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The map label for this gene is hrcA [H]

Identifier: 238917287

GI number: 238917287

Start: 1401288

End: 1402415

Strand: Reverse

Name: hrcA [H]

Synonym: EUBELI_01362

Alternate gene names: 238917287

Gene position: 1402415-1401288 (Counterclockwise)

Preceding gene: 238917289

Following gene: 238917286

Centisome position: 65.41

GC content: 40.34

Gene sequence:

>1128_bases
ATGAGTGCTAACAAGATGAAAGGAGAGGATGCCATGGAGACGGATGGACGACTGGATGACCGTAAGGTTAAGATACTTAA
AGCTGTTATTCAGAATTATCTTGATACCGGAGAACCGGTTGGCTCAAGAACGATTTCCAAGCTGACTGACTTACAGCTAA
GTTCAGCAACTATAAGGAATGAGATGGCAGACTTAGAAGAGCTTGGCTACATTGTACAGCCACATACCTCTGCTGGAAGA
ATTCCAACTGATAAGGGTTACAGATTATATGTTGACGATTTAATGGCCCAGAAAGAGGAAGAGATATCCTTAAGAGAACA
GCAGGTTGGTGATAAAGAGAAAGAACTTGATTCTATGAAGGATGCCTTATCAGAGAAGGTAGACAGAGTAGAGGAGCTTC
TTCAGAATGTAGCAAAGGTTCTGGCGAATAATACTAATTATGCCACGATGATAACAACTCCTAAGGTAACTGGTAATAAG
TTAAGATTTGTTCAGCTTTCACAGCTTGAACCGAATAAGCTTCTTGCTGTTATTGTTATGGAAGGTAATCTTATAAGGAA
CAAGGTTATAACTATCAGCGAGGATATTTCACCAGAGAATCTTCTGAAGCTTAATCTTCTTCTTAATACAACACTCACAG
GTCTTACATTGCAGGAAATGCATCTGGGACTTATATCCAAGATGGAGAGCCAGGCAGGTGAGCATATGGGTATTGTTAAA
GAAGTGTTAGACGCGATTGTTGAGACTATAAGTAAGGCTGACGACCTGAAGATATACACAAGCGGCGCAACTAACATATT
CAAGTATCCGGAGCTTAGTGATTCCGGGAAAGCAAGTGAGCTTATATATGCCTTGGAGGAAAAACAGGGCTTGTCTGGAC
TTGTTAATGACAAGGATGATTCAGATAAGACTGAAGATGATAACCACGGCATTCAGGTATATATAGGAAATGAAACACCG
GTTGAGTCCATGAAGGACTGTAGTGTGGTAACAGCCACATATGAATTGCAGGATGGAATGAAGGGAACAATTGGTATTAT
TGGACCGAAGCGTATGGATTATGAAAAGGTTGTTGATACCTTAAAAGAGATGCAGACGCATTTGGATGATGTATTTAAGA
AAACTTAG

Upstream 100 bases:

>100_bases
AATAAATTTATAAATTATTTATAGAAAAAAGAAATATTATTGTTGACATCACGAAAGGGTAGTGATATCTTAAATGTATC
GATATTAGCACTCCAATCTG

Downstream 100 bases:

>100_bases
GAAAGGTTGGTATTGAAGTGTCAAAGGATGTAAAGAAAAAGAAATCAGAAGAGACAGTTCAGGATGAAGTAAAGAATCAG
GAGACTGATGCTAAGAAAGA

Product: heat-inducible transcriptional repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MSANKMKGEDAMETDGRLDDRKVKILKAVIQNYLDTGEPVGSRTISKLTDLQLSSATIRNEMADLEELGYIVQPHTSAGR
IPTDKGYRLYVDDLMAQKEEEISLREQQVGDKEKELDSMKDALSEKVDRVEELLQNVAKVLANNTNYATMITTPKVTGNK
LRFVQLSQLEPNKLLAVIVMEGNLIRNKVITISEDISPENLLKLNLLLNTTLTGLTLQEMHLGLISKMESQAGEHMGIVK
EVLDAIVETISKADDLKIYTSGATNIFKYPELSDSGKASELIYALEEKQGLSGLVNDKDDSDKTEDDNHGIQVYIGNETP
VESMKDCSVVTATYELQDGMKGTIGIIGPKRMDYEKVVDTLKEMQTHLDDVFKKT

Sequences:

>Translated_375_residues
MSANKMKGEDAMETDGRLDDRKVKILKAVIQNYLDTGEPVGSRTISKLTDLQLSSATIRNEMADLEELGYIVQPHTSAGR
IPTDKGYRLYVDDLMAQKEEEISLREQQVGDKEKELDSMKDALSEKVDRVEELLQNVAKVLANNTNYATMITTPKVTGNK
LRFVQLSQLEPNKLLAVIVMEGNLIRNKVITISEDISPENLLKLNLLLNTTLTGLTLQEMHLGLISKMESQAGEHMGIVK
EVLDAIVETISKADDLKIYTSGATNIFKYPELSDSGKASELIYALEEKQGLSGLVNDKDDSDKTEDDNHGIQVYIGNETP
VESMKDCSVVTATYELQDGMKGTIGIIGPKRMDYEKVVDTLKEMQTHLDDVFKKT
>Mature_374_residues
SANKMKGEDAMETDGRLDDRKVKILKAVIQNYLDTGEPVGSRTISKLTDLQLSSATIRNEMADLEELGYIVQPHTSAGRI
PTDKGYRLYVDDLMAQKEEEISLREQQVGDKEKELDSMKDALSEKVDRVEELLQNVAKVLANNTNYATMITTPKVTGNKL
RFVQLSQLEPNKLLAVIVMEGNLIRNKVITISEDISPENLLKLNLLLNTTLTGLTLQEMHLGLISKMESQAGEHMGIVKE
VLDAIVETISKADDLKIYTSGATNIFKYPELSDSGKASELIYALEEKQGLSGLVNDKDDSDKTEDDNHGIQVYIGNETPV
ESMKDCSVVTATYELQDGMKGTIGIIGPKRMDYEKVVDTLKEMQTHLDDVFKKT

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 41721; Mature: 41590

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANKMKGEDAMETDGRLDDRKVKILKAVIQNYLDTGEPVGSRTISKLTDLQLSSATIRN
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
EMADLEELGYIVQPHTSAGRIPTDKGYRLYVDDLMAQKEEEISLREQQVGDKEKELDSMK
HHHHHHHCCCEECCCCCCCCCCCCCCCEEEHHHHHHCCHHHHHHHHHHCCCHHHHHHHHH
DALSEKVDRVEELLQNVAKVLANNTNYATMITTPKVTGNKLRFVQLSQLEPNKLLAVIVM
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCCCCEEEEEEE
EGNLIRNKVITISEDISPENLLKLNLLLNTTLTGLTLQEMHLGLISKMESQAGEHMGIVK
CCCEEECEEEEEECCCCCCHHEEEEEEECCHHCCCCHHHHHHHHHHHHHHHCCHHHHHHH
EVLDAIVETISKADDLKIYTSGATNIFKYPELSDSGKASELIYALEEKQGLSGLVNDKDD
HHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
SDKTEDDNHGIQVYIGNETPVESMKDCSVVTATYELQDGMKGTIGIIGPKRMDYEKVVDT
CCCCCCCCCCEEEEECCCCCHHHHHCCEEEEEEEECCCCCCCEEEECCCCCCCHHHHHHH
LKEMQTHLDDVFKKT
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
SANKMKGEDAMETDGRLDDRKVKILKAVIQNYLDTGEPVGSRTISKLTDLQLSSATIRN
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
EMADLEELGYIVQPHTSAGRIPTDKGYRLYVDDLMAQKEEEISLREQQVGDKEKELDSMK
HHHHHHHCCCEECCCCCCCCCCCCCCCEEEHHHHHHCCHHHHHHHHHHCCCHHHHHHHHH
DALSEKVDRVEELLQNVAKVLANNTNYATMITTPKVTGNKLRFVQLSQLEPNKLLAVIVM
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCCCCEEEEEEE
EGNLIRNKVITISEDISPENLLKLNLLLNTTLTGLTLQEMHLGLISKMESQAGEHMGIVK
CCCEEECEEEEEECCCCCCHHEEEEEEECCHHCCCCHHHHHHHHHHHHHHHCCHHHHHHH
EVLDAIVETISKADDLKIYTSGATNIFKYPELSDSGKASELIYALEEKQGLSGLVNDKDD
HHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
SDKTEDDNHGIQVYIGNETPVESMKDCSVVTATYELQDGMKGTIGIIGPKRMDYEKVVDT
CCCCCCCCCCEEEEECCCCCHHHHHCCEEEEEEEECCCCCCCEEEECCCCCCCHHHHHHH
LKEMQTHLDDVFKKT
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA