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The map label for this gene is trpGD [H]

Identifier: 238917232

GI number: 238917232

Start: 1342074

End: 1342643

Strand: Reverse

Name: trpGD [H]

Synonym: EUBELI_01305

Alternate gene names: 238917232

Gene position: 1342643-1342074 (Counterclockwise)

Preceding gene: 238917233

Following gene: 238917231

Centisome position: 62.62

GC content: 37.89

Gene sequence:

>570_bases
ATGATTCTGCTGATTGATAATTATGACTCATTTACATATAACCTGTATCAGTTTATTGGAATATTTAACAGTGATATTAA
GGTTGTAAGAAACGATAAGATAACAATTGAGGAGATAGAGGAGCTTGACCCTGAATCAATAGTTGTATCTCCTGGCCCTA
AGAGCCCTAAAGATGCTGGAATATGTGTTGATGTAATAAAGCATTTTACAGGAAAGAAGCCGATACTTGGTATATGTTTG
GGACATCAGTGCATAGGAGAAGCATTTGGCGCGACTGTTTCTTATGCAAAATGTATCATGCATGGTAAACAGTCTGAAAT
ATACCATGATGGAACAGGAATATTTACCGGACTTGATTCACCAGTAAAGGTTGCAAGATATCATTCACTCGCTATAATTG
AAGAGACTTTGCCAGACTGCCTGGAGATTATTGCCAAGACACAGGATGGAGAAATAATGGCTGTAAAACATGAGGATTAT
CCGGTGGTCGGATTGCAGTTCCATCCGGAGTCAATATATACAGAGCATGGCAAGAGAATGATTGAGAATTTTGTTAATGG
GGTGATTTAA

Upstream 100 bases:

>100_bases
GTGCAGGAATTGTTGCTGATTCAAAGCCTGAGATGGAATATCAGGAGTGCTGCAATAAAGTAATGGCACTTGCAAAGACA
CTTGTTAAGGAGGAACATTT

Downstream 100 bases:

>100_bases
TGATATTAGATGTTATTGTAGAGGATAAGTTAAAAAGACTTCCAGAACACAAGAAAAGAATCAGTGAAGAGGAGATGACA
AGACTTGCGATTGAGAGCCA

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amidotransferase; Anthranilate phosphoribosyltransferase [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MILLIDNYDSFTYNLYQFIGIFNSDIKVVRNDKITIEEIEELDPESIVVSPGPKSPKDAGICVDVIKHFTGKKPILGICL
GHQCIGEAFGATVSYAKCIMHGKQSEIYHDGTGIFTGLDSPVKVARYHSLAIIEETLPDCLEIIAKTQDGEIMAVKHEDY
PVVGLQFHPESIYTEHGKRMIENFVNGVI

Sequences:

>Translated_189_residues
MILLIDNYDSFTYNLYQFIGIFNSDIKVVRNDKITIEEIEELDPESIVVSPGPKSPKDAGICVDVIKHFTGKKPILGICL
GHQCIGEAFGATVSYAKCIMHGKQSEIYHDGTGIFTGLDSPVKVARYHSLAIIEETLPDCLEIIAKTQDGEIMAVKHEDY
PVVGLQFHPESIYTEHGKRMIENFVNGVI
>Mature_189_residues
MILLIDNYDSFTYNLYQFIGIFNSDIKVVRNDKITIEEIEELDPESIVVSPGPKSPKDAGICVDVIKHFTGKKPILGICL
GHQCIGEAFGATVSYAKCIMHGKQSEIYHDGTGIFTGLDSPVKVARYHSLAIIEETLPDCLEIIAKTQDGEIMAVKHEDY
PVVGLQFHPESIYTEHGKRMIENFVNGVI

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=186, Percent_Identity=50, Blast_Score=216, Evalue=5e-58,
Organism=Escherichia coli, GI1787517, Length=185, Percent_Identity=44.3243243243243, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1786215, Length=141, Percent_Identity=28.3687943262411, Blast_Score=64, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=186, Percent_Identity=51.0752688172043, Blast_Score=205, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=32.7014218009479, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase; PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =4.1.3.27; =2.4.2.18 [H]

Molecular weight: Translated: 21014; Mature: 21014

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLIDNYDSFTYNLYQFIGIFNSDIKVVRNDKITIEEIEELDPESIVVSPGPKSPKDAG
CEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCEEHHHHHHCCCCEEEECCCCCCCCCCC
ICVDVIKHFTGKKPILGICLGHQCIGEAFGATVSYAKCIMHGKQSEIYHDGTGIFTGLDS
HHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEECCCC
PVKVARYHSLAIIEETLPDCLEIIAKTQDGEIMAVKHEDYPVVGLQFHPESIYTEHGKRM
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHH
IENFVNGVI
HHHHHCCCC
>Mature Secondary Structure
MILLIDNYDSFTYNLYQFIGIFNSDIKVVRNDKITIEEIEELDPESIVVSPGPKSPKDAG
CEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCEEHHHHHHCCCCEEEECCCCCCCCCCC
ICVDVIKHFTGKKPILGICLGHQCIGEAFGATVSYAKCIMHGKQSEIYHDGTGIFTGLDS
HHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEECCCC
PVKVARYHSLAIIEETLPDCLEIIAKTQDGEIMAVKHEDYPVVGLQFHPESIYTEHGKRM
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHH
IENFVNGVI
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685830; 10360571; 7556082 [H]