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The map label for this gene is kdgR [H]

Identifier: 238919630

GI number: 238919630

Start: 1685511

End: 1686299

Strand: Direct

Name: kdgR [H]

Synonym: NT01EI_1731

Alternate gene names: 238919630

Gene position: 1685511-1686299 (Clockwise)

Preceding gene: 238919628

Following gene: 238919634

Centisome position: 44.21

GC content: 57.03

Gene sequence:

>789_bases
ATGACAACCGAAATAGATAAGCAGCCCGACGCCGTCTCCTCTGTCCTTAAAGTTTTTGGCATTCTGCAGGCGCTGAGTGG
GGAGCGCGAAATCGGTATCACTGAGCTCTCCCAGCGTGTGCTGATGTCCAAGAGCACCGTCTACCGTTTTCTGCAGACCA
TGAAGTCGCTGGGCTATGTGGCACAGGACTGCGGAACAGAAAAGTATACCCTGACGCTGAAGCTGTTCGAACTGGGGGCC
CACGCGCTACAGAATGTGGATCTGATCCGCCTGGCGGACATTGAGATGCGTGAACTGTCGCGATTGACGAAAGAGACTAT
CCATCTGGGAGCGCTGGACGAAGACGGCATCGTATATATCCACAAGATTGACTCGATGTACAACCTGCGTATGTATTCCC
GTATCGGACGCCGTAATCCGCTGCATAGCACCGCCATCGGTAAGGTGCTCCTGGCCTGGCGCGATCGCGGTGAGGTCGGG
GCGCTGGTCAGCCAGATTGAATTTACCCGCAGTACTCCCCGGACCATTTCCGACGCCGCCCAGTTGATGCAGGTGCTGGA
GCAGGTGCGCGCCCAGGGATATGGCGAAGACAACGAGGAGCAGGAGGAGGGGCTACGTTGCATCGCCGTGCCGGTATTCG
ATCGTTTTGGGGTAGCCGCTGCGGGATTAAGCATTTCGTTCCCGACGCTGCGTTTTTCAGAGACGGCGAAACAGGAATAC
GTGGCGATGCTGCATAGGGCGGCGCGGCGGATCTCTGAACAGATGGGCTGCCACGACTATCCTTTCTGA

Upstream 100 bases:

>100_bases
TGGCGCCTGGTTGCAGCGATGTATCCGACTGTCATTCGGGGAGTGTTCCTACTATACTGAAACATAGGTTCGTTTTTTTT
GATAAAGGTAACCCGACGCC

Downstream 100 bases:

>100_bases
TCATGATGCTATTCAATGGACTACGCGTTAGCGGAGAGCCGAAAGCGCGCGGGGGCCATAGGCCCCCGCTGTCGTGCTAT
AGATCGCCGGGTGGGGATCA

Product: KdgR repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MTTEIDKQPDAVSSVLKVFGILQALSGEREIGITELSQRVLMSKSTVYRFLQTMKSLGYVAQDCGTEKYTLTLKLFELGA
HALQNVDLIRLADIEMRELSRLTKETIHLGALDEDGIVYIHKIDSMYNLRMYSRIGRRNPLHSTAIGKVLLAWRDRGEVG
ALVSQIEFTRSTPRTISDAAQLMQVLEQVRAQGYGEDNEEQEEGLRCIAVPVFDRFGVAAAGLSISFPTLRFSETAKQEY
VAMLHRAARRISEQMGCHDYPF

Sequences:

>Translated_262_residues
MTTEIDKQPDAVSSVLKVFGILQALSGEREIGITELSQRVLMSKSTVYRFLQTMKSLGYVAQDCGTEKYTLTLKLFELGA
HALQNVDLIRLADIEMRELSRLTKETIHLGALDEDGIVYIHKIDSMYNLRMYSRIGRRNPLHSTAIGKVLLAWRDRGEVG
ALVSQIEFTRSTPRTISDAAQLMQVLEQVRAQGYGEDNEEQEEGLRCIAVPVFDRFGVAAAGLSISFPTLRFSETAKQEY
VAMLHRAARRISEQMGCHDYPF
>Mature_261_residues
TTEIDKQPDAVSSVLKVFGILQALSGEREIGITELSQRVLMSKSTVYRFLQTMKSLGYVAQDCGTEKYTLTLKLFELGAH
ALQNVDLIRLADIEMRELSRLTKETIHLGALDEDGIVYIHKIDSMYNLRMYSRIGRRNPLHSTAIGKVLLAWRDRGEVGA
LVSQIEFTRSTPRTISDAAQLMQVLEQVRAQGYGEDNEEQEEGLRCIAVPVFDRFGVAAAGLSISFPTLRFSETAKQEYV
AMLHRAARRISEQMGCHDYPF

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=261, Percent_Identity=81.6091954022989, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI1786468, Length=232, Percent_Identity=40.5172413793103, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI1786715, Length=229, Percent_Identity=30.5676855895196, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789999, Length=254, Percent_Identity=30.3149606299213, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790752, Length=223, Percent_Identity=30.0448430493274, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI87082359, Length=228, Percent_Identity=29.3859649122807, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788581, Length=221, Percent_Identity=30.7692307692308, Blast_Score=107, Evalue=7e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29508; Mature: 29377

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTEIDKQPDAVSSVLKVFGILQALSGEREIGITELSQRVLMSKSTVYRFLQTMKSLGYV
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQDCGTEKYTLTLKLFELGAHALQNVDLIRLADIEMRELSRLTKETIHLGALDEDGIVYI
HHHCCCCEEEEEEHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCEEEE
HKIDSMYNLRMYSRIGRRNPLHSTAIGKVLLAWRDRGEVGALVSQIEFTRSTPRTISDAA
EECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHH
QLMQVLEQVRAQGYGEDNEEQEEGLRCIAVPVFDRFGVAAAGLSISFPTLRFSETAKQEY
HHHHHHHHHHHCCCCCCCCHHHCCCEEEEEHHHHHHHHHHHCCEEECCCCHHHHHHHHHH
VAMLHRAARRISEQMGCHDYPF
HHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TTEIDKQPDAVSSVLKVFGILQALSGEREIGITELSQRVLMSKSTVYRFLQTMKSLGYV
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQDCGTEKYTLTLKLFELGAHALQNVDLIRLADIEMRELSRLTKETIHLGALDEDGIVYI
HHHCCCCEEEEEEHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCEEEE
HKIDSMYNLRMYSRIGRRNPLHSTAIGKVLLAWRDRGEVGALVSQIEFTRSTPRTISDAA
EECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHH
QLMQVLEQVRAQGYGEDNEEQEEGLRCIAVPVFDRFGVAAAGLSISFPTLRFSETAKQEY
HHHHHHHHHHHCCCCCCCCHHHCCCEEEEEHHHHHHHHHHHCCEEECCCCHHHHHHHHHH
VAMLHRAARRISEQMGCHDYPF
HHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]