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The map label for this gene is ruvB

Identifier: 238919503

GI number: 238919503

Start: 1560129

End: 1561133

Strand: Direct

Name: ruvB

Synonym: NT01EI_1599

Alternate gene names: 238919503

Gene position: 1560129-1561133 (Clockwise)

Preceding gene: 238919502

Following gene: 238919506

Centisome position: 40.92

GC content: 62.49

Gene sequence:

>1005_bases
ATGATAGAAGCCGATCGTCTGATTGCCGCCGATGCCCAGAGTGAGGAGGAGTTCCTCGATCGCGCCATTCGGCCGAAGAC
ACTGGCCGACTACGTTGGCCAGCCGCAGGTGCGCGGGCAGATGGAGATTTTTATTAAGGCGGCCAAGCTGCGCGGTGATG
CGCTGGATCACCTGCTGATCTTCGGGCCGCCGGGGCTGGGGAAAACCACGCTGGCCAACATCGTCGCCAATGAGATGGGG
GTCAATCTGCGCACCACCTCGGGGCCCGTGTTGGAGAAGGCGGGCGATCTGGCGGCCATGCTGACCAATCTGGAGCCGCA
CGATGTGCTGTTCATCGATGAGATCCATCGCTTGTCGCCGGTGGTGGAAGAGGTGCTCTACCCGGCAATGGAAGACTATC
AGCTGGATATTATGATCGGCGAGGGGCCGGCGGCGCGCTCGATCAAGATCGACCTGCCGCCTTTTACGCTGGTCGGTGCG
ACCACCCGCGCCGGATCGCTGACCTCACCGCTGCGTGACCGCTTTGGCATCGTGCAGCGGCTGGAGTTTTATCAGGTGGC
CGATCTACAGCATATCGTCGGGCGTAGCGCCCACTGCCTGGGGCTGGCGCTGACGGATGAAGGCGCGCTGGAGGTGGCAC
GTCGCTCGCGCGGTACGCCGCGTATTGCCAACCGTCTGCTGCGCCGGGTGCGCGATTTTGCCGAGGTGTGCGCCGACGGG
CGAATTGACGGTGAGGTGGCTGCGCAGGCACTGAATATGCTGGATGTGGATGCCGCAGGCTTTGACTATATGGATCGCAA
GCTGCTGTTGGCGGTGATCGATAAGTTTATGGGGGGGCCGGTCGGGCTGGATAACCTGGCGGCGGCGATTGGCGAGGAGC
GCGAGACCATTGAGGATGTGCTGGAGCCGTATCTGATCCAGCAGGGGTTCATTCAGCGTACGCCGCGTGGGCGTATCGCG
ACTGTCCATGCCTACCAACACTTCGGCATCGATCGCGCAGAGTAG

Upstream 100 bases:

>100_bases
AGTCGCTTGGTGAACCGGGTGGCGGTGGCCGGTGCTGACAGTGAAACCCTGATCCGCGACGCGCTGCGCGCTGCGCTGTA
ATAACCCAGGAGAGCACGGG

Downstream 100 bases:

>100_bases
GAGCCGCTGTAAAAAAACCCGTTGCCGCGACGTCGGCTACGGGGTTTTTTTATGCGCGGTACGGCGGTCTAGGTGCTTTG
GCGCCGTCCCAGACTGAGGA

Product: holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MIEADRLIAADAQSEEEFLDRAIRPKTLADYVGQPQVRGQMEIFIKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMG
VNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLVGA
TTRAGSLTSPLRDRFGIVQRLEFYQVADLQHIVGRSAHCLGLALTDEGALEVARRSRGTPRIANRLLRRVRDFAEVCADG
RIDGEVAAQALNMLDVDAAGFDYMDRKLLLAVIDKFMGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFIQRTPRGRIA
TVHAYQHFGIDRAE

Sequences:

>Translated_334_residues
MIEADRLIAADAQSEEEFLDRAIRPKTLADYVGQPQVRGQMEIFIKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMG
VNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLVGA
TTRAGSLTSPLRDRFGIVQRLEFYQVADLQHIVGRSAHCLGLALTDEGALEVARRSRGTPRIANRLLRRVRDFAEVCADG
RIDGEVAAQALNMLDVDAAGFDYMDRKLLLAVIDKFMGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFIQRTPRGRIA
TVHAYQHFGIDRAE
>Mature_334_residues
MIEADRLIAADAQSEEEFLDRAIRPKTLADYVGQPQVRGQMEIFIKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMG
VNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLVGA
TTRAGSLTSPLRDRFGIVQRLEFYQVADLQHIVGRSAHCLGLALTDEGALEVARRSRGTPRIANRLLRRVRDFAEVCADG
RIDGEVAAQALNMLDVDAAGFDYMDRKLLLAVIDKFMGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFIQRTPRGRIA
TVHAYQHFGIDRAE

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=334, Percent_Identity=86.5269461077844, Blast_Score=580, Evalue=1e-167,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_EDWI9 (C5B9T2)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002933018.1
- GeneID:   7961927
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_1599
- OMA:   EKFDGGP
- ProtClustDB:   CLSK2813096
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 36675; Mature: 36675

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEADRLIAADAQSEEEFLDRAIRPKTLADYVGQPQVRGQMEIFIKAAKLRGDALDHLLI
CCCCCCEEECCCCCHHHHHHHHCCCHHHHHHCCCCCCCCHHHHEEEHHHHCCCCCCEEEE
FGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSP
ECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHH
VVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLVGATTRAGSLTSPLRDRFGIVQR
HHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHH
LEFYQVADLQHIVGRSAHCLGLALTDEGALEVARRSRGTPRIANRLLRRVRDFAEVCADG
HHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
RIDGEVAAQALNMLDVDAAGFDYMDRKLLLAVIDKFMGGPVGLDNLAAAIGEERETIEDV
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHH
LEPYLIQQGFIQRTPRGRIATVHAYQHFGIDRAE
HHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCCCC
>Mature Secondary Structure
MIEADRLIAADAQSEEEFLDRAIRPKTLADYVGQPQVRGQMEIFIKAAKLRGDALDHLLI
CCCCCCEEECCCCCHHHHHHHHCCCHHHHHHCCCCCCCCHHHHEEEHHHHCCCCCCEEEE
FGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSP
ECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHH
VVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLVGATTRAGSLTSPLRDRFGIVQR
HHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHH
LEFYQVADLQHIVGRSAHCLGLALTDEGALEVARRSRGTPRIANRLLRRVRDFAEVCADG
HHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
RIDGEVAAQALNMLDVDAAGFDYMDRKLLLAVIDKFMGGPVGLDNLAAAIGEERETIEDV
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHH
LEPYLIQQGFIQRTPRGRIATVHAYQHFGIDRAE
HHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA