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The map label for this gene is trpS [H]

Identifier: 238920532

GI number: 238920532

Start: 2538010

End: 2539041

Strand: Direct

Name: trpS [H]

Synonym: NT01EI_2644

Alternate gene names: 238920532

Gene position: 2538010-2539041 (Clockwise)

Preceding gene: 238920531

Following gene: 238920541

Centisome position: 66.57

GC content: 63.66

Gene sequence:

>1032_bases
ATGCCACACCTTTCTTCCCCCAACGACGCTGAACAGCACATCTGCCTGAGCGGCGATCGTCCCACCGGCCCACTGCACCT
CGGCCACTACGTCGGTTCCCTGCGCCAGCGCCTTACGCTGCAGCAACGATTCCCGCTGTATGTGATGATCGCCGATCTAC
AGGGACTCACTGACAACGGCAGTCAACCGCAAAAGGTGGCGGACAACATTCTACAGGTGATGGCAGACTATCTGGCAGTC
GGTATCGATCCCCAACGGGCTACGCTGTGCCTGCAGTCGGCGCTGCCCGCGCTGGCAGAGCTGACGATGCTGTATATGAA
TATCGTCAGCGTGGCGCGCGTGGCGCGGAACCCCACGGTAAAGGCCGAGATTGCCCAGAAAGGCTTTGCCAACTCGCTGC
CGGCCGGTTTTCTGCTCTACCCGATAAGTCAGGCCGCCGATATCACCGCGTTCGGCGCCGATCGCATCCCAGTCGGCGAT
GATCAGCTGCCGATGCTTGAGCAAACCAACGAGATCGTCCAGCGCATGAACACCCTTTTGCCACAGCCAGTGCTGCGTCC
CTGCCAGGCGATCCTCAGCCAGGTAGGGCGGCTACCGGGCATCGACGGCAACGCCAAGATGTCCAAATCCCTGGGGAATA
CCCTGCCGCTCAGCGCCGATCCCGCGCAGATCCGGGCGGCGGTTCACGCCATGTACACCGATCCCGCCCATCTGCGGGTC
AGCGATCCGGGACGGGTCGAGGGCAACGTCGTCTTCACCTATCTCGACGCCTTTCATCCCTGCGCCGAACGGGTGGCCGA
GATGAAGGCGCACTACCGCCGCGGTGGCCTCGGCGACAGCCAGTGTAAACGCGAGCTGGAGGAGTGTCTGCAGACCCTGC
TGGCGCCGATCCGTCAGCGGCGCGCCGAGCTGTTGGCGGATCGAGCCCAGCTGCTGCAGATCCTGCAGGCAGGAAGCGAA
CGGGCGCGCGAGGTCAGTCAGCAAACGCTGGTGGCGGTCAAACGGGGGCTGGGGCTGCCGCTGATGTACTGA

Upstream 100 bases:

>100_bases
TACTGTGTTCTTCTGATTTCAGTAACCAAGCCGCCGGAAGGCGACTTGGTATTTCCAATGGACGCACTCCGGCGCAGCTA
TCGATTAACGGAGAGCAACC

Downstream 100 bases:

>100_bases
GCCAGGATGGGAAAACAGGGAAGGGACGAAATAAAGGAGCGCGGGAGAAACAGGCGGCGCGTAAACGCCGCCGTACCGGT
CGTCAGAAACTGAGACCGAC

Product: tryptophanyl-tRNA synthetase II

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MPHLSSPNDAEQHICLSGDRPTGPLHLGHYVGSLRQRLTLQQRFPLYVMIADLQGLTDNGSQPQKVADNILQVMADYLAV
GIDPQRATLCLQSALPALAELTMLYMNIVSVARVARNPTVKAEIAQKGFANSLPAGFLLYPISQAADITAFGADRIPVGD
DQLPMLEQTNEIVQRMNTLLPQPVLRPCQAILSQVGRLPGIDGNAKMSKSLGNTLPLSADPAQIRAAVHAMYTDPAHLRV
SDPGRVEGNVVFTYLDAFHPCAERVAEMKAHYRRGGLGDSQCKRELEECLQTLLAPIRQRRAELLADRAQLLQILQAGSE
RAREVSQQTLVAVKRGLGLPLMY

Sequences:

>Translated_343_residues
MPHLSSPNDAEQHICLSGDRPTGPLHLGHYVGSLRQRLTLQQRFPLYVMIADLQGLTDNGSQPQKVADNILQVMADYLAV
GIDPQRATLCLQSALPALAELTMLYMNIVSVARVARNPTVKAEIAQKGFANSLPAGFLLYPISQAADITAFGADRIPVGD
DQLPMLEQTNEIVQRMNTLLPQPVLRPCQAILSQVGRLPGIDGNAKMSKSLGNTLPLSADPAQIRAAVHAMYTDPAHLRV
SDPGRVEGNVVFTYLDAFHPCAERVAEMKAHYRRGGLGDSQCKRELEECLQTLLAPIRQRRAELLADRAQLLQILQAGSE
RAREVSQQTLVAVKRGLGLPLMY
>Mature_342_residues
PHLSSPNDAEQHICLSGDRPTGPLHLGHYVGSLRQRLTLQQRFPLYVMIADLQGLTDNGSQPQKVADNILQVMADYLAVG
IDPQRATLCLQSALPALAELTMLYMNIVSVARVARNPTVKAEIAQKGFANSLPAGFLLYPISQAADITAFGADRIPVGDD
QLPMLEQTNEIVQRMNTLLPQPVLRPCQAILSQVGRLPGIDGNAKMSKSLGNTLPLSADPAQIRAAVHAMYTDPAHLRVS
DPGRVEGNVVFTYLDAFHPCAERVAEMKAHYRRGGLGDSQCKRELEECLQTLLAPIRQRRAELLADRAQLLQILQAGSER
AREVSQQTLVAVKRGLGLPLMY

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=341, Percent_Identity=26.6862170087977, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI41352700, Length=188, Percent_Identity=29.2553191489362, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1789786, Length=333, Percent_Identity=27.9279279279279, Blast_Score=121, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI71982800, Length=335, Percent_Identity=25.0746268656716, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71982793, Length=335, Percent_Identity=25.0746268656716, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6320474, Length=345, Percent_Identity=25.5072463768116, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24666151, Length=356, Percent_Identity=30.3370786516854, Blast_Score=127, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37490; Mature: 37359

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHLSSPNDAEQHICLSGDRPTGPLHLGHYVGSLRQRLTLQQRFPLYVMIADLQGLTDNG
CCCCCCCCCHHHCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC
SQPQKVADNILQVMADYLAVGIDPQRATLCLQSALPALAELTMLYMNIVSVARVARNPTV
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
KAEIAQKGFANSLPAGFLLYPISQAADITAFGADRIPVGDDQLPMLEQTNEIVQRMNTLL
HHHHHHHCCCCCCCCCCEEEECHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHC
PQPVLRPCQAILSQVGRLPGIDGNAKMSKSLGNTLPLSADPAQIRAAVHAMYTDPAHLRV
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
SDPGRVEGNVVFTYLDAFHPCAERVAEMKAHYRRGGLGDSQCKRELEECLQTLLAPIRQR
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RAELLADRAQLLQILQAGSERAREVSQQTLVAVKRGLGLPLMY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PHLSSPNDAEQHICLSGDRPTGPLHLGHYVGSLRQRLTLQQRFPLYVMIADLQGLTDNG
CCCCCCCCHHHCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC
SQPQKVADNILQVMADYLAVGIDPQRATLCLQSALPALAELTMLYMNIVSVARVARNPTV
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
KAEIAQKGFANSLPAGFLLYPISQAADITAFGADRIPVGDDQLPMLEQTNEIVQRMNTLL
HHHHHHHCCCCCCCCCCEEEECHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHC
PQPVLRPCQAILSQVGRLPGIDGNAKMSKSLGNTLPLSADPAQIRAAVHAMYTDPAHLRV
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
SDPGRVEGNVVFTYLDAFHPCAERVAEMKAHYRRGGLGDSQCKRELEECLQTLLAPIRQR
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
RAELLADRAQLLQILQAGSERAREVSQQTLVAVKRGLGLPLMY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA