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The map label for this gene is resD [H]

Identifier: 238916038

GI number: 238916038

Start: 76665

End: 77381

Strand: Direct

Name: resD [H]

Synonym: EUBELI_00071

Alternate gene names: 238916038

Gene position: 76665-77381 (Clockwise)

Preceding gene: 238916037

Following gene: 238916040

Centisome position: 3.58

GC content: 38.91

Gene sequence:

>717_bases
ATGAAACTACACGAAAGGGGACTGGCTATGAGCAAGATATTAATTGTAGAAGATGAAGAGAGTATTGCAGATATTGAGAA
GGATTACCTTGAACTTAACGGATATGAGGTTGAGGTATGTAATGATGGAACAAGTGGCCTTGCGGCTGCACTGCATGAGG
ATATTGATATGTGTATCCTTGATATTATGCTTCCCGGAACTGATGGTTTCGAGATATGCAAGCAGGTAAGAGAAGTTAAG
GATATTCCTATTATCATGGTATCTGCCAAGAAGGAAGATATTGATAAGATAAGAGGGCTTGGAGTTGGTGCGGATGATTA
CATGACCAAGCCATTCAGCCCTAGTGAGCTTGTTGCAAGAGTAAAGGCACATCTTGCAAGATATGACAGACTTGTAAGTA
ATTCTAAGAACAATAACAATATTATTGAAATCAGAGGAATAAAGATTGATAAGACAGCAAGAAGAGTATTTGTTAATGGT
GAGGAGAAGCCATTTACAACAAAGGAATTCGACCTTCTTACGTTCCTTGCAGAGAATCCTAACCATGTCTTCACTAAGGA
AGAACTTTTCAAGGAAATCTGGGATATGGATTCAATCGGTGACATCGCAACTGTAACTGTCCACATCAAGAAAATCAGAG
AGAAGATTGAGCTTGATACAAGCAAGCCTCAGTATATTGAGACAATCTGGGGAGTAGGGTACAGATTTAAAATGTAA

Upstream 100 bases:

>100_bases
ACAAAGGAAAAATATGGGCAGAGAGTGTAGAGGGCGAAGGCACGACCATGCATCTTAATCTGCTTAAAGCAAAGGATGAA
GAGAATCCTGAGAATGCATA

Downstream 100 bases:

>100_bases
AAGACTAAACTTATAGGCTATACCATAATGCAGAATGAGTTTGAAAACATACAAATTGACCTACTAGTTATGAATAGAAA
GCTTGTTCAATAGGTAATTG

Product: two-component system OmpR family phosphate regulon response regulator OmpR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MKLHERGLAMSKILIVEDEESIADIEKDYLELNGYEVEVCNDGTSGLAAALHEDIDMCILDIMLPGTDGFEICKQVREVK
DIPIIMVSAKKEDIDKIRGLGVGADDYMTKPFSPSELVARVKAHLARYDRLVSNSKNNNNIIEIRGIKIDKTARRVFVNG
EEKPFTTKEFDLLTFLAENPNHVFTKEELFKEIWDMDSIGDIATVTVHIKKIREKIELDTSKPQYIETIWGVGYRFKM

Sequences:

>Translated_238_residues
MKLHERGLAMSKILIVEDEESIADIEKDYLELNGYEVEVCNDGTSGLAAALHEDIDMCILDIMLPGTDGFEICKQVREVK
DIPIIMVSAKKEDIDKIRGLGVGADDYMTKPFSPSELVARVKAHLARYDRLVSNSKNNNNIIEIRGIKIDKTARRVFVNG
EEKPFTTKEFDLLTFLAENPNHVFTKEELFKEIWDMDSIGDIATVTVHIKKIREKIELDTSKPQYIETIWGVGYRFKM
>Mature_238_residues
MKLHERGLAMSKILIVEDEESIADIEKDYLELNGYEVEVCNDGTSGLAAALHEDIDMCILDIMLPGTDGFEICKQVREVK
DIPIIMVSAKKEDIDKIRGLGVGADDYMTKPFSPSELVARVKAHLARYDRLVSNSKNNNNIIEIRGIKIDKTARRVFVNG
EEKPFTTKEFDLLTFLAENPNHVFTKEELFKEIWDMDSIGDIATVTVHIKKIREKIELDTSKPQYIETIWGVGYRFKM

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=37.117903930131, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=35.9649122807018, Blast_Score=153, Evalue=8e-39,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=37.3333333333333, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=33.920704845815, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=33.1877729257642, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=33.9285714285714, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=33.1896551724138, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=32.7433628318584, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=30.8370044052863, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=30.8035714285714, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=30.8035714285714, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=30.3571428571429, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787375, Length=230, Percent_Identity=28.695652173913, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=29.1845493562232, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788550, Length=112, Percent_Identity=33.0357142857143, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27127; Mature: 27127

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHERGLAMSKILIVEDEESIADIEKDYLELNGYEVEVCNDGTSGLAAALHEDIDMCIL
CCCCHHCCCEEEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHEEE
DIMLPGTDGFEICKQVREVKDIPIIMVSAKKEDIDKIRGLGVGADDYMTKPFSPSELVAR
EEECCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCCHHHCCCCCCHHHHHHH
VKAHLARYDRLVSNSKNNNNIIEIRGIKIDKTARRVFVNGEEKPFTTKEFDLLTFLAENP
HHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCEEEEECCCCCCCCCCHHHEEEEEECCC
NHVFTKEELFKEIWDMDSIGDIATVTVHIKKIREKIELDTSKPQYIETIWGVGYRFKM
CCEECHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEECC
>Mature Secondary Structure
MKLHERGLAMSKILIVEDEESIADIEKDYLELNGYEVEVCNDGTSGLAAALHEDIDMCIL
CCCCHHCCCEEEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHEEE
DIMLPGTDGFEICKQVREVKDIPIIMVSAKKEDIDKIRGLGVGADDYMTKPFSPSELVAR
EEECCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCCHHHCCCCCCHHHHHHH
VKAHLARYDRLVSNSKNNNNIIEIRGIKIDKTARRVFVNGEEKPFTTKEFDLLTFLAENP
HHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCEEEEECCCCCCCCCCHHHEEEEEECCC
NHVFTKEELFKEIWDMDSIGDIATVTVHIKKIREKIELDTSKPQYIETIWGVGYRFKM
CCEECHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]