Click here to switch to the map view.

The map label for this gene is pabB [H]

Identifier: 238919756

GI number: 238919756

Start: 1795831

End: 1797219

Strand: Reverse

Name: pabB [H]

Synonym: NT01EI_1860

Alternate gene names: 238919756

Gene position: 1797219-1795831 (Counterclockwise)

Preceding gene: 238919758

Following gene: 238919755

Centisome position: 47.14

GC content: 65.37

Gene sequence:

>1389_bases
ATGACCGCTATCCCCGAACTGACACAGCGTGACCTTCCCTACCGGCCCGATGCGGCGCTGCGCTACTTTACCCCGCTGGC
GCATCATCCCTGGGCCATGCTGCTCAGCTCCGCCGCCGCCGACCACGCCCATAACCGCTATGATATTGTCGTAGCCGACC
CCTGCGCCACGCTGCAGACCCGCGGCGAACAGACGCAGATCGCCACGCGGGATGGTGCCTGCCGTGACGACGGTGGCGAT
CCGCTGACCCTATTGCGCACAGAGATTGATCGCTATCTTCCCCGCTGCCCACCGCAGCCGGATCTGCCGTTTTGCGGGGG
GGCTCTCGGGCTGTGGGGCTACGATCTCGGGCGACGATTCGAACATCTGCCCAGCCAGGCCCACGCCGATCTGCAGGCCC
CGGACATGGCGCAGGGGATCTACGACTGGGCGCTGATCGTCGATCATCAGCGGCGTAGGGTGACGCTGCTCAGCTGGCAG
GACGCTGGGAAACGCCTGGCCTGGCTGCTGGCGCAGACGCCCGTCCCCGCCGCCCCCTTCAGCCTGACGTCTGCGTGGCA
GGCTAACCTGAGCCGACACGCGTACCGCCAAGCCTTCCAGCGGATACAGGCCCACTTACAGGCCGGCGACTGCTACCAAA
TCAACCTGACCCAGCGCTTCAGCGCCGACTACCGCGGCGATGAGTGGCAGGCCTTCCTGCGGCTGACCCAGGCCAACCGG
GCACCGTTTTCCGCCTTCCTGCGTCTACCGCACAGCGCCGTGATCAGCGTCTCACCGGAGCGTTTCCTGCAGCTCAGCCA
AGGCGATATCGTGACCCGCCCGATCAAAGGTACCCTGCCCCGATGCCCGATGCCCCATGACGATGCCCTGCAGCGCCTGC
GTCTGGCTGCCTCAGCCAAAGATCGCGCAGAGAACCTGATGATTGTCGATCTGATGCGCAACGACGTTGGCCGGATCGCC
GCGCCGGGCAGCGTCAGCGTACCCGAGCTGTTCGCGGTGGAAACCTTCCCCGCCGTTCACCATCTGGTCAGCACCGTCTG
CGCCCGTCTGGCCGAAGGGCTGGATGCCTGCGATCTGCTGCGCGCCTGCTTTCCGGGCGGATCGATTACCGGGGCACCCA
AGATCCGCGCCATGGAGATCATCGATACGCTGGAGCCACAACGGCGTAACCTTTACTGCGGATCCATTGGCTATATCAGT
GCCTGCGGCAATATGGACACCAGCATCACGATCCGTACCCTGCTGGCGGAGCATGGACGCCTGCACTGCTGGGCGGGCGG
CGGCATCGTCGCCGACAGCGAGGCAGAGGCCGAATATCAGGAGACGCTGGACAAAGTCAGCCGGATCCTGCCGCTGCTGG
CGGACGGAACACCTCTGCTATGCGACTGA

Upstream 100 bases:

>100_bases
ACCCGACGAACGGAACAGCACCGTGGTGATTGCCGCACAGGCGCCATCCGTAGATAATTGACCTAAATCATACACAGACC
GATGAGACTCCCGCGCCGCC

Downstream 100 bases:

>100_bases
GCCCAGCGTTGGCCCGCTTTGTAACCGATTTTCAGCTGAATAGCCCGCTGCCGGAGCGCCCGACGCGCCACACGCGCCAG
GCGGCGGTGCTGATCCCCAT

Product: para-aminobenzoate synthase, component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MTAIPELTQRDLPYRPDAALRYFTPLAHHPWAMLLSSAAADHAHNRYDIVVADPCATLQTRGEQTQIATRDGACRDDGGD
PLTLLRTEIDRYLPRCPPQPDLPFCGGALGLWGYDLGRRFEHLPSQAHADLQAPDMAQGIYDWALIVDHQRRRVTLLSWQ
DAGKRLAWLLAQTPVPAAPFSLTSAWQANLSRHAYRQAFQRIQAHLQAGDCYQINLTQRFSADYRGDEWQAFLRLTQANR
APFSAFLRLPHSAVISVSPERFLQLSQGDIVTRPIKGTLPRCPMPHDDALQRLRLAASAKDRAENLMIVDLMRNDVGRIA
APGSVSVPELFAVETFPAVHHLVSTVCARLAEGLDACDLLRACFPGGSITGAPKIRAMEIIDTLEPQRRNLYCGSIGYIS
ACGNMDTSITIRTLLAEHGRLHCWAGGGIVADSEAEAEYQETLDKVSRILPLLADGTPLLCD

Sequences:

>Translated_462_residues
MTAIPELTQRDLPYRPDAALRYFTPLAHHPWAMLLSSAAADHAHNRYDIVVADPCATLQTRGEQTQIATRDGACRDDGGD
PLTLLRTEIDRYLPRCPPQPDLPFCGGALGLWGYDLGRRFEHLPSQAHADLQAPDMAQGIYDWALIVDHQRRRVTLLSWQ
DAGKRLAWLLAQTPVPAAPFSLTSAWQANLSRHAYRQAFQRIQAHLQAGDCYQINLTQRFSADYRGDEWQAFLRLTQANR
APFSAFLRLPHSAVISVSPERFLQLSQGDIVTRPIKGTLPRCPMPHDDALQRLRLAASAKDRAENLMIVDLMRNDVGRIA
APGSVSVPELFAVETFPAVHHLVSTVCARLAEGLDACDLLRACFPGGSITGAPKIRAMEIIDTLEPQRRNLYCGSIGYIS
ACGNMDTSITIRTLLAEHGRLHCWAGGGIVADSEAEAEYQETLDKVSRILPLLADGTPLLCD
>Mature_461_residues
TAIPELTQRDLPYRPDAALRYFTPLAHHPWAMLLSSAAADHAHNRYDIVVADPCATLQTRGEQTQIATRDGACRDDGGDP
LTLLRTEIDRYLPRCPPQPDLPFCGGALGLWGYDLGRRFEHLPSQAHADLQAPDMAQGIYDWALIVDHQRRRVTLLSWQD
AGKRLAWLLAQTPVPAAPFSLTSAWQANLSRHAYRQAFQRIQAHLQAGDCYQINLTQRFSADYRGDEWQAFLRLTQANRA
PFSAFLRLPHSAVISVSPERFLQLSQGDIVTRPIKGTLPRCPMPHDDALQRLRLAASAKDRAENLMIVDLMRNDVGRIAA
PGSVSVPELFAVETFPAVHHLVSTVCARLAEGLDACDLLRACFPGGSITGAPKIRAMEIIDTLEPQRRNLYCGSIGYISA
CGNMDTSITIRTLLAEHGRLHCWAGGGIVADSEAEAEYQETLDKVSRILPLLADGTPLLCD

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=442, Percent_Identity=63.5746606334842, Blast_Score=567, Evalue=1e-163,
Organism=Escherichia coli, GI1787518, Length=367, Percent_Identity=33.5149863760218, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1786809, Length=205, Percent_Identity=28.780487804878, Blast_Score=72, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6320935, Length=439, Percent_Identity=30.5239179954442, Blast_Score=196, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6324361, Length=395, Percent_Identity=26.8354430379747, Blast_Score=137, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 51079; Mature: 50948

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIPELTQRDLPYRPDAALRYFTPLAHHPWAMLLSSAAADHAHNRYDIVVADPCATLQT
CCCCCCHHHCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHC
RGEQTQIATRDGACRDDGGDPLTLLRTEIDRYLPRCPPQPDLPFCGGALGLWGYDLGRRF
CCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
EHLPSQAHADLQAPDMAQGIYDWALIVDHQRRRVTLLSWQDAGKRLAWLLAQTPVPAAPF
HHCCCHHCCCCCCCHHHHHHHHHHHEEECCCCEEEEEECHHHHHHHHHHHHCCCCCCCCC
SLTSAWQANLSRHAYRQAFQRIQAHLQAGDCYQINLTQRFSADYRGDEWQAFLRLTQANR
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHCCC
APFSAFLRLPHSAVISVSPERFLQLSQGDIVTRPIKGTLPRCPMPHDDALQRLRLAASAK
CHHHHHHHCCCCEEEEECHHHHHEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
DRAENLMIVDLMRNDVGRIAAPGSVSVPELFAVETFPAVHHLVSTVCARLAEGLDACDLL
HHHCCEEEEEEHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RACFPGGSITGAPKIRAMEIIDTLEPQRRNLYCGSIGYISACGNMDTSITIRTLLAEHGR
HHHCCCCCCCCCCCHHHHHHHHHCCCHHCCEEECCCCCEEECCCCCCHHHHHHHHHHCCC
LHCWAGGGIVADSEAEAEYQETLDKVSRILPLLADGTPLLCD
EEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TAIPELTQRDLPYRPDAALRYFTPLAHHPWAMLLSSAAADHAHNRYDIVVADPCATLQT
CCCCCHHHCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHC
RGEQTQIATRDGACRDDGGDPLTLLRTEIDRYLPRCPPQPDLPFCGGALGLWGYDLGRRF
CCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
EHLPSQAHADLQAPDMAQGIYDWALIVDHQRRRVTLLSWQDAGKRLAWLLAQTPVPAAPF
HHCCCHHCCCCCCCHHHHHHHHHHHEEECCCCEEEEEECHHHHHHHHHHHHCCCCCCCCC
SLTSAWQANLSRHAYRQAFQRIQAHLQAGDCYQINLTQRFSADYRGDEWQAFLRLTQANR
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCHHHHHHHHHHCCC
APFSAFLRLPHSAVISVSPERFLQLSQGDIVTRPIKGTLPRCPMPHDDALQRLRLAASAK
CHHHHHHHCCCCEEEEECHHHHHEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
DRAENLMIVDLMRNDVGRIAAPGSVSVPELFAVETFPAVHHLVSTVCARLAEGLDACDLL
HHHCCEEEEEEHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RACFPGGSITGAPKIRAMEIIDTLEPQRRNLYCGSIGYISACGNMDTSITIRTLLAEHGR
HHHCCCCCCCCCCCHHHHHHHHHCCCHHCCEEECCCCCEEECCCCCCHHHHHHHHHHCCC
LHCWAGGGIVADSEAEAEYQETLDKVSRILPLLADGTPLLCD
EEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]