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The map label for this gene is bioD [H]

Identifier: 238920714

GI number: 238920714

Start: 2718838

End: 2719500

Strand: Reverse

Name: bioD [H]

Synonym: NT01EI_2827

Alternate gene names: 238920714

Gene position: 2719500-2718838 (Counterclockwise)

Preceding gene: 238920715

Following gene: 238920713

Centisome position: 71.33

GC content: 64.4

Gene sequence:

>663_bases
GTGACCGGTACCGATACCGATGTGGGGAAAACCGTGGTCAGCACCACGCTGCTGCAGGCGGCGGCGTGCCGTGGGTTGAC
TACCGCCGGTTATAAACCGGTCGCCTCCGGCAGCCGTCTGTGCGCAGGCGCGCTGTGTAACGATGATGCACTGGCGCTGC
AGGCGGCGTCCAGCCTGCAGCTGCGCTATGCGCAGGTGAATCCCTATACCTTCGCCGAGGCGACCGCGCCGCACATCGTC
AGTGCCGAGGCGGAAACCCCCATCGACCCGCGGCGTCTCAGCGCCGGGCTGCGCTACCTGCAGCGTCGGGCGCAGTGGGT
GGTCGTGGAGGGGGCGGGTGGCTGGTTTACCCCCTTAAGTCTGGCGTATGGCTTCAATAGCTGGGTAGCGTCGGAAAAGC
TGCCGGTAATTTTGACCGTAGGCGTCAAGCTGGGCTGTATTAACCACGCCCTGCTCAGCGCCCACGCCATCGAAAGCGCC
GGGCTGAGGCTGGCCGGGTGGGTTGCTAATCAGGTACAGACTCCCGGGACTCGCCACGGCGAGTATCTGAACACACTGCA
TACGCTGTTGCCTGCTCCTTGTCTCGGGGAGATCCCGTTTGTACCTGGACAGGACAGTCTGGCGCGCGCTGCCTGTCTGG
ATTTGTCTGCGCTGCTGCCGTGA

Upstream 100 bases:

>100_bases
CTGGCGCAGGTGTACCCGCGCGATGCGCATGGCGTGGCGCTGAGTTATCAGCTTGTGGTTGGAGAATTGATGCGTGAATA
GGCAAGTGTGGAGCTGGTTT

Downstream 100 bases:

>100_bases
TGGCAGGTCACAGCGCTGTATATCCGGCGCTGTGGCGTTATTTTTCCTGTTTTATACTTAGCACAAATATAGTTTATTTT
TTATTTTCCCATCTAAAAAA

Product: dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MTGTDTDVGKTVVSTTLLQAAACRGLTTAGYKPVASGSRLCAGALCNDDALALQAASSLQLRYAQVNPYTFAEATAPHIV
SAEAETPIDPRRLSAGLRYLQRRAQWVVVEGAGGWFTPLSLAYGFNSWVASEKLPVILTVGVKLGCINHALLSAHAIESA
GLRLAGWVANQVQTPGTRHGEYLNTLHTLLPAPCLGEIPFVPGQDSLARAACLDLSALLP

Sequences:

>Translated_220_residues
MTGTDTDVGKTVVSTTLLQAAACRGLTTAGYKPVASGSRLCAGALCNDDALALQAASSLQLRYAQVNPYTFAEATAPHIV
SAEAETPIDPRRLSAGLRYLQRRAQWVVVEGAGGWFTPLSLAYGFNSWVASEKLPVILTVGVKLGCINHALLSAHAIESA
GLRLAGWVANQVQTPGTRHGEYLNTLHTLLPAPCLGEIPFVPGQDSLARAACLDLSALLP
>Mature_219_residues
TGTDTDVGKTVVSTTLLQAAACRGLTTAGYKPVASGSRLCAGALCNDDALALQAASSLQLRYAQVNPYTFAEATAPHIVS
AEAETPIDPRRLSAGLRYLQRRAQWVVVEGAGGWFTPLSLAYGFNSWVASEKLPVILTVGVKLGCINHALLSAHAIESAG
LRLAGWVANQVQTPGTRHGEYLNTLHTLLPAPCLGEIPFVPGQDSLARAACLDLSALLP

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=201, Percent_Identity=64.6766169154229, Blast_Score=261, Evalue=3e-71,
Organism=Escherichia coli, GI87081944, Length=203, Percent_Identity=47.7832512315271, Blast_Score=179, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 23077; Mature: 22945

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGTDTDVGKTVVSTTLLQAAACRGLTTAGYKPVASGSRLCAGALCNDDALALQAASSLQ
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHCCCE
LRYAQVNPYTFAEATAPHIVSAEAETPIDPRRLSAGLRYLQRRAQWVVVEGAGGWFTPLS
EEEEECCCEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHH
LAYGFNSWVASEKLPVILTVGVKLGCINHALLSAHAIESAGLRLAGWVANQVQTPGTRHG
HHHCCHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHCCCCCCCCH
EYLNTLHTLLPAPCLGEIPFVPGQDSLARAACLDLSALLP
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TGTDTDVGKTVVSTTLLQAAACRGLTTAGYKPVASGSRLCAGALCNDDALALQAASSLQ
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHCCCE
LRYAQVNPYTFAEATAPHIVSAEAETPIDPRRLSAGLRYLQRRAQWVVVEGAGGWFTPLS
EEEEECCCEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHH
LAYGFNSWVASEKLPVILTVGVKLGCINHALLSAHAIESAGLRLAGWVANQVQTPGTRHG
HHHCCHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHCCCCCCCCH
EYLNTLHTLLPAPCLGEIPFVPGQDSLARAACLDLSALLP
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]