Click here to switch to the map view.

The map label for this gene is pabC [H]

Identifier: 238920257

GI number: 238920257

Start: 2268068

End: 2268880

Strand: Reverse

Name: pabC [H]

Synonym: NT01EI_2366

Alternate gene names: 238920257

Gene position: 2268880-2268068 (Counterclockwise)

Preceding gene: 238920258

Following gene: 238920256

Centisome position: 59.51

GC content: 63.22

Gene sequence:

>813_bases
ATGTATTGGCTTGATGGAGAAGAGTGCCAGCAGATCGACCTGCGCGATCGCGGGCTGCAGTATGGCGACGGCTGTTTTAC
CACGGCCCGCATCGTCAATGGCCGGGTCGACGGGCTACAGGCGCATCTGACCCGGATGCAGCGCGCCTGCGAACGCCTGA
TGATCCATGGTGTGGCCTGGCCGCGCTGGCAGGCCGAGGCTGAGCAGTATGCGGCGACCCGCGATGAGGGTGTCCTGAAG
GCGATCGTTACCCGCGGCTGCGGTGGCCGGGGCTATGATCCTACCGGGAGCCATTCGCCGCGCCGGATCTTCAGTACAGC
ACCGCTCCCTTCACACTATCCGGCGCTGCGTGAGCGGGGGATAAACCTGATCGTGAGTCCGGTCAGACTGGCGCATCAAC
CGTTGTTGGCGGGGATCAAACATCTGAATCGGTTAGAGCAGGTGCTGATCCGGGCCAGCCTGGCGCAGACACAGGCGGAT
GAGGCGCTGGTGCTTGACACTCAGGATAACCTGGTGGAGTGCTGTGCGGCCAATCTGTTCTGGCGCAGTGGTCAGCAGGT
GTTTACCCCGCGCCTGACCCGCTGCGGCGTGGATGGGCTGATGCGTCAGCGCATCTGTCGGGTGCTGGCGCACAGCGGGT
ATCACCTTGCCGAGGTCGATGCCGGTCTGCCGTCCCTGCTGGCGGCCGATGAAGTCGTGGTGTGCAATGCGCTGATGCCG
TTGCTGCCGGTGCGCCGGGTGGCAACGCAGGTTTTCAGCGATCGCACGCTGTATCAATTTTTATTACCGCACTGCCTGCA
GGTTGAGGCATAG

Upstream 100 bases:

>100_bases
AGGTGTAATGGCGTATCGTTGGGAAATGGCTCCTTCGGGGGCCATTTTTTTATCCCGGCGGTTAGAATAGGGTGATGTGC
ACGAACGAAGGGAGAGGCGA

Downstream 100 bases:

>100_bases
CGGTGTGATGGCGGTTGAATGAAGAGAAAATGGATAGCCTGGATTGCGGCGTTGGTGCTGCTGTTGCTGGGCGCTATAGG
TGTGATGGGGTATCACCAGG

Product: aminodeoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MYWLDGEECQQIDLRDRGLQYGDGCFTTARIVNGRVDGLQAHLTRMQRACERLMIHGVAWPRWQAEAEQYAATRDEGVLK
AIVTRGCGGRGYDPTGSHSPRRIFSTAPLPSHYPALRERGINLIVSPVRLAHQPLLAGIKHLNRLEQVLIRASLAQTQAD
EALVLDTQDNLVECCAANLFWRSGQQVFTPRLTRCGVDGLMRQRICRVLAHSGYHLAEVDAGLPSLLAADEVVVCNALMP
LLPVRRVATQVFSDRTLYQFLLPHCLQVEA

Sequences:

>Translated_270_residues
MYWLDGEECQQIDLRDRGLQYGDGCFTTARIVNGRVDGLQAHLTRMQRACERLMIHGVAWPRWQAEAEQYAATRDEGVLK
AIVTRGCGGRGYDPTGSHSPRRIFSTAPLPSHYPALRERGINLIVSPVRLAHQPLLAGIKHLNRLEQVLIRASLAQTQAD
EALVLDTQDNLVECCAANLFWRSGQQVFTPRLTRCGVDGLMRQRICRVLAHSGYHLAEVDAGLPSLLAADEVVVCNALMP
LLPVRRVATQVFSDRTLYQFLLPHCLQVEA
>Mature_270_residues
MYWLDGEECQQIDLRDRGLQYGDGCFTTARIVNGRVDGLQAHLTRMQRACERLMIHGVAWPRWQAEAEQYAATRDEGVLK
AIVTRGCGGRGYDPTGSHSPRRIFSTAPLPSHYPALRERGINLIVSPVRLAHQPLLAGIKHLNRLEQVLIRASLAQTQAD
EALVLDTQDNLVECCAANLFWRSGQQVFTPRLTRCGVDGLMRQRICRVLAHSGYHLAEVDAGLPSLLAADEVVVCNALMP
LLPVRRVATQVFSDRTLYQFLLPHCLQVEA

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=265, Percent_Identity=53.2075471698113, Blast_Score=291, Evalue=3e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 30146; Mature: 30146

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYWLDGEECQQIDLRDRGLQYGDGCFTTARIVNGRVDGLQAHLTRMQRACERLMIHGVAW
CCCCCCHHHHCCCHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PRWQAEAEQYAATRDEGVLKAIVTRGCGGRGYDPTGSHSPRRIFSTAPLPSHYPALRERG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHEECCCCCCCCHHHHHCC
INLIVSPVRLAHQPLLAGIKHLNRLEQVLIRASLAQTQADEALVLDTQDNLVECCAANLF
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHH
WRSGQQVFTPRLTRCGVDGLMRQRICRVLAHSGYHLAEVDAGLPSLLAADEVVVCNALMP
HHCCCHHHCCHHHHCCHHHHHHHHHHHHHHHCCCEEEHHCCCCHHHHHHHHHHHHHHHHH
LLPVRRVATQVFSDRTLYQFLLPHCLQVEA
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYWLDGEECQQIDLRDRGLQYGDGCFTTARIVNGRVDGLQAHLTRMQRACERLMIHGVAW
CCCCCCHHHHCCCHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PRWQAEAEQYAATRDEGVLKAIVTRGCGGRGYDPTGSHSPRRIFSTAPLPSHYPALRERG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHEECCCCCCCCHHHHHCC
INLIVSPVRLAHQPLLAGIKHLNRLEQVLIRASLAQTQADEALVLDTQDNLVECCAANLF
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHH
WRSGQQVFTPRLTRCGVDGLMRQRICRVLAHSGYHLAEVDAGLPSLLAADEVVVCNALMP
HHCCCHHHCCHHHHCCHHHHHHHHHHHHHHHCCCEEEHHCCCCHHHHHHHHHHHHHHHHH
LLPVRRVATQVFSDRTLYQFLLPHCLQVEA
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1644759; 8905232; 9278503; 2071583; 2251281; 10876155 [H]