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The map label for this gene is pgl [H]

Identifier: 238919512

GI number: 238919512

Start: 1571005

End: 1571700

Strand: Direct

Name: pgl [H]

Synonym: NT01EI_1608

Alternate gene names: 238919512

Gene position: 1571005-1571700 (Clockwise)

Preceding gene: 238919511

Following gene: 238919513

Centisome position: 41.21

GC content: 65.95

Gene sequence:

>696_bases
ATGGCACACCTTATCGAATTTGGCAGCGCGGACGCGCTGAACATCCACCTGGCAGAGGCTGTCGCCGAGCGCCTGCGTCA
GGGGATCGCCGCCTGCGGGCAGGCCAGCCTGGTGGTCTCCGGTGGACGCACCCCGCTGGGTCTGTTTGCGGTGCTGCGTG
AGCAAGCGCTCGAGTGGTCACGGGTCTGGGTGACCCTGGCGGACGAACGCTGGGTCGGGACAGACGATGACGCCAGCAAC
GAGCAGCTGGTACGGGCGAACCTGTTACAGGGGCCGGCGGCGGCGGCGCGTTTTATTGGCCTGAAGAATGACGCGGCGAC
CCCCTTTGATGGTGCGCAAGCCGCAGAGGCGGCGCTGGCGGTAATGGCGCGTCCCTTTGACGCGCTGATCCTGGGTATGG
GGGACGACGGCCATACCGCATCACTTTTCCCCGGGGCAGAGAATCTGTTCCCGGCTCTCGCGATGGACTCCGGACGCGTG
TGTATGGGGATGACCCCGCTCACGGCGCCGCTCGATCGCATCACCCTCACACTCCCGGCCCTGCTGGACAGCCGTCATAT
TTACCTGCACCTGGTGGGCAACGCCAAACGCAGGGTATATGAGCAGGCCGCCGGCGGAGCGGAGGTGAATGAGATGCCGA
TCCGCGCCGTGCTCCAGCAGAGCATGACGCCGGTCGACGTCTACTGGACGGCATGA

Upstream 100 bases:

>100_bases
GGTGGCGCTGATCACCCGCGACGGCCGTTGCTGGAACGAATTCTGAGTGGACTGTGCGGGGTGCAGGCCGCCCCGCGCAA
CGCGAGAGGAGCAGATATAA

Downstream 100 bases:

>100_bases
GGCTGTAATGAATCCAATCGTAGAACGTGTTACCCAACGCATTATTGAACGCTCCCGCGCCACTCGTGTGGCGTATCTGG
CTAAGATTGAGCGGGCGCGC

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MAHLIEFGSADALNIHLAEAVAERLRQGIAACGQASLVVSGGRTPLGLFAVLREQALEWSRVWVTLADERWVGTDDDASN
EQLVRANLLQGPAAAARFIGLKNDAATPFDGAQAAEAALAVMARPFDALILGMGDDGHTASLFPGAENLFPALAMDSGRV
CMGMTPLTAPLDRITLTLPALLDSRHIYLHLVGNAKRRVYEQAAGGAEVNEMPIRAVLQQSMTPVDVYWTA

Sequences:

>Translated_231_residues
MAHLIEFGSADALNIHLAEAVAERLRQGIAACGQASLVVSGGRTPLGLFAVLREQALEWSRVWVTLADERWVGTDDDASN
EQLVRANLLQGPAAAARFIGLKNDAATPFDGAQAAEAALAVMARPFDALILGMGDDGHTASLFPGAENLFPALAMDSGRV
CMGMTPLTAPLDRITLTLPALLDSRHIYLHLVGNAKRRVYEQAAGGAEVNEMPIRAVLQQSMTPVDVYWTA
>Mature_230_residues
AHLIEFGSADALNIHLAEAVAERLRQGIAACGQASLVVSGGRTPLGLFAVLREQALEWSRVWVTLADERWVGTDDDASNE
QLVRANLLQGPAAAARFIGLKNDAATPFDGAQAAEAALAVMARPFDALILGMGDDGHTASLFPGAENLFPALAMDSGRVC
MGMTPLTAPLDRITLTLPALLDSRHIYLHLVGNAKRRVYEQAAGGAEVNEMPIRAVLQQSMTPVDVYWTA

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=205, Percent_Identity=31.219512195122, Blast_Score=78, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6321687, Length=247, Percent_Identity=25.1012145748988, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321957, Length=205, Percent_Identity=25.8536585365854, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24641119, Length=204, Percent_Identity=30.3921568627451, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 24600; Mature: 24469

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHLIEFGSADALNIHLAEAVAERLRQGIAACGQASLVVSGGRTPLGLFAVLREQALEWS
CCCEEECCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCEE
RVWVTLADERWVGTDDDASNEQLVRANLLQGPAAAARFIGLKNDAATPFDGAQAAEAALA
EEEEEEECCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHEECCCCCCCCCCCHHHHHHHHH
VMARPFDALILGMGDDGHTASLFPGAENLFPALAMDSGRVCMGMTPLTAPLDRITLTLPA
HHHCCCEEEEEECCCCCCEEEECCCHHHHHHHEECCCCCEEECCCCCCCCHHHHEEEHHH
LLDSRHIYLHLVGNAKRRVYEQAAGGAEVNEMPIRAVLQQSMTPVDVYWTA
HHCCCEEEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEC
>Mature Secondary Structure 
AHLIEFGSADALNIHLAEAVAERLRQGIAACGQASLVVSGGRTPLGLFAVLREQALEWS
CCEEECCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCEE
RVWVTLADERWVGTDDDASNEQLVRANLLQGPAAAARFIGLKNDAATPFDGAQAAEAALA
EEEEEEECCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHEECCCCCCCCCCCHHHHHHHHH
VMARPFDALILGMGDDGHTASLFPGAENLFPALAMDSGRVCMGMTPLTAPLDRITLTLPA
HHHCCCEEEEEECCCCCCEEEECCCHHHHHHHEECCCCCEEECCCCCCCCHHHHEEEHHH
LLDSRHIYLHLVGNAKRRVYEQAAGGAEVNEMPIRAVLQQSMTPVDVYWTA
HHCCCEEEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA