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The map label for this gene is glk

Identifier: 238919186

GI number: 238919186

Start: 1250572

End: 1251537

Strand: Direct

Name: glk

Synonym: NT01EI_1269

Alternate gene names: 238919186

Gene position: 1250572-1251537 (Clockwise)

Preceding gene: 238919184

Following gene: 238919188

Centisome position: 32.8

GC content: 64.6

Gene sequence:

>966_bases
ATGAGCCGTTTTGCGTTGGTTGGTGATGTGGGTGGGACCAATGCCCGCCTGGCGCTGTGTTGCCTCGATACGGGCTCTCT
CGAGGCGGTGCAGAGCTACCCGGGACAGCAGTTTGATAGCCTGGAGTCGGTCATCCGGACCTACCTGCAGGCGCAGGCGG
TATCGGTGACGTCGGCCTGCATCGCCATCGCCTGTCCGATCACCGGCGATCGCGTGGCGATGACCAATCACAGCTGGGCG
TTTTCCATCAGCGCGATGCAGCGCTCTCTGGGGCTGGCGCATCTGTCGGTGATCAACGACTTTACCGCGGTCTCTATGGC
GGTGCCGGTTCTCCCTGCGGAGAGTCTGCTGCAGTTGGGCGGTCAGACGGTGCAGCCAGATCGGCCTATCGCCATCTACG
GCGCCGGTACCGGGCTGGGCGTCGCTCACCTGATCCGGGCCGGGGAGCGCTGGATCAGCCTGCCGGGAGAGGGAGGTCAC
GTGGACTTCGCGACCGGCAGTGATGAAGAGGACGCACTGCTGGCGGCGCTGCGCACTGATCTGGGGCGGGTCTCTGCCGA
GCGGGTGCTCTCAGGGCCTGGTCTGGTCAATTTGTATCGTGCCGTCGCCCGGGTTGCGGGACGGACGCCTCAGCCCCTGA
CGCCACAGGAGGTCAGCGAGCGGGCGCTGGCTGACCACTGCCCGGACTGTCGGCGGGCGCTGTCACTGTTCTGTGTGATG
ATGGGGCGCTTTGGCGGCAATCTGGCGCTGAATATGGGCACCTTTGGTGGGGTGTATATCGCCGGTGGGATCGTGCCGCG
TTTTCTGGCTTTTTTCCGCGACTCCGGCTTTCGTCAGGCGTTTGAGGACAAGGGGCGCTTTAAGGCGTACCTTGCGCCGA
TCCCGGTCTTTCTGATCGTGCATGATAACCCCGGCCTGCTTGGTGCCGGAGCCTACCTGCGTCAGCACTTAGGCGCCCGC
CTCTAG

Upstream 100 bases:

>100_bases
CATACTGTTCGATGACATGCATAGGCTCTCCGTCGGTATGGCGGGGCTGTAGAGGTGATCCCGCTAAGACGCGGCAGAGA
GAAAGGGGGAGTGACGGAAA

Downstream 100 bases:

>100_bases
GGTGCCATCGCCGCATCCCGCTGCGGGGTGCGGCACCAGGGACGGGCGCGGCTGGTGAGCGCCACAGCTCAGCTCGGCTC
ATCCCACTCTGCGGTGGCGT

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSRFALVGDVGGTNARLALCCLDTGSLEAVQSYPGQQFDSLESVIRTYLQAQAVSVTSACIAIACPITGDRVAMTNHSWA
FSISAMQRSLGLAHLSVINDFTAVSMAVPVLPAESLLQLGGQTVQPDRPIAIYGAGTGLGVAHLIRAGERWISLPGEGGH
VDFATGSDEEDALLAALRTDLGRVSAERVLSGPGLVNLYRAVARVAGRTPQPLTPQEVSERALADHCPDCRRALSLFCVM
MGRFGGNLALNMGTFGGVYIAGGIVPRFLAFFRDSGFRQAFEDKGRFKAYLAPIPVFLIVHDNPGLLGAGAYLRQHLGAR
L

Sequences:

>Translated_321_residues
MSRFALVGDVGGTNARLALCCLDTGSLEAVQSYPGQQFDSLESVIRTYLQAQAVSVTSACIAIACPITGDRVAMTNHSWA
FSISAMQRSLGLAHLSVINDFTAVSMAVPVLPAESLLQLGGQTVQPDRPIAIYGAGTGLGVAHLIRAGERWISLPGEGGH
VDFATGSDEEDALLAALRTDLGRVSAERVLSGPGLVNLYRAVARVAGRTPQPLTPQEVSERALADHCPDCRRALSLFCVM
MGRFGGNLALNMGTFGGVYIAGGIVPRFLAFFRDSGFRQAFEDKGRFKAYLAPIPVFLIVHDNPGLLGAGAYLRQHLGAR
L
>Mature_320_residues
SRFALVGDVGGTNARLALCCLDTGSLEAVQSYPGQQFDSLESVIRTYLQAQAVSVTSACIAIACPITGDRVAMTNHSWAF
SISAMQRSLGLAHLSVINDFTAVSMAVPVLPAESLLQLGGQTVQPDRPIAIYGAGTGLGVAHLIRAGERWISLPGEGGHV
DFATGSDEEDALLAALRTDLGRVSAERVLSGPGLVNLYRAVARVAGRTPQPLTPQEVSERALADHCPDCRRALSLFCVMM
GRFGGNLALNMGTFGGVYIAGGIVPRFLAFFRDSGFRQAFEDKGRFKAYLAPIPVFLIVHDNPGLLGAGAYLRQHLGARL

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family

Homologues:

Organism=Escherichia coli, GI1788732, Length=318, Percent_Identity=67.2955974842767, Blast_Score=462, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLK_EDWI9 (C5BCK8)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002932701.1
- GeneID:   7960598
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_1269
- OMA:   LGMTRLK
- ProtClustDB:   PRK00292
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00524
- InterPro:   IPR003836
- TIGRFAMs:   TIGR00749

Pfam domain/function: PF02685 Glucokinase

EC number: =2.7.1.2

Molecular weight: Translated: 34015; Mature: 33883

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFALVGDVGGTNARLALCCLDTGSLEAVQSYPGQQFDSLESVIRTYLQAQAVSVTSAC
CCCEEEEECCCCCCCEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IAIACPITGDRVAMTNHSWAFSISAMQRSLGLAHLSVINDFTAVSMAVPVLPAESLLQLG
EEEECCCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHC
GQTVQPDRPIAIYGAGTGLGVAHLIRAGERWISLPGEGGHVDFATGSDEEDALLAALRTD
CCCCCCCCCEEEEECCCCHHHHHHHHCCHHEEECCCCCCEEEECCCCCCHHHHHHHHHHH
LGRVSAERVLSGPGLVNLYRAVARVAGRTPQPLTPQEVSERALADHCPDCRRALSLFCVM
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
MGRFGGNLALNMGTFGGVYIAGGIVPRFLAFFRDSGFRQAFEDKGRFKAYLAPIPVFLIV
HHCCCCCEEEECCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHCCCCEEEEECCCEEEEEE
HDNPGLLGAGAYLRQHLGARL
ECCCCCEEHHHHHHHHHCCCC
>Mature Secondary Structure 
SRFALVGDVGGTNARLALCCLDTGSLEAVQSYPGQQFDSLESVIRTYLQAQAVSVTSAC
CCEEEEECCCCCCCEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IAIACPITGDRVAMTNHSWAFSISAMQRSLGLAHLSVINDFTAVSMAVPVLPAESLLQLG
EEEECCCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHC
GQTVQPDRPIAIYGAGTGLGVAHLIRAGERWISLPGEGGHVDFATGSDEEDALLAALRTD
CCCCCCCCCEEEEECCCCHHHHHHHHCCHHEEECCCCCCEEEECCCCCCHHHHHHHHHHH
LGRVSAERVLSGPGLVNLYRAVARVAGRTPQPLTPQEVSERALADHCPDCRRALSLFCVM
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
MGRFGGNLALNMGTFGGVYIAGGIVPRFLAFFRDSGFRQAFEDKGRFKAYLAPIPVFLIV
HHCCCCCEEEECCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHCCCCEEEEECCCEEEEEE
HDNPGLLGAGAYLRQHLGARL
ECCCCCEEHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA