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The map label for this gene is atoD [H]

Identifier: 238920100

GI number: 238920100

Start: 2126233

End: 2126895

Strand: Direct

Name: atoD [H]

Synonym: NT01EI_2206

Alternate gene names: 238920100

Gene position: 2126233-2126895 (Clockwise)

Preceding gene: 238920098

Following gene: 238920101

Centisome position: 55.77

GC content: 65.16

Gene sequence:

>663_bases
ATGAAAACCAAGTTGATTACTTTACAGAGTGCCACCGGGCTGTTTCGCGACGGCATGACCATTATGGTGGGCGGCTTTAT
GGGGGTAGGCACCCCGCCCCGCCTGATCTCGGCCCTGCTGGAGTCCGGCGTCAGGGACCTGACCCTGATCGCCAACGATA
CCGCCTTTGTCGATACGGGCATCGGCCCGCTGATCGTCAACGGGCGGGTCAGCCGCGTCATCGCCTCCCACATCGGCACC
AATCCGGAGACCGGGCGGCGCATGATGGCCGGGGAGATGGCGGTGCAACTGGTTCCGCAGGGCACCCTGATTGAACAGAT
CCGCTGCGGCGGCGCCGGGCTCGGCGGTTTTCTGACCCCCACCGGCGTCGGTACCGTCGTCGCCGAGGGCAAGCAGAGCC
TGACGCTCGACGGCAAAACCTGGCTGCTGGAGCGCCCGCTGCGCGCCGATCTGGCGCTGATCCGCGCCCATCGCGCCGAT
CCCCTGGGCAATCTGACCTACCAGCTCAGCGCCCGCAACTTTAACCCGCTGATTGCCCTCGCCGCCGACATCACCCTGGC
AGAGCCGGACGAACTGGTGGAGACCGGTGCGCTGCTGCCTGACCACATCGTGACGCCCGGCGCAGTCATCGACCATATCG
TCCTGCCTCAGGAGAATAAATAA

Upstream 100 bases:

>100_bases
TTCAATTGGTTATTCAATAATTTCATCTATAGGCCACGCTGGCATCCGGCTTGCTATTCCCTTTAGGTACCTAAATTAGC
GTACGTAACAGGGAAAAATA

Downstream 100 bases:

>100_bases
TGGATGCGAAACAGCGTATTGCGCGCCGCGTGGCGCGAGAGCTGCACGATGGCGACATCGTCAATCTGGGCATCGGCCTG
CCGACGATGGTCGCCAATTA

Product: acetyl-CoA:acetoacetyl-CoA transferase subunit alpha

Products: NA

Alternate protein names: Acetyl-CoA:acetoacetate-CoA transferase subunit alpha [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MKTKLITLQSATGLFRDGMTIMVGGFMGVGTPPRLISALLESGVRDLTLIANDTAFVDTGIGPLIVNGRVSRVIASHIGT
NPETGRRMMAGEMAVQLVPQGTLIEQIRCGGAGLGGFLTPTGVGTVVAEGKQSLTLDGKTWLLERPLRADLALIRAHRAD
PLGNLTYQLSARNFNPLIALAADITLAEPDELVETGALLPDHIVTPGAVIDHIVLPQENK

Sequences:

>Translated_220_residues
MKTKLITLQSATGLFRDGMTIMVGGFMGVGTPPRLISALLESGVRDLTLIANDTAFVDTGIGPLIVNGRVSRVIASHIGT
NPETGRRMMAGEMAVQLVPQGTLIEQIRCGGAGLGGFLTPTGVGTVVAEGKQSLTLDGKTWLLERPLRADLALIRAHRAD
PLGNLTYQLSARNFNPLIALAADITLAEPDELVETGALLPDHIVTPGAVIDHIVLPQENK
>Mature_220_residues
MKTKLITLQSATGLFRDGMTIMVGGFMGVGTPPRLISALLESGVRDLTLIANDTAFVDTGIGPLIVNGRVSRVIASHIGT
NPETGRRMMAGEMAVQLVPQGTLIEQIRCGGAGLGGFLTPTGVGTVVAEGKQSLTLDGKTWLLERPLRADLALIRAHRAD
PLGNLTYQLSARNFNPLIALAADITLAEPDELVETGALLPDHIVTPGAVIDHIVLPQENK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=216, Percent_Identity=37.962962962963, Blast_Score=161, Evalue=5e-40,
Organism=Homo sapiens, GI11545841, Length=222, Percent_Identity=39.1891891891892, Blast_Score=157, Evalue=9e-39,
Organism=Escherichia coli, GI1788551, Length=220, Percent_Identity=89.0909090909091, Blast_Score=397, Evalue=1e-112,
Organism=Escherichia coli, GI1787985, Length=243, Percent_Identity=24.2798353909465, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17531517, Length=241, Percent_Identity=32.7800829875519, Blast_Score=146, Evalue=8e-36,
Organism=Drosophila melanogaster, GI21358325, Length=216, Percent_Identity=43.5185185185185, Blast_Score=181, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24655794, Length=216, Percent_Identity=43.5185185185185, Blast_Score=181, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.8 [H]

Molecular weight: Translated: 23188; Mature: 23188

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKLITLQSATGLFRDGMTIMVGGFMGVGTPPRLISALLESGVRDLTLIANDTAFVDTG
CCCEEEEEECCCCHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCEEEECC
IGPLIVNGRVSRVIASHIGTNPETGRRMMAGEMAVQLVPQGTLIEQIRCGGAGLGGFLTP
CCEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHEEEECCCCHHHHHHHCCCCCCCCCCCC
TGVGTVVAEGKQSLTLDGKTWLLERPLRADLALIRAHRADPLGNLTYQLSARNFNPLIAL
CCCEEEEECCCCEEEECCCEEEECCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEE
AADITLAEPDELVETGALLPDHIVTPGAVIDHIVLPQENK
EECCEECCCHHHHHHCCCCCCCCCCCCHHHHEEECCCCCC
>Mature Secondary Structure
MKTKLITLQSATGLFRDGMTIMVGGFMGVGTPPRLISALLESGVRDLTLIANDTAFVDTG
CCCEEEEEECCCCHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCEEEECC
IGPLIVNGRVSRVIASHIGTNPETGRRMMAGEMAVQLVPQGTLIEQIRCGGAGLGGFLTP
CCEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHEEEECCCCHHHHHHHCCCCCCCCCCCC
TGVGTVVAEGKQSLTLDGKTWLLERPLRADLALIRAHRADPLGNLTYQLSARNFNPLIAL
CCCEEEEECCCCEEEECCCEEEECCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEE
AADITLAEPDELVETGALLPDHIVTPGAVIDHIVLPQENK
EECCEECCCHHHHHHCCCCCCCCCCCCHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]