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The map label for this gene is trpE [H]

Identifier: 238917233

GI number: 238917233

Start: 1342640

End: 1344058

Strand: Reverse

Name: trpE [H]

Synonym: EUBELI_01306

Alternate gene names: 238917233

Gene position: 1344058-1342640 (Counterclockwise)

Preceding gene: 238917234

Following gene: 238917232

Centisome position: 62.68

GC content: 38.48

Gene sequence:

>1419_bases
ATGAAACGAAGATTAAGAGCTTATAAGAAGACGGTAAGTATCGTTAATGAGAAAGCTATTGAACTATACAAAGGACTTGG
AATTGAAAAGAAGGGATTTCTTCTTGAAGGAACTGACAAGGAAAGCGGACAGTATACTTTTATGGGAGTTGAACCGAATG
AGATAATCCAATCAGATAAGGACAGCCTTGTTATTACAAGAAAAGATGGAAGCAGAGAGGTAAGAGAGGGCAATCCTCTT
ATAAGACTTAAAGAGTATTTTGATGAATTCGAGATAGTAAAGGATCCGGGAGAACTTGATTTCATCGGAGGTCTTGTTGG
AAGCCTTGGATATGATTATATAAGATACACAGAAGTCCTTCCTGATGATAATCCTGATGAGATAGGAATTGAGACAATAC
AGCTTATGCTTGCAGACAAGTTCATTGCTATCAATCATACAGCAGAAACATTCACAGCAGTAGTGCTTGGAGAGGATTCA
GAGGAAGGCAGGATTAAGGCTTTAAAGGAAGCGGAGGAGCTTATAAAGACTGCAAGAGAGGGTGTAGATAAGTTTAAGGA
TGATAAGCCTGATATGTCACTTGATGGTGTAATATTGAAAAAATCGGACACGCTTGAACAATATAGCAAGAAGGTTAATA
AGATTAAGAATTACATAAAAGAAGGTCATATATTCCAGACTGTTCTTTCGCAGAGATGGACAATAAAGACGGGACAGAGC
GGTTTTAATCTCTATGAAAAATTAAGAGAACTTAATCCTTCACCATATATGTATTATTTTAATTTCGGCGATTTTGAGAT
AATCGGAAGTTCACCGGAAATGATTGTAAAGCAGTCAGACAATAAAGTATATACATGTCCTATAGCGGGCACAAGAAAAA
GAGGAGCAACAAAGGAACAGGATATTGCTTTAGAGGAAGAACTTCTTGCAGATGAGAAAGAGAGAGCAGAGCATGTAATG
TTAGTTGACCTTGCACGTAACGATATGGGTAGGATAAGTGAGATAGGAACAGTCAAGGTTGACCAGTTCATGAATATCCA
GAGATATTCACATGTTATGCATATTGTTTCACTTGTTGAGGGAAGAAAGAATGGAGAATATCATCCACTTGACCTCGTAT
CATCATTCCTTCCAGCAGGCACATTAAGCGGCGCACCTAAGATAAGAGCAATGGAAATCATAGATGAGCTTGAGACAGTA
AGAAGAGGCCTGTATGGAGGAGCTACAGGATACCTTGATTTTGGCGGTAATATGAACTTCTGCATTACAATCAGGACTAT
GATTAAGAAAGGCGATAAGGTATATCTTCAGGCAGGTGCAGGAATTGTTGCTGATTCAAAGCCTGAGATGGAATATCAGG
AGTGCTGCAATAAAGTAATGGCACTTGCAAAGACACTTGTTAAGGAGGAACATTTATGA

Upstream 100 bases:

>100_bases
TTCGTCCCTGACAGGAATCTGCAATATACAGGTTCCTGTCAGGGACATTTTTTGTAAGCAGCAGACGCCAGTAATGAACA
ACGAAGGATAGGGAGGAACT

Downstream 100 bases:

>100_bases
TTCTGCTGATTGATAATTATGACTCATTTACATATAACCTGTATCAGTTTATTGGAATATTTAACAGTGATATTAAGGTT
GTAAGAAACGATAAGATAAC

Product: anthranilate synthase component I

Products: NA

Alternate protein names: Anthranilate synthase component I [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MKRRLRAYKKTVSIVNEKAIELYKGLGIEKKGFLLEGTDKESGQYTFMGVEPNEIIQSDKDSLVITRKDGSREVREGNPL
IRLKEYFDEFEIVKDPGELDFIGGLVGSLGYDYIRYTEVLPDDNPDEIGIETIQLMLADKFIAINHTAETFTAVVLGEDS
EEGRIKALKEAEELIKTAREGVDKFKDDKPDMSLDGVILKKSDTLEQYSKKVNKIKNYIKEGHIFQTVLSQRWTIKTGQS
GFNLYEKLRELNPSPYMYYFNFGDFEIIGSSPEMIVKQSDNKVYTCPIAGTRKRGATKEQDIALEEELLADEKERAEHVM
LVDLARNDMGRISEIGTVKVDQFMNIQRYSHVMHIVSLVEGRKNGEYHPLDLVSSFLPAGTLSGAPKIRAMEIIDELETV
RRGLYGGATGYLDFGGNMNFCITIRTMIKKGDKVYLQAGAGIVADSKPEMEYQECCNKVMALAKTLVKEEHL

Sequences:

>Translated_472_residues
MKRRLRAYKKTVSIVNEKAIELYKGLGIEKKGFLLEGTDKESGQYTFMGVEPNEIIQSDKDSLVITRKDGSREVREGNPL
IRLKEYFDEFEIVKDPGELDFIGGLVGSLGYDYIRYTEVLPDDNPDEIGIETIQLMLADKFIAINHTAETFTAVVLGEDS
EEGRIKALKEAEELIKTAREGVDKFKDDKPDMSLDGVILKKSDTLEQYSKKVNKIKNYIKEGHIFQTVLSQRWTIKTGQS
GFNLYEKLRELNPSPYMYYFNFGDFEIIGSSPEMIVKQSDNKVYTCPIAGTRKRGATKEQDIALEEELLADEKERAEHVM
LVDLARNDMGRISEIGTVKVDQFMNIQRYSHVMHIVSLVEGRKNGEYHPLDLVSSFLPAGTLSGAPKIRAMEIIDELETV
RRGLYGGATGYLDFGGNMNFCITIRTMIKKGDKVYLQAGAGIVADSKPEMEYQECCNKVMALAKTLVKEEHL
>Mature_472_residues
MKRRLRAYKKTVSIVNEKAIELYKGLGIEKKGFLLEGTDKESGQYTFMGVEPNEIIQSDKDSLVITRKDGSREVREGNPL
IRLKEYFDEFEIVKDPGELDFIGGLVGSLGYDYIRYTEVLPDDNPDEIGIETIQLMLADKFIAINHTAETFTAVVLGEDS
EEGRIKALKEAEELIKTAREGVDKFKDDKPDMSLDGVILKKSDTLEQYSKKVNKIKNYIKEGHIFQTVLSQRWTIKTGQS
GFNLYEKLRELNPSPYMYYFNFGDFEIIGSSPEMIVKQSDNKVYTCPIAGTRKRGATKEQDIALEEELLADEKERAEHVM
LVDLARNDMGRISEIGTVKVDQFMNIQRYSHVMHIVSLVEGRKNGEYHPLDLVSSFLPAGTLSGAPKIRAMEIIDELETV
RRGLYGGATGYLDFGGNMNFCITIRTMIKKGDKVYLQAGAGIVADSKPEMEYQECCNKVMALAKTLVKEEHL

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=398, Percent_Identity=32.4120603015075, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1787518, Length=401, Percent_Identity=34.1645885286783, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1786809, Length=213, Percent_Identity=31.4553990610329, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI87082077, Length=223, Percent_Identity=29.1479820627803, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320935, Length=458, Percent_Identity=41.0480349344978, Blast_Score=298, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6324361, Length=405, Percent_Identity=25.9259259259259, Blast_Score=133, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR005256
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 53377; Mature: 53377

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRLRAYKKTVSIVNEKAIELYKGLGIEKKGFLLEGTDKESGQYTFMGVEPNEIIQSDK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCEEEEECCHHHHHHCCC
DSLVITRKDGSREVREGNPLIRLKEYFDEFEIVKDPGELDFIGGLVGSLGYDYIRYTEVL
CCEEEEECCCCCHHHCCCCEEEHHHHHCHHHEECCCCCCHHHHHHHHHHCHHHHHHHHCC
PDDNPDEIGIETIQLMLADKFIAINHTAETFTAVVLGEDSEEGRIKALKEAEELIKTARE
CCCCCCHHHHHHHHHHHHCCEEEEECCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
GVDKFKDDKPDMSLDGVILKKSDTLEQYSKKVNKIKNYIKEGHIFQTVLSQRWTIKTGQS
HHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCEEECCCC
GFNLYEKLRELNPSPYMYYFNFGDFEIIGSSPEMIVKQSDNKVYTCPIAGTRKRGATKEQ
HHHHHHHHHHCCCCCEEEEEECCCEEEECCCCCEEEEECCCEEEEECCCCCCCCCCCCHH
DIALEEELLADEKERAEHVMLVDLARNDMGRISEIGTVKVDQFMNIQRYSHVMHIVSLVE
HHHHHHHHHCCHHHHCCEEEEEEEHHCCCCHHHHCCCEEHHHHHHHHHHHHHHHHHHHHH
GRKNGEYHPLDLVSSFLPAGTLSGAPKIRAMEIIDELETVRRGLYGGATGYLDFGGNMNF
CCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEE
CITIRTMIKKGDKVYLQAGAGIVADSKPEMEYQECCNKVMALAKTLVKEEHL
EEEEEHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRRLRAYKKTVSIVNEKAIELYKGLGIEKKGFLLEGTDKESGQYTFMGVEPNEIIQSDK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCEEEEECCHHHHHHCCC
DSLVITRKDGSREVREGNPLIRLKEYFDEFEIVKDPGELDFIGGLVGSLGYDYIRYTEVL
CCEEEEECCCCCHHHCCCCEEEHHHHHCHHHEECCCCCCHHHHHHHHHHCHHHHHHHHCC
PDDNPDEIGIETIQLMLADKFIAINHTAETFTAVVLGEDSEEGRIKALKEAEELIKTARE
CCCCCCHHHHHHHHHHHHCCEEEEECCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
GVDKFKDDKPDMSLDGVILKKSDTLEQYSKKVNKIKNYIKEGHIFQTVLSQRWTIKTGQS
HHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCEEECCCC
GFNLYEKLRELNPSPYMYYFNFGDFEIIGSSPEMIVKQSDNKVYTCPIAGTRKRGATKEQ
HHHHHHHHHHCCCCCEEEEEECCCEEEECCCCCEEEEECCCEEEEECCCCCCCCCCCCHH
DIALEEELLADEKERAEHVMLVDLARNDMGRISEIGTVKVDQFMNIQRYSHVMHIVSLVE
HHHHHHHHHCCHHHHCCEEEEEEEHHCCCCHHHHCCCEEHHHHHHHHHHHHHHHHHHHHH
GRKNGEYHPLDLVSSFLPAGTLSGAPKIRAMEIIDELETVRRGLYGGATGYLDFGGNMNF
CCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEE
CITIRTMIKKGDKVYLQAGAGIVADSKPEMEYQECCNKVMALAKTLVKEEHL
EEEEEHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2732211 [H]