHHHHHHHHHCCEEEECCCCCCCCHHHEEEEECCCCEEEEE
VDTPGLHIEEKRAINRLMNRAASSSIGDVELVIFVVEGTHWTPDDEMVLNKLRDLKCPVI
EECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCEE
LAINKVDNVVDKTALLPHIQFLSQQMNFLDVVPISAEKGTNVDAIARIVRQRLPQAEHHF
EEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHCC
PEEYITDRSQRFMASEIIREKLMRFLGEELPYSVTVEIERFAPNERGGYDIHGLILVERD
CHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCEEEEEEEEEEC
GQKKMVIGNKGSKIKTIGIEARQDMEAMFDAKVHLELWVKVKSGWADDERALRSLGYVDD
CCEEEEECCCCCEEEEEECCHHHHHHHHHCCEEEEEEEEEEECCCCCHHHHHHHCCCCCC
L
C
>Mature Secondary Structure 
SEEKTYCGFIAIVGRPNVGKSTLLNQLLGQKISITSRKPQTTRHRIMGIHTEGPYQAIY
CCCCCEEEEEEEECCCCCCHHHHHHHHHCCEEEECCCCCCCCHHHEEEEECCCCEEEEE
VDTPGLHIEEKRAINRLMNRAASSSIGDVELVIFVVEGTHWTPDDEMVLNKLRDLKCPVI
EECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCEE
LAINKVDNVVDKTALLPHIQFLSQQMNFLDVVPISAEKGTNVDAIARIVRQRLPQAEHHF
EEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHCC
PEEYITDRSQRFMASEIIREKLMRFLGEELPYSVTVEIERFAPNERGGYDIHGLILVERD
CHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCEEEEEEEEEEC
GQKKMVIGNKGSKIKTIGIEARQDMEAMFDAKVHLELWVKVKSGWADDERALRSLGYVDD
CCEEEEECCCCCEEEEEECCHHHHHHHHHCCEEEEEEEEEEECCCCCHHHHHHHCCCCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA