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The map label for this gene is murQ [H]

Identifier: 238897147

GI number: 238897147

Start: 5147684

End: 5148586

Strand: Direct

Name: murQ [H]

Synonym: KP1_5410

Alternate gene names: 238897147

Gene position: 5147684-5148586 (Clockwise)

Preceding gene: 238897146

Following gene: 238897148

Centisome position: 98.08

GC content: 62.02

Gene sequence:

>903_bases
ATGAGTATCGACCTGAGCAAACTGCTGACCGAGCGACGTAACGCCAACAGCGCCAACATTGACACCCTCTCCACCCTCGA
GATGCTGACGGTGATAAACCAGGAAGACCAGCAGGTAGCCCAGGCGATAACGCCCTATCTGCCGCAGATTGCCGAGGTGG
TGGATAAGGTCGCGGCAGCGCTGCAGGCCGGTGGCCGCTTGATTTACATTGGCGCGGGTACCTCAGGGCGTCTGGGGATC
CTCGATGCCAGCGAATGCCCACCGACCTTCGGCACCCGCCCGGAGCAGGTGGTGGGGATCATCGCCGGCGGACATAAAGC
GATTCTCAGCGCCGTGGAAAATGTGGAAGACAACAAAGCGCAGGGGGCGATGGATCTGCAGAACCTGAACTTCAGCAACC
GCGATGTGCTGGTGGGGCTGGCGGCCAGCGGACGCACGCCGTACGTCATTGGCGCCATGGAATACGCCCATAGTCAGAAT
GCCTTTGTCGCCATCGTCAGCTGTAACCCGCATGGCGAAATGGCCCAGCTGGCGGACGTGGCGATCACCCCGGTGGTCGG
CCCGGAAGTGGTCACTGGCTCTACCCGCCTGAAAGCCGGCACCGCGCAGAAGCTGGTGCTGAACATGATCTCCACCGGGG
CGATGATCCGCGTCGGCAAGGTGTACAGCAACCTGATGGTCGACGTCGAAGCGACCAACGCCAAGCTGATTGAGCGCCAG
GTCTCTATCGTGATGGAGGCTACCGACTGCGATCGCGCCACCGCCCAGAAGGCGCTGGAGGCCTGCGGCCGCCACTGTAA
AACGGCGATCGTGATGGTGCTGGCGGACTTAAGCGCCGCAGAGGCGCAGTCGCTGCTGGCGAAAAACAACGGCTATATCC
GCAAGGCGCTCAGCAACACCTGA

Upstream 100 bases:

>100_bases
CATTCTCGTATTATTCTCCACGTACTAATCGTGATACTCTTCACAGGCAAGGAATAAATAATTCCTTATACTGCGCGCCA
CTGAGAATAACGAGGTTTCT

Downstream 100 bases:

>100_bases
GCGCCGACAGACAGGTAACGGGCAATGGCAAAAATAACGAAAGAGATGATAGCGCGGATCCTCGCCCACGTGGGCGGCGC
CGCAAACGTCGCGCAGGCGG

Product: hypothetical protein

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSIDLSKLLTERRNANSANIDTLSTLEMLTVINQEDQQVAQAITPYLPQIAEVVDKVAAALQAGGRLIYIGAGTSGRLGI
LDASECPPTFGTRPEQVVGIIAGGHKAILSAVENVEDNKAQGAMDLQNLNFSNRDVLVGLAASGRTPYVIGAMEYAHSQN
AFVAIVSCNPHGEMAQLADVAITPVVGPEVVTGSTRLKAGTAQKLVLNMISTGAMIRVGKVYSNLMVDVEATNAKLIERQ
VSIVMEATDCDRATAQKALEACGRHCKTAIVMVLADLSAAEAQSLLAKNNGYIRKALSNT

Sequences:

>Translated_300_residues
MSIDLSKLLTERRNANSANIDTLSTLEMLTVINQEDQQVAQAITPYLPQIAEVVDKVAAALQAGGRLIYIGAGTSGRLGI
LDASECPPTFGTRPEQVVGIIAGGHKAILSAVENVEDNKAQGAMDLQNLNFSNRDVLVGLAASGRTPYVIGAMEYAHSQN
AFVAIVSCNPHGEMAQLADVAITPVVGPEVVTGSTRLKAGTAQKLVLNMISTGAMIRVGKVYSNLMVDVEATNAKLIERQ
VSIVMEATDCDRATAQKALEACGRHCKTAIVMVLADLSAAEAQSLLAKNNGYIRKALSNT
>Mature_299_residues
SIDLSKLLTERRNANSANIDTLSTLEMLTVINQEDQQVAQAITPYLPQIAEVVDKVAAALQAGGRLIYIGAGTSGRLGIL
DASECPPTFGTRPEQVVGIIAGGHKAILSAVENVEDNKAQGAMDLQNLNFSNRDVLVGLAASGRTPYVIGAMEYAHSQNA
FVAIVSCNPHGEMAQLADVAITPVVGPEVVTGSTRLKAGTAQKLVLNMISTGAMIRVGKVYSNLMVDVEATNAKLIERQV
SIVMEATDCDRATAQKALEACGRHCKTAIVMVLADLSAAEAQSLLAKNNGYIRKALSNT

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=295, Percent_Identity=57.6271186440678, Blast_Score=335, Evalue=3e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR000408
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31618; Mature: 31487

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50012 RCC1_3 ; PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDLSKLLTERRNANSANIDTLSTLEMLTVINQEDQQVAQAITPYLPQIAEVVDKVAAA
CCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LQAGGRLIYIGAGTSGRLGILDASECPPTFGTRPEQVVGIIAGGHKAILSAVENVEDNKA
HHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHEEEEEECCHHHHHHHHHCCCCCCC
QGAMDLQNLNFSNRDVLVGLAASGRTPYVIGAMEYAHSQNAFVAIVSCNPHGEMAQLADV
CCCCCHHCCCCCCCEEEEEEECCCCCCEEEEHHHHHCCCCCEEEEEEECCCCCHHHHHHH
AITPVVGPEVVTGSTRLKAGTAQKLVLNMISTGAMIRVGKVYSNLMVDVEATNAKLIERQ
HCCCCCCCCEECCCCEECCCHHHHHHHHHHHCCCCEEHHHHHHCEEEEEECCCHHHHHHH
VSIVMEATDCDRATAQKALEACGRHCKTAIVMVLADLSAAEAQSLLAKNNGYIRKALSNT
HHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHCCC
>Mature Secondary Structure 
SIDLSKLLTERRNANSANIDTLSTLEMLTVINQEDQQVAQAITPYLPQIAEVVDKVAAA
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LQAGGRLIYIGAGTSGRLGILDASECPPTFGTRPEQVVGIIAGGHKAILSAVENVEDNKA
HHCCCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHEEEEEECCHHHHHHHHHCCCCCCC
QGAMDLQNLNFSNRDVLVGLAASGRTPYVIGAMEYAHSQNAFVAIVSCNPHGEMAQLADV
CCCCCHHCCCCCCCEEEEEEECCCCCCEEEEHHHHHCCCCCEEEEEEECCCCCHHHHHHH
AITPVVGPEVVTGSTRLKAGTAQKLVLNMISTGAMIRVGKVYSNLMVDVEATNAKLIERQ
HCCCCCCCCEECCCCEECCCHHHHHHHHHHHCCCCEEHHHHHHCEEEEEECCCHHHHHHH
VSIVMEATDCDRATAQKALEACGRHCKTAIVMVLADLSAAEAQSLLAKNNGYIRKALSNT
HHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA