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The map label for this gene is fabF [H]

Identifier: 238920258

GI number: 238920258

Start: 2268973

End: 2270193

Strand: Reverse

Name: fabF [H]

Synonym: NT01EI_2367

Alternate gene names: 238920258

Gene position: 2270193-2268973 (Counterclockwise)

Preceding gene: 238920259

Following gene: 238920257

Centisome position: 59.55

GC content: 60.69

Gene sequence:

>1221_bases
GTGACCGGACTGGGCATGTTGTCTCCTGTCGGCAATACCGTAGATTCCACATGGAATGCGATTCTTGCCGGTCAGAGTGG
CATCAGCCTGATCGACCATTTCGATACTAGCGCCTATGCAACGCGTTTTGCTGGCTTAGTAAAGGATTTTAATTGCGAAG
AGCATATTTCGCGCAAAGAGGCGCGGAAGATGGATCTCTTCATTCAGTACGGGATCATGGCCGGTATTCAGGCCTTCCAA
GACTCCGGGCTGGAGATTACGGAAGAAAACGCCCCGCGTATTGGCGCCGCTATCGGCTCCGGGATCGGCGGCCTCGGCCT
GATCGAAGAAAACCACAGTGCGCTGATGCACGGTGGCCCGCGTAAGATCAGCCCGTTTTTCGTTCCATCAACCATCGTCA
ACATGGTGGCCGGGCATCTGTCCATCATGCTGGGGCTGCGTGGACCGAGCATCTCGATTGCGACGGCCTGCACCTCTGGC
GTGCATAACATTGGCCACGCGGCGCGAATGATCGCGTATGGCGACGCCGATGCCATGCTGGCTGGCGGCGCAGAAAAGGC
GAGTACGCAGCTGGGCGTCGGCGGATTTGGCGCCGCGCGTGCGCTCTCGACCCGCAATGATAACCCGCAGGCGGCGAGCC
GTCCGTGGGACAAAGATCGCGACGGCTTCGTGCTGGGCGATGGCGCCGGCATTCTGGTGCTGGAAGAGTATGAACATGCC
AAGGCGCGTGGTGCCAAGATCTATGCCGAGCTGGTTGGCTTTGGCATGAGCAGCGATGCCTATCACATGACGTCCCCACC
GGCCGATGGCGCCGGTGCGGCGCAGGCGATGGAAAACGCCTTGCGTGACGCGGGTGTGACGCCGGCACAAGTCGGCTATA
TCAACGCCCACGGCACCTCTACGGCGGCCGGCGATAAGGCGGAGACCCAGGCGGTCAAGAATGTCTACGGCGCCGACGTG
GCCCGTGTGATGGTCAGCTCGACCAAGTCGATGACCGGCCACCTGCTGGGTGCCGCTGGCGCGGTAGAGTCCATCTTTAC
CATTCTGGCGCTGCGCGATCAGGTGATCCCGCCGACCATTAACCTGGACAACCCGGATGAGGGTTGCGATCTGGACTTCG
TTCCGCACGAAGCCCGTCAGGTCAGCGGCCTGGAGTATGCGCTGTGCAACTCCTTTGGCTTCGGCGGTACCAACGGCTCC
ATTATCTTCCGCAAGGTGTAA

Upstream 100 bases:

>100_bases
AACTCATCTAGGCGGTCATTCGACCGCCTACGTTTTTCCTGCATTCATCAAGTATCACTTCCCTCCCTGGAGGACAAACG
TGTCTAAGCGTCGAGTTGTT

Downstream 100 bases:

>100_bases
TGGCGTATCGTTGGGAAATGGCTCCTTCGGGGGCCATTTTTTTATCCCGGCGGTTAGAATAGGGTGATGTGCACGAACGA
AGGGAGAGGCGAATGTATTG

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MTGLGMLSPVGNTVDSTWNAILAGQSGISLIDHFDTSAYATRFAGLVKDFNCEEHISRKEARKMDLFIQYGIMAGIQAFQ
DSGLEITEENAPRIGAAIGSGIGGLGLIEENHSALMHGGPRKISPFFVPSTIVNMVAGHLSIMLGLRGPSISIATACTSG
VHNIGHAARMIAYGDADAMLAGGAEKASTQLGVGGFGAARALSTRNDNPQAASRPWDKDRDGFVLGDGAGILVLEEYEHA
KARGAKIYAELVGFGMSSDAYHMTSPPADGAGAAQAMENALRDAGVTPAQVGYINAHGTSTAAGDKAETQAVKNVYGADV
ARVMVSSTKSMTGHLLGAAGAVESIFTILALRDQVIPPTINLDNPDEGCDLDFVPHEARQVSGLEYALCNSFGFGGTNGS
IIFRKV

Sequences:

>Translated_406_residues
MTGLGMLSPVGNTVDSTWNAILAGQSGISLIDHFDTSAYATRFAGLVKDFNCEEHISRKEARKMDLFIQYGIMAGIQAFQ
DSGLEITEENAPRIGAAIGSGIGGLGLIEENHSALMHGGPRKISPFFVPSTIVNMVAGHLSIMLGLRGPSISIATACTSG
VHNIGHAARMIAYGDADAMLAGGAEKASTQLGVGGFGAARALSTRNDNPQAASRPWDKDRDGFVLGDGAGILVLEEYEHA
KARGAKIYAELVGFGMSSDAYHMTSPPADGAGAAQAMENALRDAGVTPAQVGYINAHGTSTAAGDKAETQAVKNVYGADV
ARVMVSSTKSMTGHLLGAAGAVESIFTILALRDQVIPPTINLDNPDEGCDLDFVPHEARQVSGLEYALCNSFGFGGTNGS
IIFRKV
>Mature_405_residues
TGLGMLSPVGNTVDSTWNAILAGQSGISLIDHFDTSAYATRFAGLVKDFNCEEHISRKEARKMDLFIQYGIMAGIQAFQD
SGLEITEENAPRIGAAIGSGIGGLGLIEENHSALMHGGPRKISPFFVPSTIVNMVAGHLSIMLGLRGPSISIATACTSGV
HNIGHAARMIAYGDADAMLAGGAEKASTQLGVGGFGAARALSTRNDNPQAASRPWDKDRDGFVLGDGAGILVLEEYEHAK
ARGAKIYAELVGFGMSSDAYHMTSPPADGAGAAQAMENALRDAGVTPAQVGYINAHGTSTAAGDKAETQAVKNVYGADVA
RVMVSSTKSMTGHLLGAAGAVESIFTILALRDQVIPPTINLDNPDEGCDLDFVPHEARQVSGLEYALCNSFGFGGTNGSI
IFRKV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=410, Percent_Identity=43.6585365853659, Blast_Score=327, Evalue=1e-89,
Organism=Homo sapiens, GI223972627, Length=145, Percent_Identity=50.3448275862069, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI41872631, Length=282, Percent_Identity=28.3687943262411, Blast_Score=89, Evalue=5e-18,
Organism=Escherichia coli, GI1787337, Length=406, Percent_Identity=86.6995073891626, Blast_Score=685, Evalue=0.0,
Organism=Escherichia coli, GI1788663, Length=412, Percent_Identity=38.1067961165049, Blast_Score=231, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI71983541, Length=409, Percent_Identity=38.1418092909535, Blast_Score=267, Evalue=7e-72,
Organism=Caenorhabditis elegans, GI71983535, Length=264, Percent_Identity=45.0757575757576, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI212642053, Length=362, Percent_Identity=25.1381215469613, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17550940, Length=350, Percent_Identity=24.5714285714286, Blast_Score=105, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6320904, Length=438, Percent_Identity=39.2694063926941, Blast_Score=289, Evalue=6e-79,
Organism=Drosophila melanogaster, GI24644341, Length=421, Percent_Identity=42.7553444180523, Blast_Score=328, Evalue=5e-90,
Organism=Drosophila melanogaster, GI19920632, Length=378, Percent_Identity=24.3386243386243, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI221330659, Length=378, Percent_Identity=24.3386243386243, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24581345, Length=360, Percent_Identity=23.3333333333333, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42202; Mature: 42071

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLGMLSPVGNTVDSTWNAILAGQSGISLIDHFDTSAYATRFAGLVKDFNCEEHISRKE
CCCCCCCCCCCCCHHHHHHEEEECCCCCHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHH
ARKMDLFIQYGIMAGIQAFQDSGLEITEENAPRIGAAIGSGIGGLGLIEENHSALMHGGP
HHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHCCCCCCEEEECCCCHHHCCCC
RKISPFFVPSTIVNMVAGHLSIMLGLRGPSISIATACTSGVHNIGHAARMIAYGDADAML
CCCCCEECHHHHHHHHHHHHHEEEECCCCCEEEHHHHHHHHHHHHHHHHEEEECCCCCEE
AGGAEKASTQLGVGGFGAARALSTRNDNPQAASRPWDKDRDGFVLGDGAGILVLEEYEHA
ECCCHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCHHH
KARGAKIYAELVGFGMSSDAYHMTSPPADGAGAAQAMENALRDAGVTPAQVGYINAHGTS
HHCCHHHHHHHHCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCCCHHEEEEECCCCC
TAAGDKAETQAVKNVYGADVARVMVSSTKSMTGHLLGAAGAVESIFTILALRDQVIPPTI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NLDNPDEGCDLDFVPHEARQVSGLEYALCNSFGFGGTNGSIIFRKV
CCCCCCCCCCCCCCCCHHHHHCCCCEEHHCCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
TGLGMLSPVGNTVDSTWNAILAGQSGISLIDHFDTSAYATRFAGLVKDFNCEEHISRKE
CCCCCCCCCCCCHHHHHHEEEECCCCCHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHH
ARKMDLFIQYGIMAGIQAFQDSGLEITEENAPRIGAAIGSGIGGLGLIEENHSALMHGGP
HHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHCCCCCCEEEECCCCHHHCCCC
RKISPFFVPSTIVNMVAGHLSIMLGLRGPSISIATACTSGVHNIGHAARMIAYGDADAML
CCCCCEECHHHHHHHHHHHHHEEEECCCCCEEEHHHHHHHHHHHHHHHHEEEECCCCCEE
AGGAEKASTQLGVGGFGAARALSTRNDNPQAASRPWDKDRDGFVLGDGAGILVLEEYEHA
ECCCHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCHHH
KARGAKIYAELVGFGMSSDAYHMTSPPADGAGAAQAMENALRDAGVTPAQVGYINAHGTS
HHCCHHHHHHHHCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCCCHHEEEEECCCCC
TAAGDKAETQAVKNVYGADVARVMVSSTKSMTGHLLGAAGAVESIFTILALRDQVIPPTI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NLDNPDEGCDLDFVPHEARQVSGLEYALCNSFGFGGTNGSIIFRKV
CCCCCCCCCCCCCCCCHHHHHCCCCEEHHCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]