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The map label for this gene is mdaB [H]

Identifier: 238896535

GI number: 238896535

Start: 4516310

End: 4516678

Strand: Direct

Name: mdaB [H]

Synonym: KP1_4722

Alternate gene names: 238896535

Gene position: 4516310-4516678 (Clockwise)

Preceding gene: 238896534

Following gene: 238896536

Centisome position: 86.05

GC content: 54.74

Gene sequence:

>369_bases
ATGAGCAACATCCTGATTATCAATGGGGCGAAAAAGTTCGCGCACTCTAATGGTCAACTGAACGACACCCTGACCGAGGT
CGCGGAGAGTTATCTGCGCGACGCCGGGCACGATGTTAAAAGCGTTCGCGCCGAAAGCGAGTACGACGTAAAAGAAGAAG
TACAGAATTTCCTGTGGGCCGATGTGGTGATCTGGCAGATGCCGGGCTGGTGGATGGGCGCTCCGTGGACGGTGAAAAAA
TATATGGATGACGTCTTTACCGAAGGCCACGGCTCGCTGTACGCCAGCGATGGCCGTACCCGCTCCGACGCCAGCAAAAA
ATATGGCTCCGGCGGCCTGGTGCAGGGGAAAAATATATGCTTTCTCTGA

Upstream 100 bases:

>100_bases
TATTGCTCATTTGGCAAAAGACTTTGCACATTTTGCTCATTTTACTGCCCCGCTTCGCGGGGTAAGATCGTCGGCAAATT
TTCATATATGAGGGTAAAAA

Downstream 100 bases:

>100_bases
CCTGGAACGCGCCGATGGAAGCCTTCACCGACAAAGACCAGTTCTTCCACGGCGTCGGCGTTGACGGCGTTTACCTGCCG
TTCCATAAAGCCAATCAGTT

Product: modulator of drug activity B

Products: NADP; a reduced quinone; reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MSNILIINGAKKFAHSNGQLNDTLTEVAESYLRDAGHDVKSVRAESEYDVKEEVQNFLWADVVIWQMPGWWMGAPWTVKK
YMDDVFTEGHGSLYASDGRTRSDASKKYGSGGLVQGKNICFL

Sequences:

>Translated_122_residues
MSNILIINGAKKFAHSNGQLNDTLTEVAESYLRDAGHDVKSVRAESEYDVKEEVQNFLWADVVIWQMPGWWMGAPWTVKK
YMDDVFTEGHGSLYASDGRTRSDASKKYGSGGLVQGKNICFL
>Mature_121_residues
SNILIINGAKKFAHSNGQLNDTLTEVAESYLRDAGHDVKSVRAESEYDVKEEVQNFLWADVVIWQMPGWWMGAPWTVKKY
MDDVFTEGHGSLYASDGRTRSDASKKYGSGGLVQGKNICFL

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae HI_0648 and S.pombe SPAC5H10.05c [H]

Homologues:

Organism=Escherichia coli, GI1789406, Length=117, Percent_Identity=88.8888888888889, Blast_Score=220, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: NA

Molecular weight: Translated: 13665; Mature: 13534

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNILIINGAKKFAHSNGQLNDTLTEVAESYLRDAGHDVKSVRAESEYDVKEEVQNFLWA
CCCEEEEECCHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHH
DVVIWQMPGWWMGAPWTVKKYMDDVFTEGHGSLYASDGRTRSDASKKYGSGGLVQGKNIC
HHHEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHCCCCCCCCCCCEE
FL
CC
>Mature Secondary Structure 
SNILIINGAKKFAHSNGQLNDTLTEVAESYLRDAGHDVKSVRAESEYDVKEEVQNFLWA
CCEEEEECCHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHH
DVVIWQMPGWWMGAPWTVKKYMDDVFTEGHGSLYASDGRTRSDASKKYGSGGLVQGKNIC
HHHEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHCCCCCCCCCCCEE
FL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; a quinone; Acceptor; NADPH [C]

Specific reaction: NADPH + a quinone = NADP + a reduced quinone Acceptor + NADPH = reduced acceptor + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]