Click here to switch to the map view.

The map label for this gene is msbB1 [H]

Identifier: 238919508

GI number: 238919508

Start: 1565369

End: 1566331

Strand: Direct

Name: msbB1 [H]

Synonym: NT01EI_1604

Alternate gene names: 238919508

Gene position: 1565369-1566331 (Clockwise)

Preceding gene: 238919507

Following gene: 238919511

Centisome position: 41.06

GC content: 58.26

Gene sequence:

>963_bases
ATGCAACAAGAGACCAAATCAACTCCTGAGTTCATTCCGCACTTTCGTGCCGCGTTCCTCTCGCCCCGTTACTGGGGCGT
CTGGTTGGGGATAGCGCTGATGGCGGCGATGGCATTCCTGCCGCTGCGCCTGCGCGATTGGATGATCGGCGCCGTCGGGC
GTCTGGCCGGGCGTCTGGCCAGTGGCGCCCGTCGCCGCGCACAAATTAACCTGATGCTCTGCTTCCCGCAGATGGCGGCG
CGTCGGCGTGAGGCGATCATTGATACGATGTTCGCCCGCGCGGGGCAGTCCATGTTTCTGATGGCCGAACTGACCCTACG
CGGCCCGCAGCGCTTGCTGCGTCATACCCATTGGCACGGCGGGGAGATCATTGAGCAGGCGCGTGAACAGGGGGATAACG
TGATTTTTTTGGTGCCTCATGGCTGGGCCGTCGATATTCCCGCCATGCTGTTGGCCGCCGGTGGACAGCCGATGGCCGCC
ATGTTTCATAATCAGAAGAACCCGCTGGTTGACTATCTGTGGAACCGTGCGCGACGCCGTTTTGGTGGCCGCCTGCATGC
ACGTAACGATGGCATCAAACCGTTTATCAGTTCGGTACGTAAAGGCTACTGGGGGTATTATCTGCCCGATCAGGATCACG
GCGCAGAGCATAGTGAGTTTGTGGATTTTTTCGCCACCTATAAGGCCACGCTACCTGCCATCGGGCGACTGATGAAGCTG
TGTCGGGCGCGTATTATTCCGCTGTTTCCGGTGTATGATGGGGATAAAGGGCGGCTGGACATCTATCTTCGTCCATCGAT
GGACGATATTGCAGGACAGGATGACGATTACATTGCCCGGAGGATGAATCAGGAAGTGGAACTGCTGATGGGGGAACACC
CGGAGCAGTACACCTGGATCCTGAAGCTGTTGAAAACGCGCAGGCCGGGAGAGATAGAGCCCTATTGCCGCCAGGATTTA
TGA

Upstream 100 bases:

>100_bases
CCCATCCGGGGCAGGGGCAGTTTTTTTTTGTCTGCCAAATGGCTACAATTTCCAGCCATCCCATTCGTAATCCGAGTGGG
GATCACACAAGAGCCCACTG

Downstream 100 bases:

>100_bases
TGCGGTGCGGCTGAGCGCAGGCCAGTGATTTAAGAGAATAGAATGGGCCTTGGCGTTCTTGCGCTGCTCTGCGTGTATGG
GGCCGGCCAGCTTGTTCTTC

Product: lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MQQETKSTPEFIPHFRAAFLSPRYWGVWLGIALMAAMAFLPLRLRDWMIGAVGRLAGRLASGARRRAQINLMLCFPQMAA
RRREAIIDTMFARAGQSMFLMAELTLRGPQRLLRHTHWHGGEIIEQAREQGDNVIFLVPHGWAVDIPAMLLAAGGQPMAA
MFHNQKNPLVDYLWNRARRRFGGRLHARNDGIKPFISSVRKGYWGYYLPDQDHGAEHSEFVDFFATYKATLPAIGRLMKL
CRARIIPLFPVYDGDKGRLDIYLRPSMDDIAGQDDDYIARRMNQEVELLMGEHPEQYTWILKLLKTRRPGEIEPYCRQDL

Sequences:

>Translated_320_residues
MQQETKSTPEFIPHFRAAFLSPRYWGVWLGIALMAAMAFLPLRLRDWMIGAVGRLAGRLASGARRRAQINLMLCFPQMAA
RRREAIIDTMFARAGQSMFLMAELTLRGPQRLLRHTHWHGGEIIEQAREQGDNVIFLVPHGWAVDIPAMLLAAGGQPMAA
MFHNQKNPLVDYLWNRARRRFGGRLHARNDGIKPFISSVRKGYWGYYLPDQDHGAEHSEFVDFFATYKATLPAIGRLMKL
CRARIIPLFPVYDGDKGRLDIYLRPSMDDIAGQDDDYIARRMNQEVELLMGEHPEQYTWILKLLKTRRPGEIEPYCRQDL
>Mature_320_residues
MQQETKSTPEFIPHFRAAFLSPRYWGVWLGIALMAAMAFLPLRLRDWMIGAVGRLAGRLASGARRRAQINLMLCFPQMAA
RRREAIIDTMFARAGQSMFLMAELTLRGPQRLLRHTHWHGGEIIEQAREQGDNVIFLVPHGWAVDIPAMLLAAGGQPMAA
MFHNQKNPLVDYLWNRARRRFGGRLHARNDGIKPFISSVRKGYWGYYLPDQDHGAEHSEFVDFFATYKATLPAIGRLMKL
CRARIIPLFPVYDGDKGRLDIYLRPSMDDIAGQDDDYIARRMNQEVELLMGEHPEQYTWILKLLKTRRPGEIEPYCRQDL

Specific function: Transfers myristate or laurate, activated on ACP, to (KDO)2-(lauroyl)-lipid IVA [H]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI1788161, Length=318, Percent_Identity=66.0377358490566, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI1787292, Length=303, Percent_Identity=29.042904290429, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI87082094, Length=302, Percent_Identity=27.1523178807947, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011921 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 36866; Mature: 36866

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQETKSTPEFIPHFRAAFLSPRYWGVWLGIALMAAMAFLPLRLRDWMIGAVGRLAGRLA
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGARRRAQINLMLCFPQMAARRREAIIDTMFARAGQSMFLMAELTLRGPQRLLRHTHWHG
HHHHHHEEEEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCHHHHHHHCCCCC
GEIIEQAREQGDNVIFLVPHGWAVDIPAMLLAAGGQPMAAMFHNQKNPLVDYLWNRARRR
HHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHH
FGGRLHARNDGIKPFISSVRKGYWGYYLPDQDHGAEHSEFVDFFATYKATLPAIGRLMKL
HCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
CRARIIPLFPVYDGDKGRLDIYLRPSMDDIAGQDDDYIARRMNQEVELLMGEHPEQYTWI
HHHHCCEEEEEECCCCCEEEEEECCCCHHHCCCCHHHHHHHHCHHHHHHHCCCCHHHHHH
LKLLKTRRPGEIEPYCRQDL
HHHHHCCCCCCCCCHHCCCC
>Mature Secondary Structure
MQQETKSTPEFIPHFRAAFLSPRYWGVWLGIALMAAMAFLPLRLRDWMIGAVGRLAGRLA
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGARRRAQINLMLCFPQMAARRREAIIDTMFARAGQSMFLMAELTLRGPQRLLRHTHWHG
HHHHHHEEEEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCHHHHHHHCCCCC
GEIIEQAREQGDNVIFLVPHGWAVDIPAMLLAAGGQPMAAMFHNQKNPLVDYLWNRARRR
HHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHH
FGGRLHARNDGIKPFISSVRKGYWGYYLPDQDHGAEHSEFVDFFATYKATLPAIGRLMKL
HCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
CRARIIPLFPVYDGDKGRLDIYLRPSMDDIAGQDDDYIARRMNQEVELLMGEHPEQYTWI
HHHHCCEEEEEECCCCCEEEEEECCCCHHHCCCCHHHHHHHHCHHHHHHHCCCCHHHHHH
LKLLKTRRPGEIEPYCRQDL
HHHHHCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12384590; 12704152 [H]