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The map label for this gene is appA [H]

Identifier: 238919349

GI number: 238919349

Start: 1418892

End: 1420226

Strand: Direct

Name: appA [H]

Synonym: NT01EI_1443

Alternate gene names: 238919349

Gene position: 1418892-1420226 (Clockwise)

Preceding gene: 238919346

Following gene: 238919350

Centisome position: 37.22

GC content: 67.27

Gene sequence:

>1335_bases
ATGCGCTGGTGCGAGCTGAGCCGTTGGTTATTCCCCGTATCGCTTACGCTGTTATTTCCCCTGCCGCTGAAGGCGGCGGA
GGCAGCGCACCCTGTACGCCATCTGGAGAGGGTGGTGATCGTCAGCCGCCACGGCGTACGGGCGCCGACCAAAATGCCGG
CGCTGATCCGTGAGGTCACCCCGGATGGGTGGCCGGTATGGCCGGTGCCACTGGGTGATCTTACGCCGCGCGGAGCGTCC
CTGGTGACCCTGCTCGGCGCCTATTATCGGCAGCAGTTGAGCCGTGAGGGGCTGCTGCCCGCACAGGGGTGTCCCCCGGC
AGGGTGGGTCTATGCCTGGACCGATGTGGATCAGCGTACGCGTAAAACCGGCGCGGCTTTTCTGCAGGGATTGGCACCGG
GCTGTGCTGTCGCCATCCATCACCGGCCTGATGTGTCTCAGCGCGATCCCCTGTTTCATCCGGTCAAGGCGGGCCTCTGT
CGACTGGATAAGGCCCGCACGCGCCGGGCGATTGAAGCGCAGGCCGGTATGCCGCTGGCCGCGCTCAATCACCGTTATGG
CACCGCGCTGGCGCAGATGGCGCGGGTGCTGCATTTCGCGTCGTCGCCCTATTGCCAGCGGCGCAGCGGCGATGGGGTGT
GTACCCTCGCCCGGACCATGCCAACCCGGCTGCACATGGACGCTCACGGCGCCATCGCGCTGCGCGGCGCTCTGGGCCTC
TCTGCGACGCTGGCGGAGATGTTTCTGTTGCAGCAGGCGCAGGGAATGGCGCAGCCGGCCTGGGGGCGTATCGCCACCCC
GGCGCAGTGGCGGTCGTTGCTCCAGCTGCATAACCTTCAGTTTGATCTGCTGTCGCGTACCGACTATATCGCCCGTCATC
GCGGGACGCCGCTGATGTATACCGTGCTGCAGGCGCTGCACGGGCAGACGCCGCGCCTGCCGGGATTAACGGCGCAGAAC
CGCCTGCTGCTGCTGGTCGGCCATGATACCAATCTGGCCAATCTGTCCGGCCTGCTGCAAACGCCGTGGAGCCTGCCCGG
ACAGCCGGATAATACGCCGCCCGGCGGCGAACTGCGTTTTGAGCGTTGGCGCGACAGCACGGGTCGCGCCTGGGTGCGGG
TGAGCGTGGTCTACCAGTCGCTGGCGCAGCTGCGCCGGCAGAGCCGCCTGACGCTGCCGCTGCCGCCGCATCAGATGACC
CTGGCGTTGCCGGGATGCCGGGGGGAGATGGCGGATGGCCTCTGTCCACTGGATGCCTTCAGCCAGTGGCTCTCCTCCCG
CCTGATCCCGGCGTGTCTGCCGGTGCCCGACGGCGCGACAAACGCAATGGAGTAA

Upstream 100 bases:

>100_bases
TTTTTACCGCCCGGGCGGAATAATCGGACGGTGGGATTTACACTGAATCAAATAGGCCAGCATGGCCAAATCTTGTCGAA
ATTATGCCTTGGAGGCAAAA

Downstream 100 bases:

>100_bases
GCCCGGCCCGCCGTCCGGCAGCGGCGGCGCCCTCCCGCGGTGGTTTGGCGCCCCCCTTTCCGCAGTACCCGGTGCACCGC
CTGCCGTGCCGCTTTTTCCA

Product: phosphoanhydride phosphorylase

Products: NA

Alternate protein names: Phosphoanhydride phosphohydrolase; pH 2.5 acid phosphatase; AP; 4-phytase [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MRWCELSRWLFPVSLTLLFPLPLKAAEAAHPVRHLERVVIVSRHGVRAPTKMPALIREVTPDGWPVWPVPLGDLTPRGAS
LVTLLGAYYRQQLSREGLLPAQGCPPAGWVYAWTDVDQRTRKTGAAFLQGLAPGCAVAIHHRPDVSQRDPLFHPVKAGLC
RLDKARTRRAIEAQAGMPLAALNHRYGTALAQMARVLHFASSPYCQRRSGDGVCTLARTMPTRLHMDAHGAIALRGALGL
SATLAEMFLLQQAQGMAQPAWGRIATPAQWRSLLQLHNLQFDLLSRTDYIARHRGTPLMYTVLQALHGQTPRLPGLTAQN
RLLLLVGHDTNLANLSGLLQTPWSLPGQPDNTPPGGELRFERWRDSTGRAWVRVSVVYQSLAQLRRQSRLTLPLPPHQMT
LALPGCRGEMADGLCPLDAFSQWLSSRLIPACLPVPDGATNAME

Sequences:

>Translated_444_residues
MRWCELSRWLFPVSLTLLFPLPLKAAEAAHPVRHLERVVIVSRHGVRAPTKMPALIREVTPDGWPVWPVPLGDLTPRGAS
LVTLLGAYYRQQLSREGLLPAQGCPPAGWVYAWTDVDQRTRKTGAAFLQGLAPGCAVAIHHRPDVSQRDPLFHPVKAGLC
RLDKARTRRAIEAQAGMPLAALNHRYGTALAQMARVLHFASSPYCQRRSGDGVCTLARTMPTRLHMDAHGAIALRGALGL
SATLAEMFLLQQAQGMAQPAWGRIATPAQWRSLLQLHNLQFDLLSRTDYIARHRGTPLMYTVLQALHGQTPRLPGLTAQN
RLLLLVGHDTNLANLSGLLQTPWSLPGQPDNTPPGGELRFERWRDSTGRAWVRVSVVYQSLAQLRRQSRLTLPLPPHQMT
LALPGCRGEMADGLCPLDAFSQWLSSRLIPACLPVPDGATNAME
>Mature_444_residues
MRWCELSRWLFPVSLTLLFPLPLKAAEAAHPVRHLERVVIVSRHGVRAPTKMPALIREVTPDGWPVWPVPLGDLTPRGAS
LVTLLGAYYRQQLSREGLLPAQGCPPAGWVYAWTDVDQRTRKTGAAFLQGLAPGCAVAIHHRPDVSQRDPLFHPVKAGLC
RLDKARTRRAIEAQAGMPLAALNHRYGTALAQMARVLHFASSPYCQRRSGDGVCTLARTMPTRLHMDAHGAIALRGALGL
SATLAEMFLLQQAQGMAQPAWGRIATPAQWRSLLQLHNLQFDLLSRTDYIARHRGTPLMYTVLQALHGQTPRLPGLTAQN
RLLLLVGHDTNLANLSGLLQTPWSLPGQPDNTPPGGELRFERWRDSTGRAWVRVSVVYQSLAQLRRQSRLTLPLPPHQMT
LALPGCRGEMADGLCPLDAFSQWLSSRLIPACLPVPDGATNAME

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histidine acid phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1787215, Length=423, Percent_Identity=49.645390070922, Blast_Score=401, Evalue=1e-113,
Organism=Escherichia coli, GI1787237, Length=398, Percent_Identity=32.4120603015075, Blast_Score=216, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000560 [H]

Pfam domain/function: PF00328 Acid_phosphat_A [H]

EC number: =3.1.3.2; =3.1.3.26 [H]

Molecular weight: Translated: 48928; Mature: 48928

Theoretical pI: Translated: 10.67; Mature: 10.67

Prosite motif: PS00616 HIS_ACID_PHOSPHAT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWCELSRWLFPVSLTLLFPLPLKAAEAAHPVRHLERVVIVSRHGVRAPTKMPALIREVT
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHCC
PDGWPVWPVPLGDLTPRGASLVTLLGAYYRQQLSREGLLPAQGCPPAGWVYAWTDVDQRT
CCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHH
RKTGAAFLQGLAPGCAVAIHHRPDVSQRDPLFHPVKAGLCRLDKARTRRAIEAQAGMPLA
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
ALNHRYGTALAQMARVLHFASSPYCQRRSGDGVCTLARTMPTRLHMDAHGAIALRGALGL
HHCCHHHHHHHHHHHHHHHHCCCCHHCCCCCCEEEEHHHCCCEEEECCCCCEEEECHHCH
SATLAEMFLLQQAQGMAQPAWGRIATPAQWRSLLQLHNLQFDLLSRTDYIARHRGTPLMY
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHH
TVLQALHGQTPRLPGLTAQNRLLLLVGHDTNLANLSGLLQTPWSLPGQPDNTPPGGELRF
HHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEH
ERWRDSTGRAWVRVSVVYQSLAQLRRQSRLTLPLPPHQMTLALPGCRGEMADGLCPLDAF
HHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHCCCCCHHHH
SQWLSSRLIPACLPVPDGATNAME
HHHHHHCCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MRWCELSRWLFPVSLTLLFPLPLKAAEAAHPVRHLERVVIVSRHGVRAPTKMPALIREVT
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHCC
PDGWPVWPVPLGDLTPRGASLVTLLGAYYRQQLSREGLLPAQGCPPAGWVYAWTDVDQRT
CCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHH
RKTGAAFLQGLAPGCAVAIHHRPDVSQRDPLFHPVKAGLCRLDKARTRRAIEAQAGMPLA
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
ALNHRYGTALAQMARVLHFASSPYCQRRSGDGVCTLARTMPTRLHMDAHGAIALRGALGL
HHCCHHHHHHHHHHHHHHHHCCCCHHCCCCCCEEEEHHHCCCEEEECCCCCEEEECHHCH
SATLAEMFLLQQAQGMAQPAWGRIATPAQWRSLLQLHNLQFDLLSRTDYIARHRGTPLMY
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHH
TVLQALHGQTPRLPGLTAQNRLLLLVGHDTNLANLSGLLQTPWSLPGQPDNTPPGGELRF
HHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEH
ERWRDSTGRAWVRVSVVYQSLAQLRRQSRLTLPLPPHQMTLALPGCRGEMADGLCPLDAF
HHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHCCCCCHHHH
SQWLSSRLIPACLPVPDGATNAME
HHHHHHCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2168385; 8905232; 9278503; 3038201; 1658595; 8387749; 10696472; 1429631; 10655611 [H]