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The map label for this gene is yycG [H]

Identifier: 238916037

GI number: 238916037

Start: 75157

End: 76665

Strand: Direct

Name: yycG [H]

Synonym: EUBELI_00070

Alternate gene names: 238916037

Gene position: 75157-76665 (Clockwise)

Preceding gene: 238916036

Following gene: 238916038

Centisome position: 3.51

GC content: 37.77

Gene sequence:

>1509_bases
ATGAAGCTAAAGAATAAGTTGTATATTTCTTTCTGTATTATGGTTATACTTCCTGTGCTTCTGAGTGGTCTTGCTCTGGG
AGGTCTGTATTGTGTACAGAAGGAAAGCATTGAGAGAACATATAATGTAGATGATGGGGCAATTCTCGTTGGCGTATATT
CACCTATAATACTTTTTGGAAAGATTACTGACAGCATATATAAGGATATGAAGACGGAGGTTGATACTTCGCCGGAGCAG
TTTACTAATAAGGAATATCTTGATGAATTATCAGGAGAGCTGTCATCTAAGATGTCCTGTCTTGTTGTAAGAAGGAATGG
AATTATTATATATAATTCAACAGAAGCACCAGACAGCGAAATTGTAAAGATTCTTCCTGATTATTCTGCTGATGAAGAGA
ATGTTTCTGATGTTGGAACTTACAAGGGGGGAGAGTACCAGAGTCTTATAAAACAGCTTAATTTTAAGGATTCAGAAGAT
AATTTTTACAGCGTGTCAATTGTTACTTCATTGAAACAGATTCTTCCACAGGTTAAGACATTTATAATGCAGGTTATATT
TGTTATAATTATGGTGTTAATTATTACAAGTCTTGGACTTACTCTGTGGATATACAGTTCTATTGTTAAGCCACTTAATA
AGCTGAAGCTTGCAACTGATAATATTAAAGAAGGCAATATGGATTTCGAGATGCCAAAGGTATCTAATAATGAAATCGGA
GATGTATGCCGGGATTTTGAGGAGATGAGAGTCGTACTTAAGCAGAGTGCGGAGGATAAGATTAAGTCTGATGCCGAGGA
AAAGGAGCTTATCAGAAATATTTCACATGACTTAAAGACACCGCTTACGGCTATTAAAGGATATGTGGAAGGCTTGCGTG
ACGGAATTGCCAACACGCCTGAAAAGCAGGCTAAGTATATCCAGACTATTGCTAACAAGGTTAATGATATGGACAAGCTG
ATTGATGAGCTTACTATATATTCAAGGCTTGATACTAACAGGGTTCCATATACATTTGTCAGATGTAATGTAAGTGACTA
TTTTGGAGACTGTTGTGAAGAGATAGGCACTGAGCTTGAGGCAAGCCAGATTGAACTGGAATATAATGACCATCTTACTG
AGCCGGCATATATGAATGTTGATCCGGAGCAGCTAAAGAGGGTTGTTAATAATATTATAAGTAACTCAGTTAAGTATATG
GCTGAGGGACGACAGGGAAAGATTAAGATTGACCTGTACGATGAAGGCGACTACATTCATGCAATATTCTCAGATAACGG
TATTGGCATTGCAGCTAAAGATGTTGAGAGAATATTTGAGCGTTTCTATAGAACTGATGAATCAAGAAACAGCAAGCATG
GTGGAAGTGGTATAGGCCTTGCAATTGTTAAGAAGATTGTTGAGGACCACAAAGGAAAAATATGGGCAGAGAGTGTAGAG
GGCGAAGGCACGACCATGCATCTTAATCTGCTTAAAGCAAAGGATGAAGAGAATCCTGAGAATGCATAA

Upstream 100 bases:

>100_bases
CCGTTACAGCTGTTTTAATTTATATTTAATAAAATTAATACATTTGTAATGTTACAAATATCCCTGTATATGGTAGTATT
GAGAGGAAAAGGGGTTAATT

Downstream 100 bases:

>100_bases
TGAAACTACACGAAAGGGGACTGGCTATGAGCAAGATATTAATTGTAGAAGATGAAGAGAGTATTGCAGATATTGAGAAG
GATTACCTTGAACTTAACGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MKLKNKLYISFCIMVILPVLLSGLALGGLYCVQKESIERTYNVDDGAILVGVYSPIILFGKITDSIYKDMKTEVDTSPEQ
FTNKEYLDELSGELSSKMSCLVVRRNGIIIYNSTEAPDSEIVKILPDYSADEENVSDVGTYKGGEYQSLIKQLNFKDSED
NFYSVSIVTSLKQILPQVKTFIMQVIFVIIMVLIITSLGLTLWIYSSIVKPLNKLKLATDNIKEGNMDFEMPKVSNNEIG
DVCRDFEEMRVVLKQSAEDKIKSDAEEKELIRNISHDLKTPLTAIKGYVEGLRDGIANTPEKQAKYIQTIANKVNDMDKL
IDELTIYSRLDTNRVPYTFVRCNVSDYFGDCCEEIGTELEASQIELEYNDHLTEPAYMNVDPEQLKRVVNNIISNSVKYM
AEGRQGKIKIDLYDEGDYIHAIFSDNGIGIAAKDVERIFERFYRTDESRNSKHGGSGIGLAIVKKIVEDHKGKIWAESVE
GEGTTMHLNLLKAKDEENPENA

Sequences:

>Translated_502_residues
MKLKNKLYISFCIMVILPVLLSGLALGGLYCVQKESIERTYNVDDGAILVGVYSPIILFGKITDSIYKDMKTEVDTSPEQ
FTNKEYLDELSGELSSKMSCLVVRRNGIIIYNSTEAPDSEIVKILPDYSADEENVSDVGTYKGGEYQSLIKQLNFKDSED
NFYSVSIVTSLKQILPQVKTFIMQVIFVIIMVLIITSLGLTLWIYSSIVKPLNKLKLATDNIKEGNMDFEMPKVSNNEIG
DVCRDFEEMRVVLKQSAEDKIKSDAEEKELIRNISHDLKTPLTAIKGYVEGLRDGIANTPEKQAKYIQTIANKVNDMDKL
IDELTIYSRLDTNRVPYTFVRCNVSDYFGDCCEEIGTELEASQIELEYNDHLTEPAYMNVDPEQLKRVVNNIISNSVKYM
AEGRQGKIKIDLYDEGDYIHAIFSDNGIGIAAKDVERIFERFYRTDESRNSKHGGSGIGLAIVKKIVEDHKGKIWAESVE
GEGTTMHLNLLKAKDEENPENA
>Mature_502_residues
MKLKNKLYISFCIMVILPVLLSGLALGGLYCVQKESIERTYNVDDGAILVGVYSPIILFGKITDSIYKDMKTEVDTSPEQ
FTNKEYLDELSGELSSKMSCLVVRRNGIIIYNSTEAPDSEIVKILPDYSADEENVSDVGTYKGGEYQSLIKQLNFKDSED
NFYSVSIVTSLKQILPQVKTFIMQVIFVIIMVLIITSLGLTLWIYSSIVKPLNKLKLATDNIKEGNMDFEMPKVSNNEIG
DVCRDFEEMRVVLKQSAEDKIKSDAEEKELIRNISHDLKTPLTAIKGYVEGLRDGIANTPEKQAKYIQTIANKVNDMDKL
IDELTIYSRLDTNRVPYTFVRCNVSDYFGDCCEEIGTELEASQIELEYNDHLTEPAYMNVDPEQLKRVVNNIISNSVKYM
AEGRQGKIKIDLYDEGDYIHAIFSDNGIGIAAKDVERIFERFYRTDESRNSKHGGSGIGLAIVKKIVEDHKGKIWAESVE
GEGTTMHLNLLKAKDEENPENA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=290, Percent_Identity=26.2068965517241, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1790346, Length=271, Percent_Identity=27.3062730627306, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI48994928, Length=233, Percent_Identity=28.755364806867, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=28.6995515695067, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790861, Length=324, Percent_Identity=24.6913580246914, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787894, Length=307, Percent_Identity=25.4071661237785, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789149, Length=451, Percent_Identity=23.2815964523282, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1786783, Length=310, Percent_Identity=24.5161290322581, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788549, Length=224, Percent_Identity=29.9107142857143, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1786912, Length=229, Percent_Identity=30.5676855895196, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788713, Length=229, Percent_Identity=24.8908296943231, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789808, Length=297, Percent_Identity=25.2525252525253, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=24.1935483870968, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=26.2222222222222, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789403, Length=335, Percent_Identity=25.0746268656716, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788279, Length=243, Percent_Identity=24.2798353909465, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56653; Mature: 56653

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKNKLYISFCIMVILPVLLSGLALGGLYCVQKESIERTYNVDDGAILVGVYSPIILFG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHH
KITDSIYKDMKTEVDTSPEQFTNKEYLDELSGELSSKMSCLVVRRNGIIIYNSTEAPDSE
HHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHCCCEEEEEEECCEEEECCCCCCHHH
IVKILPDYSADEENVSDVGTYKGGEYQSLIKQLNFKDSEDNFYSVSIVTSLKQILPQVKT
HHEECCCCCCCCCCHHHHCCCCCCHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHH
FIMQVIFVIIMVLIITSLGLTLWIYSSIVKPLNKLKLATDNIKEGNMDFEMPKVSNNEIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
DVCRDFEEMRVVLKQSAEDKIKSDAEEKELIRNISHDLKTPLTAIKGYVEGLRDGIANTP
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EKQAKYIQTIANKVNDMDKLIDELTIYSRLDTNRVPYTFVRCNVSDYFGDCCEEIGTELE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHCCCCC
ASQIELEYNDHLTEPAYMNVDPEQLKRVVNNIISNSVKYMAEGRQGKIKIDLYDEGDYIH
HHEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEE
AIFSDNGIGIAAKDVERIFERFYRTDESRNSKHGGSGIGLAIVKKIVEDHKGKIWAESVE
EEECCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCC
GEGTTMHLNLLKAKDEENPENA
CCCCEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MKLKNKLYISFCIMVILPVLLSGLALGGLYCVQKESIERTYNVDDGAILVGVYSPIILFG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHH
KITDSIYKDMKTEVDTSPEQFTNKEYLDELSGELSSKMSCLVVRRNGIIIYNSTEAPDSE
HHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHCCCEEEEEEECCEEEECCCCCCHHH
IVKILPDYSADEENVSDVGTYKGGEYQSLIKQLNFKDSEDNFYSVSIVTSLKQILPQVKT
HHEECCCCCCCCCCHHHHCCCCCCHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHH
FIMQVIFVIIMVLIITSLGLTLWIYSSIVKPLNKLKLATDNIKEGNMDFEMPKVSNNEIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
DVCRDFEEMRVVLKQSAEDKIKSDAEEKELIRNISHDLKTPLTAIKGYVEGLRDGIANTP
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EKQAKYIQTIANKVNDMDKLIDELTIYSRLDTNRVPYTFVRCNVSDYFGDCCEEIGTELE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHCCCCC
ASQIELEYNDHLTEPAYMNVDPEQLKRVVNNIISNSVKYMAEGRQGKIKIDLYDEGDYIH
HHEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEE
AIFSDNGIGIAAKDVERIFERFYRTDESRNSKHGGSGIGLAIVKKIVEDHKGKIWAESVE
EEECCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCC
GEGTTMHLNLLKAKDEENPENA
CCCCEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]