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The map label for this gene is mntH [H]

Identifier: 238919184

GI number: 238919184

Start: 1248697

End: 1249869

Strand: Direct

Name: mntH [H]

Synonym: NT01EI_1268

Alternate gene names: 238919184

Gene position: 1248697-1249869 (Clockwise)

Preceding gene: 238919180

Following gene: 238919186

Centisome position: 32.75

GC content: 60.87

Gene sequence:

>1173_bases
ATGGGGCCTGCCTTTATTGCCGCCATTGGTTATATCGATCCGGGTAATTTTGCCACCAATATTCAGGCCGGTGCCTCATA
CGGCTACACCCTGCTGTGGGTGGTGGTGTGGGCCAACCTGATGGCGATGCTGATTCAGCTGCTGTCGGCCAAGCTGGGGA
TTGCGACCGGAAAAAATCTGGCAGAACATATCCGAGATCGCTTCCCGCGCCCGGCGGTATGGGCCTATTGGGTGCAGGCC
GAGATCATCGCGATAGCCACGGATTTGGCGGAGTTTATCGGCGCCGCCATCGGCTTTAAGCTGCTGTTGGGCGTCAGTCT
GCTGCAGGGGGCGGTGCTGACCGGAATCGCGACGTTCCTGATCCTGGGACTACAACGCCGCGGTCAAAAGCCGCTGGAAC
TGGTGATCGGTGCGCTGCTGCTGTTTGTCGCGGCCGCCTATATCGTGGAGCTGGTCTTCTCACGCCCGAGTGTGGCCGGG
CTGGCTCAGGGTATGCTGTTGCCGGAGCTGCCGACGCAGGATGCGGTGGTGCTGGCCGCTGGTGTCCTGGGGGCGACGAT
TATGCCGCATGTTATCTATCTGCATTCGTCGCTGACCCAAAACGGCAGTAAAGGCAGCCGGGCGGAACGCTATGCCTCGA
CCAAACTGGACGTGGCGATAGCCATGACCATTGCCGGCTTTGTTAACTTGGCCATGATGGCGACAGCAGCGGCGGCCTTC
CACTTTAACGGGCACAGTGGGATCAGCGAGCTGGATCAGGCGTACCTGACGCTGAAGCCGCTGCTCGGTGAGGCCGCCGC
CACGATCTTTGGCCTGAGCCTGGTCGCGGCAGGTCTCTCCTCGACGGTGGTGGGGACGCTGGCGGGGCAGGTTGTCATGC
AGGGGTTCGTTCATTTCCACATTCCGCTGTGGCTGCGCCGTGCAGTGACCATGCTGCCGTCGTTTATCGTGATCCTGGCC
GGTCTGGATGCGACCCGTATTCTGGTGCTCAGCCAGGTTTTACTGAGCTTCGGGATCGCCCTGGCGCTGCTGCCGCTGCT
GGCCTTTACCGGTAACCGTGCGCTGATGGGGGACATGGTCAATAGCCGCCTGGTACAGGCAGTGGGCAGGGTGATTGTCT
TTCTGGTGGTCGGGCTTAACCTGTACCTGCTGTTCACCATGTTGGCCGGTTAA

Upstream 100 bases:

>100_bases
GAGATAATAGAAACAACGGCAGTAAGGGCATCTTATGTTGAACTCTCGGACCGTAGACGGCGTCACCCGCTCCCCGGCGC
GCAGGATTAAGATCTCGCTG

Downstream 100 bases:

>100_bases
TCATCGTCATCCTCATTGTGGTGGCGATGCCAGATCGGGCGGCGGCCCTGCTCGTCCCGATCGCCACGCCATTTCCTGTG
GCGCAGCGCGTTCTCTGGCC

Product: manganese transport protein MntH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MGPAFIAAIGYIDPGNFATNIQAGASYGYTLLWVVVWANLMAMLIQLLSAKLGIATGKNLAEHIRDRFPRPAVWAYWVQA
EIIAIATDLAEFIGAAIGFKLLLGVSLLQGAVLTGIATFLILGLQRRGQKPLELVIGALLLFVAAAYIVELVFSRPSVAG
LAQGMLLPELPTQDAVVLAAGVLGATIMPHVIYLHSSLTQNGSKGSRAERYASTKLDVAIAMTIAGFVNLAMMATAAAAF
HFNGHSGISELDQAYLTLKPLLGEAAATIFGLSLVAAGLSSTVVGTLAGQVVMQGFVHFHIPLWLRRAVTMLPSFIVILA
GLDATRILVLSQVLLSFGIALALLPLLAFTGNRALMGDMVNSRLVQAVGRVIVFLVVGLNLYLLFTMLAG

Sequences:

>Translated_390_residues
MGPAFIAAIGYIDPGNFATNIQAGASYGYTLLWVVVWANLMAMLIQLLSAKLGIATGKNLAEHIRDRFPRPAVWAYWVQA
EIIAIATDLAEFIGAAIGFKLLLGVSLLQGAVLTGIATFLILGLQRRGQKPLELVIGALLLFVAAAYIVELVFSRPSVAG
LAQGMLLPELPTQDAVVLAAGVLGATIMPHVIYLHSSLTQNGSKGSRAERYASTKLDVAIAMTIAGFVNLAMMATAAAAF
HFNGHSGISELDQAYLTLKPLLGEAAATIFGLSLVAAGLSSTVVGTLAGQVVMQGFVHFHIPLWLRRAVTMLPSFIVILA
GLDATRILVLSQVLLSFGIALALLPLLAFTGNRALMGDMVNSRLVQAVGRVIVFLVVGLNLYLLFTMLAG
>Mature_389_residues
GPAFIAAIGYIDPGNFATNIQAGASYGYTLLWVVVWANLMAMLIQLLSAKLGIATGKNLAEHIRDRFPRPAVWAYWVQAE
IIAIATDLAEFIGAAIGFKLLLGVSLLQGAVLTGIATFLILGLQRRGQKPLELVIGALLLFVAAAYIVELVFSRPSVAGL
AQGMLLPELPTQDAVVLAAGVLGATIMPHVIYLHSSLTQNGSKGSRAERYASTKLDVAIAMTIAGFVNLAMMATAAAAFH
FNGHSGISELDQAYLTLKPLLGEAAATIFGLSLVAAGLSSTVVGTLAGQVVMQGFVHFHIPLWLRRAVTMLPSFIVILAG
LDATRILVLSQVLLSFGIALALLPLLAFTGNRALMGDMVNSRLVQAVGRVIVFLVVGLNLYLLFTMLAG

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=431, Percent_Identity=33.1786542923434, Blast_Score=201, Evalue=8e-52,
Organism=Homo sapiens, GI295293171, Length=421, Percent_Identity=31.1163895486936, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI295293169, Length=421, Percent_Identity=31.1163895486936, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI295293178, Length=421, Percent_Identity=31.1163895486936, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI295293175, Length=421, Percent_Identity=31.1163895486936, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI295293173, Length=421, Percent_Identity=31.1163895486936, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI10835169, Length=421, Percent_Identity=31.1163895486936, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI295293167, Length=421, Percent_Identity=31.1163895486936, Blast_Score=160, Evalue=2e-39,
Organism=Escherichia coli, GI1788736, Length=384, Percent_Identity=82.03125, Blast_Score=609, Evalue=1e-175,
Organism=Caenorhabditis elegans, GI193210616, Length=425, Percent_Identity=30.3529411764706, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17569473, Length=394, Percent_Identity=30.7106598984772, Blast_Score=184, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI71999499, Length=431, Percent_Identity=28.7703016241299, Blast_Score=161, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI71993856, Length=218, Percent_Identity=37.1559633027523, Blast_Score=136, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6323062, Length=455, Percent_Identity=31.4285714285714, Blast_Score=184, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6324450, Length=411, Percent_Identity=29.4403892944039, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6321841, Length=408, Percent_Identity=30.1470588235294, Blast_Score=149, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24648607, Length=426, Percent_Identity=31.924882629108, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI281362176, Length=426, Percent_Identity=31.924882629108, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24648609, Length=426, Percent_Identity=31.924882629108, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI45553443, Length=403, Percent_Identity=32.258064516129, Blast_Score=204, Evalue=7e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 41148; Mature: 41016

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GPAFIAAIGYIDPGNFATNIQAGASYGYTLLWVVVWANLMAMLIQLLSAKLGIATGKNL
CCHHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AEHIRDRFPRPAVWAYWVQAEIIAIATDLAEFIGAAIGFKLLLGVSLLQGAVLTGIATFL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILGLQRRGQKPLELVIGALLLFVAAAYIVELVFSRPSVAGLAQGMLLPELPTQDAVVLAA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCHHHHHH
GVLGATIMPHVIYLHSSLTQNGSKGSRAERYASTKLDVAIAMTIAGFVNLAMMATAAAAF
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HFNGHSGISELDQAYLTLKPLLGEAAATIFGLSLVAAGLSSTVVGTLAGQVVMQGFVHFH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPLWLRRAVTMLPSFIVILAGLDATRILVLSQVLLSFGIALALLPLLAFTGNRALMGDMV
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
NSRLVQAVGRVIVFLVVGLNLYLLFTMLAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA