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The map label for this gene is bioC [H]

Identifier: 238920715

GI number: 238920715

Start: 2719520

End: 2720287

Strand: Reverse

Name: bioC [H]

Synonym: NT01EI_2828

Alternate gene names: 238920715

Gene position: 2720287-2719520 (Counterclockwise)

Preceding gene: 238920716

Following gene: 238920714

Centisome position: 71.36

GC content: 62.5

Gene sequence:

>768_bases
ATGAGTCAGTGTGACTGGGTAAACAAGCCAGCGCTGGCGGCCGCCTTTAGCCGCGCCGCGCACAGCTATGACGGTGCGGC
GGCCTTCCAGCGCCGCTGTGGGGAACGCCTGCTGGCGCTGTTACCGGCAGAGGGGTTGGGCCGGAAGGCGCTGGATGCCG
GCTGTGGCACCGGGTATTTCAGCCGTCGCCTGACAGCGATGGATTACCGGGCGACTGCGCTGGATTTGGCACCAGGGATG
TTGGCGCAGGCGCGACAGATCAACAGTGCACGCGATTATCTGTTGGCGGATATGGAGCATTTGCCGCTCTCTGCGGGCTG
TGTCGATCTCTGCTTTTGCAATCTGGCCATTCAGTGGTGCGCTTCGTTGCCCCGGGCGCTGTCTGAGCTGATGCGGGTCA
CCCGTCCGGGCGGACGTGTCGTATTCAGTACCCTGGCGGACGGGTCGCTGCAGGAGTTGGGGACAGCCTGGCTACAGGTG
GATGGACGGCGGCATGTGAACCCGTTTCTTTCCGTTGACCAGATTGCTGCGGCCTGCGCGCCTTACCATCACCGGCTGAC
CTTTCATCAAGAGCGTTGTTATTTTCCCGATGTGCTGGCGCTGATGCGCTCTCTGAAGGAGATCGGCGCGACGCATCTGC
ATGAGGGGCGCCATGGTGGCCTGAACGGACGGCAGCGTTTGGCCCGTCTGGCGCAGGTGTACCCGCGCGATGCGCATGGC
GTGGCGCTGAGTTATCAGCTTGTGGTTGGAGAATTGATGCGTGAATAG

Upstream 100 bases:

>100_bases
ATGCGTCCGCCCACCGTACCACCCGGCGGCGCGCGCCTGCGAATTACTCTGAGTGCAGCGCATTATCCGCAGGATATTGA
GCGGTTGCTGGAGGCATTGC

Downstream 100 bases:

>100_bases
GCAAGTGTGGAGCTGGTTTGTGACCGGTACCGATACCGATGTGGGGAAAACCGTGGTCAGCACCACGCTGCTGCAGGCGG
CGGCGTGCCGTGGGTTGACT

Product: biotin biosynthesis protein BioC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MSQCDWVNKPALAAAFSRAAHSYDGAAAFQRRCGERLLALLPAEGLGRKALDAGCGTGYFSRRLTAMDYRATALDLAPGM
LAQARQINSARDYLLADMEHLPLSAGCVDLCFCNLAIQWCASLPRALSELMRVTRPGGRVVFSTLADGSLQELGTAWLQV
DGRRHVNPFLSVDQIAAACAPYHHRLTFHQERCYFPDVLALMRSLKEIGATHLHEGRHGGLNGRQRLARLAQVYPRDAHG
VALSYQLVVGELMRE

Sequences:

>Translated_255_residues
MSQCDWVNKPALAAAFSRAAHSYDGAAAFQRRCGERLLALLPAEGLGRKALDAGCGTGYFSRRLTAMDYRATALDLAPGM
LAQARQINSARDYLLADMEHLPLSAGCVDLCFCNLAIQWCASLPRALSELMRVTRPGGRVVFSTLADGSLQELGTAWLQV
DGRRHVNPFLSVDQIAAACAPYHHRLTFHQERCYFPDVLALMRSLKEIGATHLHEGRHGGLNGRQRLARLAQVYPRDAHG
VALSYQLVVGELMRE
>Mature_254_residues
SQCDWVNKPALAAAFSRAAHSYDGAAAFQRRCGERLLALLPAEGLGRKALDAGCGTGYFSRRLTAMDYRATALDLAPGML
AQARQINSARDYLLADMEHLPLSAGCVDLCFCNLAIQWCASLPRALSELMRVTRPGGRVVFSTLADGSLQELGTAWLQVD
GRRHVNPFLSVDQIAAACAPYHHRLTFHQERCYFPDVLALMRSLKEIGATHLHEGRHGGLNGRQRLARLAQVYPRDAHGV
ALSYQLVVGELMRE

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786994, Length=249, Percent_Identity=46.9879518072289, Blast_Score=193, Evalue=8e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 28018; Mature: 27886

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQCDWVNKPALAAAFSRAAHSYDGAAAFQRRCGERLLALLPAEGLGRKALDAGCGTGYF
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHH
SRRLTAMDYRATALDLAPGMLAQARQINSARDYLLADMEHLPLSAGCVDLCFCNLAIQWC
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ASLPRALSELMRVTRPGGRVVFSTLADGSLQELGTAWLQVDGRRHVNPFLSVDQIAAACA
HHHHHHHHHHHHHHCCCCCEEEHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHC
PYHHRLTFHQERCYFPDVLALMRSLKEIGATHLHEGRHGGLNGRQRLARLAQVYPRDAHG
CHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCC
VALSYQLVVGELMRE
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQCDWVNKPALAAAFSRAAHSYDGAAAFQRRCGERLLALLPAEGLGRKALDAGCGTGYF
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHH
SRRLTAMDYRATALDLAPGMLAQARQINSARDYLLADMEHLPLSAGCVDLCFCNLAIQWC
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ASLPRALSELMRVTRPGGRVVFSTLADGSLQELGTAWLQVDGRRHVNPFLSVDQIAAACA
HHHHHHHHHHHHHHCCCCCEEEHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHC
PYHHRLTFHQERCYFPDVLALMRSLKEIGATHLHEGRHGGLNGRQRLARLAQVYPRDAHG
CHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCC
VALSYQLVVGELMRE
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8250549 [H]