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The map label for this gene is atoA [H]

Identifier: 238920101

GI number: 238920101

Start: 2126895

End: 2127545

Strand: Direct

Name: atoA [H]

Synonym: NT01EI_2207

Alternate gene names: 238920101

Gene position: 2126895-2127545 (Clockwise)

Preceding gene: 238920100

Following gene: 238920102

Centisome position: 55.79

GC content: 63.59

Gene sequence:

>651_bases
ATGGATGCGAAACAGCGTATTGCGCGCCGCGTGGCGCGAGAGCTGCACGATGGCGACATCGTCAATCTGGGCATCGGCCT
GCCGACGATGGTCGCCAATTATCTGCCGCAGGGTATCCACATCACCCTGCAATCGGAAAACGGATTCCTCGGGCTGGGGC
CGGTCACCACCGCCCACCCCGATCTGGTGAACGCCGGGGGACAGCCCTGCGGGATTTTACCGGGCGCGGCCATGTTCGAC
AGCGCGCTGTCGTTCGCCCTGATCCGCGGCGGTCACGTGGACGCCTGCGTACTGGGTGGGCTGCAGGTCGATGAACAGGC
CAGCCTCGCCAACTGGGTGGTTCCCGGCAAAATGGTGCCGGGCATGGGGGGTGCGATGGATCTGGTCACCGGGGCGCGCA
AAGTCATTATTGCCATGGAGCACTGCGCGAAAGATGGCGCGGCGAAAATTCTGCGTAATTGCACCATGCCACTCACCGCC
CGCCATGCGGTGCATGTGCTGGTCACCGAACTGGCGGTATTCCGCTTTACGGACGGCAAAATGTGGCTGACCGAACTCGC
CGCAGGGTGCGATCTGGCCACCCTGCGCACCAAGACCGAGGCCCATTTTGACGTCGCCGCCGACCTGTTGATCATGCGGG
GTGACGCATGA

Upstream 100 bases:

>100_bases
AGCCGGACGAACTGGTGGAGACCGGTGCGCTGCTGCCTGACCACATCGTGACGCCCGGCGCAGTCATCGACCATATCGTC
CTGCCTCAGGAGAATAAATA

Downstream 100 bases:

>100_bases
TTGGCCGCATCTCACGTTTTATGGCCCGCTTCGTTAGCCGCTGGCTGCCCGATCCGCTGATTTTCGCCATGCTGCTGACC
CTGCTGACCTTCGCTATCGC

Product: acetate CoA-transferase subunit beta

Products: NA

Alternate protein names: Acetyl-CoA:acetoacetate-CoA transferase subunit beta [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MDAKQRIARRVARELHDGDIVNLGIGLPTMVANYLPQGIHITLQSENGFLGLGPVTTAHPDLVNAGGQPCGILPGAAMFD
SALSFALIRGGHVDACVLGGLQVDEQASLANWVVPGKMVPGMGGAMDLVTGARKVIIAMEHCAKDGAAKILRNCTMPLTA
RHAVHVLVTELAVFRFTDGKMWLTELAAGCDLATLRTKTEAHFDVAADLLIMRGDA

Sequences:

>Translated_216_residues
MDAKQRIARRVARELHDGDIVNLGIGLPTMVANYLPQGIHITLQSENGFLGLGPVTTAHPDLVNAGGQPCGILPGAAMFD
SALSFALIRGGHVDACVLGGLQVDEQASLANWVVPGKMVPGMGGAMDLVTGARKVIIAMEHCAKDGAAKILRNCTMPLTA
RHAVHVLVTELAVFRFTDGKMWLTELAAGCDLATLRTKTEAHFDVAADLLIMRGDA
>Mature_216_residues
MDAKQRIARRVARELHDGDIVNLGIGLPTMVANYLPQGIHITLQSENGFLGLGPVTTAHPDLVNAGGQPCGILPGAAMFD
SALSFALIRGGHVDACVLGGLQVDEQASLANWVVPGKMVPGMGGAMDLVTGARKVIIAMEHCAKDGAAKILRNCTMPLTA
RHAVHVLVTELAVFRFTDGKMWLTELAAGCDLATLRTKTEAHFDVAADLLIMRGDA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG2057

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit B family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=217, Percent_Identity=47.926267281106, Blast_Score=200, Evalue=8e-52,
Organism=Homo sapiens, GI11545841, Length=217, Percent_Identity=45.1612903225806, Blast_Score=187, Evalue=6e-48,
Organism=Escherichia coli, GI1788552, Length=215, Percent_Identity=89.3023255813954, Blast_Score=400, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17531517, Length=217, Percent_Identity=45.6221198156682, Blast_Score=181, Evalue=2e-46,
Organism=Drosophila melanogaster, GI21358325, Length=214, Percent_Identity=49.5327102803738, Blast_Score=211, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24655794, Length=214, Percent_Identity=49.5327102803738, Blast_Score=211, Evalue=3e-55,

Paralogues:

None

Copy number: 369 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012791
- InterPro:   IPR004165
- InterPro:   IPR004164 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.8 [H]

Molecular weight: Translated: 22771; Mature: 22771

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS01274 COA_TRANSF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAKQRIARRVARELHDGDIVNLGIGLPTMVANYLPQGIHITLQSENGFLGLGPVTTAHP
CCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCC
DLVNAGGQPCGILPGAAMFDSALSFALIRGGHVDACVLGGLQVDEQASLANWVVPGKMVP
HHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHCCCCCCCCC
GMGGAMDLVTGARKVIIAMEHCAKDGAAKILRNCTMPLTARHAVHVLVTELAVFRFTDGK
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEECCCC
MWLTELAAGCDLATLRTKTEAHFDVAADLLIMRGDA
HHHHHHHCCCCCHHHHCCCHHHHHHHEEEEEEECCC
>Mature Secondary Structure
MDAKQRIARRVARELHDGDIVNLGIGLPTMVANYLPQGIHITLQSENGFLGLGPVTTAHP
CCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCC
DLVNAGGQPCGILPGAAMFDSALSFALIRGGHVDACVLGGLQVDEQASLANWVVPGKMVP
HHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHCCCCCCCCC
GMGGAMDLVTGARKVIIAMEHCAKDGAAKILRNCTMPLTARHAVHVLVTELAVFRFTDGK
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEECCCC
MWLTELAAGCDLATLRTKTEAHFDVAADLLIMRGDA
HHHHHHHCCCCCHHHHCCCHHHHHHHEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]