Click here to switch to the map view.

The map label for this gene is hcr [H]

Identifier: 238920391

GI number: 238920391

Start: 2396949

End: 2397914

Strand: Direct

Name: hcr [H]

Synonym: NT01EI_2501

Alternate gene names: 238920391

Gene position: 2396949-2397914 (Clockwise)

Preceding gene: 238920390

Following gene: 238920396

Centisome position: 62.87

GC content: 64.6

Gene sequence:

>966_bases
ATGCAGGTTCACTCTCTGCGCCGGGAGACCCCCGATGTCTGGACGCTAAACCTGATCTGTCCCGACTTTTATCCCTACCG
TCCCGGTCAGTATGCACTGGTCAGCATCGACGGCAGCGAAGAGACCCTGCGTGCCTACACGCTCTCCTCAACCCCAGGGC
TCAGCCCCTTTATTACCCTGACGGTACGCCGCCTGGACAACGGCGTCGGCTCCGGCTGGCTGACCGGCCGGGTACGGCCG
GGTGACGAACTGTGGCTTTCACCGGCGCAGGGCAGCTTCACCTGCCCGCAGGCGGACGCCACCCGCTATCTGATGCTGGC
AGCCGGGTGCGGCGTAACCCCGATCATCTCCATGACCCGCTGGCTGCTGGTTAACCGACCCAGCACGGATGTCGCGGTGA
TCTACGCGGTCCGTACACCGCGCGACCTGATCTTCGCCGACGAGTGGCACCAGCTGGCCGATGCTCACCCGCAGCTGCAA
CTGATCCTGCTGGCCGAAGCGGAAGCAACAGGCGCTATCCTGCCGGGACGCCTAAATCGCGGGGTGCTACAGGGCCAGAT
CCGCGCCCTGACGGAGCGTACGGTGATGATCTGCGGCCCGGCGCCCTATATGCAGCAGGCTCAGACCCTGGTTGGTGAAC
TGGGGGTCAGCCCACAGCGGGTGCATCAGGAGATCTTTCGCCCGCAGGTGGGAAACAGCTGCGGCGGCGATCTGCGCATA
ACTTCCTGCAGCCACCCCGGCGAATATCGTACCGCCGTCGGCGTTACCCTGTTGCACGCCATGGAGCAGAACCGGCTGCC
GGTACAGGCCGCCTGCCGCGCCGGGGTCTGTGGCTGCTGTAAGACCCGTATCCTGCACGGTGACTATCAGGTCAGCAGCA
CCATGACCCTCACCCCGCAGGAGATAGCCCAGGGCTATGTATTGGCCTGCAGCTGCCAGCTGGAGAGTGACATTACGCTG
GCCTGA

Upstream 100 bases:

>100_bases
CCGGCAATCTGAAGTGCCCCGAGCCGTCTGGTACGGGGCGAAATACTGACTGCGAGACGCCATCACCATGACCATGCCAA
CCCCCCTTTGCCCCCACCGG

Downstream 100 bases:

>100_bases
TAACAGTATCCCCACTCCGGTACAACGAGCCAAAGCGGCCATGGGCAGGGCACCGCATGATCATCAATGGTATGTTCTGG
GTGCTTTGTTCAGACGCACC

Product: HCP oxidoreductase, NADH-dependent

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MQVHSLRRETPDVWTLNLICPDFYPYRPGQYALVSIDGSEETLRAYTLSSTPGLSPFITLTVRRLDNGVGSGWLTGRVRP
GDELWLSPAQGSFTCPQADATRYLMLAAGCGVTPIISMTRWLLVNRPSTDVAVIYAVRTPRDLIFADEWHQLADAHPQLQ
LILLAEAEATGAILPGRLNRGVLQGQIRALTERTVMICGPAPYMQQAQTLVGELGVSPQRVHQEIFRPQVGNSCGGDLRI
TSCSHPGEYRTAVGVTLLHAMEQNRLPVQAACRAGVCGCCKTRILHGDYQVSSTMTLTPQEIAQGYVLACSCQLESDITL
A

Sequences:

>Translated_321_residues
MQVHSLRRETPDVWTLNLICPDFYPYRPGQYALVSIDGSEETLRAYTLSSTPGLSPFITLTVRRLDNGVGSGWLTGRVRP
GDELWLSPAQGSFTCPQADATRYLMLAAGCGVTPIISMTRWLLVNRPSTDVAVIYAVRTPRDLIFADEWHQLADAHPQLQ
LILLAEAEATGAILPGRLNRGVLQGQIRALTERTVMICGPAPYMQQAQTLVGELGVSPQRVHQEIFRPQVGNSCGGDLRI
TSCSHPGEYRTAVGVTLLHAMEQNRLPVQAACRAGVCGCCKTRILHGDYQVSSTMTLTPQEIAQGYVLACSCQLESDITL
A
>Mature_321_residues
MQVHSLRRETPDVWTLNLICPDFYPYRPGQYALVSIDGSEETLRAYTLSSTPGLSPFITLTVRRLDNGVGSGWLTGRVRP
GDELWLSPAQGSFTCPQADATRYLMLAAGCGVTPIISMTRWLLVNRPSTDVAVIYAVRTPRDLIFADEWHQLADAHPQLQ
LILLAEAEATGAILPGRLNRGVLQGQIRALTERTVMICGPAPYMQQAQTLVGELGVSPQRVHQEIFRPQVGNSCGGDLRI
TSCSHPGEYRTAVGVTLLHAMEQNRLPVQAACRAGVCGCCKTRILHGDYQVSSTMTLTPQEIAQGYVLACSCQLESDITL
A

Specific function: NADH oxidoreductase acting in concert with HCP [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787098, Length=321, Percent_Identity=57.0093457943925, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1787658, Length=346, Percent_Identity=30.3468208092486, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788104, Length=316, Percent_Identity=26.8987341772152, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788903, Length=213, Percent_Identity=28.169014084507, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35049; Mature: 35049

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVHSLRRETPDVWTLNLICPDFYPYRPGQYALVSIDGSEETLRAYTLSSTPGLSPFITL
CCCCHHHCCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCEEEE
TVRRLDNGVGSGWLTGRVRPGDELWLSPAQGSFTCPQADATRYLMLAAGCGVTPIISMTR
EEEHHCCCCCCCEEEEEECCCHHEEECCCCCCEECCCCCCCEEEEEECCCCCHHHHHHHE
WLLVNRPSTDVAVIYAVRTPRDLIFADEWHQLADAHPQLQLILLAEAEATGAILPGRLNR
EEEEECCCCCEEEEEEEECCCCEEEEHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCC
GVLQGQIRALTERTVMICGPAPYMQQAQTLVGELGVSPQRVHQEIFRPQVGNSCGGDLRI
CHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCEEE
TSCSHPGEYRTAVGVTLLHAMEQNRLPVQAACRAGVCGCCKTRILHGDYQVSSTMTLTPQ
EECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHEEEECCEEECCEEEECHH
EIAQGYVLACSCQLESDITLA
HHHCCEEEEEEEEECCCCCCC
>Mature Secondary Structure
MQVHSLRRETPDVWTLNLICPDFYPYRPGQYALVSIDGSEETLRAYTLSSTPGLSPFITL
CCCCHHHCCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCEEEE
TVRRLDNGVGSGWLTGRVRPGDELWLSPAQGSFTCPQADATRYLMLAAGCGVTPIISMTR
EEEHHCCCCCCCEEEEEECCCHHEEECCCCCCEECCCCCCCEEEEEECCCCCHHHHHHHE
WLLVNRPSTDVAVIYAVRTPRDLIFADEWHQLADAHPQLQLILLAEAEATGAILPGRLNR
EEEEECCCCCEEEEEEEECCCCEEEEHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCC
GVLQGQIRALTERTVMICGPAPYMQQAQTLVGELGVSPQRVHQEIFRPQVGNSCGGDLRI
CHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCEEE
TSCSHPGEYRTAVGVTLLHAMEQNRLPVQAACRAGVCGCCKTRILHGDYQVSSTMTLTPQ
EECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHEEEECCEEECCEEEECHH
EIAQGYVLACSCQLESDITLA
HHHCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10651802 [H]