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The map label for this gene is avtA [H]

Identifier: 238897037

GI number: 238897037

Start: 5031360

End: 5032616

Strand: Direct

Name: avtA [H]

Synonym: KP1_5284

Alternate gene names: 238897037

Gene position: 5031360-5032616 (Clockwise)

Preceding gene: 238897036

Following gene: 238897042

Centisome position: 95.86

GC content: 55.77

Gene sequence:

>1257_bases
ATGACATTTTCCCTTTTCGGCGACAAATTCACCCGTCATTCAGGCATCACCCGCTTGATGGAAGACCTTAATGACGGTCT
GCGCACGCCGGGCGCTATTATGCTGGGCGGCGGCAACCCCGCTCAGATCCCGGAAATGAATGACTACTTCCAGCAGCTGC
TGGCCGACATGCTGGATAATGGCAAAGCCCTTGATGCGCTTTGTAATTATGATGGTCCACAGGGCAAAAGCGAGCTGCTG
GCTCTGCTGGCGAATATGCTGCGCGACGAGCTGGGCTGGGAGATCGAACCACAGAATATTGCGCTAACAAACGGCAGTCA
GAGCGCATTTTTCTACTTATTTAATCTGTTTGCAGGCCGTCGGGCAGATGGCACCACCCGTAAGGTACTGTTCCCACTGA
CGCCGGAATATATCGGCTACGCCGATGCCGGTCTGGAAGAGGATCTGTTCGTTGCCACCCGGCCGAACATCGAACTGCTG
CCGGAAGGCCAGTTTAAGTACCATGTTGATTTTGAGCATCTGCAGGTGACGGAAGAGACCGGGATGATCTGCGTCTCGCG
CCCCACCAACCCGACCGGCAACGTCATCACTGATGAAGAGCTGATCAAACTGGATGCGCTGGCGAATCAGCACGGGGTCC
CGCTGGTGATTGATAACGCCTACGGTGTACCGTTCCCGGGCATTATCTTTAGCGACGCCCGACCGCTGTGGAATCCGAAC
ATCGTGCTGTGTATGAGCCTGTCCAAGCTGGGCCTGCCGGGCAGCCGCTGCGGGATTATCATCGCCAACGAAAAAATCAT
CACCGCCATCAGCAACATGAACGGCATTATCAGCCTCGCCCCTGGCGGCATCGGGCCGGCAATGATGTGCGAAATGATTA
AACGACAGGATCTGCTGCGCCTGTCAGAGACGGTGATCAAGCCCTTCTATTACCAGCGGGTGCAGGAAACCATCGCCATT
ATTCGCCGCTATCTGCCGGAGGAGCGCTGCCTTATTCACAAACCGGAGGGGGCAATCTTCCTCTGGCTGTGGTTTAAGGA
TCTGCCGATCTCCACCGAGCTGCTGTATCAGCGGCTGAAAAAGCGCGGCGTGCTGATGGTGCCGGGGGATTACTTCTTCC
CTGGTCTGGATAAACCGTGGCCGCACACCCACCAGTGTATGCGCATGAACTATGTACCGGACCCGCAAAAAATCGAAGCC
GGAGTGAAAATCCTCGCCGAAGAGGTTGAATTTGCCTGGCGCGAACAGGAAGCATAA

Upstream 100 bases:

>100_bases
AGGATAAAGATAAAAACCTGCCTCCTCCCGCCGATTTGCACCACGCCAGCGCTGGCGTTATGGTTAGCCACTTTCCAGAA
CCACCGATAGACTATTCGCG

Downstream 100 bases:

>100_bases
TCTCTGACGCCGCGGGCGGGTAACGTTCGTCAGCGACCCCATTCACGCCAGCGCCAGCCGCTGGCGTTTTTGCGCGCATA
GCGCTTCCAGCTCCGCGGGA

Product: valine--pyruvate transaminase

Products: NA

Alternate protein names: Alanine--valine transaminase; Transaminase C [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MTFSLFGDKFTRHSGITRLMEDLNDGLRTPGAIMLGGGNPAQIPEMNDYFQQLLADMLDNGKALDALCNYDGPQGKSELL
ALLANMLRDELGWEIEPQNIALTNGSQSAFFYLFNLFAGRRADGTTRKVLFPLTPEYIGYADAGLEEDLFVATRPNIELL
PEGQFKYHVDFEHLQVTEETGMICVSRPTNPTGNVITDEELIKLDALANQHGVPLVIDNAYGVPFPGIIFSDARPLWNPN
IVLCMSLSKLGLPGSRCGIIIANEKIITAISNMNGIISLAPGGIGPAMMCEMIKRQDLLRLSETVIKPFYYQRVQETIAI
IRRYLPEERCLIHKPEGAIFLWLWFKDLPISTELLYQRLKKRGVLMVPGDYFFPGLDKPWPHTHQCMRMNYVPDPQKIEA
GVKILAEEVEFAWREQEA

Sequences:

>Translated_418_residues
MTFSLFGDKFTRHSGITRLMEDLNDGLRTPGAIMLGGGNPAQIPEMNDYFQQLLADMLDNGKALDALCNYDGPQGKSELL
ALLANMLRDELGWEIEPQNIALTNGSQSAFFYLFNLFAGRRADGTTRKVLFPLTPEYIGYADAGLEEDLFVATRPNIELL
PEGQFKYHVDFEHLQVTEETGMICVSRPTNPTGNVITDEELIKLDALANQHGVPLVIDNAYGVPFPGIIFSDARPLWNPN
IVLCMSLSKLGLPGSRCGIIIANEKIITAISNMNGIISLAPGGIGPAMMCEMIKRQDLLRLSETVIKPFYYQRVQETIAI
IRRYLPEERCLIHKPEGAIFLWLWFKDLPISTELLYQRLKKRGVLMVPGDYFFPGLDKPWPHTHQCMRMNYVPDPQKIEA
GVKILAEEVEFAWREQEA
>Mature_417_residues
TFSLFGDKFTRHSGITRLMEDLNDGLRTPGAIMLGGGNPAQIPEMNDYFQQLLADMLDNGKALDALCNYDGPQGKSELLA
LLANMLRDELGWEIEPQNIALTNGSQSAFFYLFNLFAGRRADGTTRKVLFPLTPEYIGYADAGLEEDLFVATRPNIELLP
EGQFKYHVDFEHLQVTEETGMICVSRPTNPTGNVITDEELIKLDALANQHGVPLVIDNAYGVPFPGIIFSDARPLWNPNI
VLCMSLSKLGLPGSRCGIIIANEKIITAISNMNGIISLAPGGIGPAMMCEMIKRQDLLRLSETVIKPFYYQRVQETIAII
RRYLPEERCLIHKPEGAIFLWLWFKDLPISTELLYQRLKKRGVLMVPGDYFFPGLDKPWPHTHQCMRMNYVPDPQKIEAG
VKILAEEVEFAWREQEA

Specific function: Unknown

COG id: COG3977

COG function: function code E; Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994949, Length=417, Percent_Identity=90.167865707434, Blast_Score=789, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.66 [H]

Molecular weight: Translated: 47011; Mature: 46880

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFSLFGDKFTRHSGITRLMEDLNDGLRTPGAIMLGGGNPAQIPEMNDYFQQLLADMLDN
CEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCC
GKALDALCNYDGPQGKSELLALLANMLRDELGWEIEPQNIALTNGSQSAFFYLFNLFAGR
CCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEECCCEEEEECCCCHHHHHHHHHHHCC
RADGTTRKVLFPLTPEYIGYADAGLEEDLFVATRPNIELLPEGQFKYHVDFEHLQVTEET
CCCCCCEEEEEECCHHHCCCCCCCCCCCEEEEECCCEEEEECCCEEEEEEHHHEEEECCC
GMICVSRPTNPTGNVITDEELIKLDALANQHGVPLVIDNAYGVPFPGIIFSDARPLWNPN
CEEEEECCCCCCCCEECHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEECCCCCCCCCC
IVLCMSLSKLGLPGSRCGIIIANEKIITAISNMNGIISLAPGGIGPAMMCEMIKRQDLLR
EEEEEEHHHCCCCCCCEEEEEECCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHH
LSETVIKPFYYQRVQETIAIIRRYLPEERCLIHKPEGAIFLWLWFKDLPISTELLYQRLK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEEECCCCCHHHHHHHHH
KRGVLMVPGDYFFPGLDKPWPHTHQCMRMNYVPDPQKIEAGVKILAEEVEFAWREQEA
HCCEEEECCCCCCCCCCCCCCCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TFSLFGDKFTRHSGITRLMEDLNDGLRTPGAIMLGGGNPAQIPEMNDYFQQLLADMLDN
EEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCC
GKALDALCNYDGPQGKSELLALLANMLRDELGWEIEPQNIALTNGSQSAFFYLFNLFAGR
CCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEECCCEEEEECCCCHHHHHHHHHHHCC
RADGTTRKVLFPLTPEYIGYADAGLEEDLFVATRPNIELLPEGQFKYHVDFEHLQVTEET
CCCCCCEEEEEECCHHHCCCCCCCCCCCEEEEECCCEEEEECCCEEEEEEHHHEEEECCC
GMICVSRPTNPTGNVITDEELIKLDALANQHGVPLVIDNAYGVPFPGIIFSDARPLWNPN
CEEEEECCCCCCCCEECHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEECCCCCCCCCC
IVLCMSLSKLGLPGSRCGIIIANEKIITAISNMNGIISLAPGGIGPAMMCEMIKRQDLLR
EEEEEEHHHCCCCCCCEEEEEECCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHH
LSETVIKPFYYQRVQETIAIIRRYLPEERCLIHKPEGAIFLWLWFKDLPISTELLYQRLK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEEECCCCCHHHHHHHHH
KRGVLMVPGDYFFPGLDKPWPHTHQCMRMNYVPDPQKIEAGVKILAEEVEFAWREQEA
HCCEEEECCCCCCCCCCCCCCCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2825136; 8041620; 9278503 [H]